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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Forkhead box K2

ILF, ILF1, FOXK2, interleukin enhancer binding factor 1
The protein encoded by this gene contains a fork head DNA binding domain. This protein can bind to the purine-rich motifs of the HIV long terminal repeat (LTR), and to the similar purine-rich motif in the interleukin 2 (IL2) promoter. It may be involved in the regulation of viral and cellular promoter elements. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, HAD, IgA, MNF, fibrillin-1
Papers on ILF
Forkhead box protein k1 recruits TET1 to act as a tumor suppressor and is associated with MRI detection.
New
Shen et al., Ningbo, China. In Jpn J Clin Oncol, Feb 2016
OBJECTIVE: Today, more and more evidence suggests that Foxk proteins (Foxk1 and Foxk2) work as transcriptional repressors in different kinds of cancer, but whether Foxk1 has a role in mediating tumorigenesis in breast cancer, the evidence is rare.
Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors.
New
Sharrocks et al., Manchester, United Kingdom. In Nucleic Acids Res, Dec 2015
Here, we have examined the binding properties of three Forkhead (FOX) transcription factors, FOXK2, FOXO3 and FOXJ3 in vivo.
Axial Diffusivity in the ILF and IFOF is Related to Autism Symptom Severity.
New
Behrmann et al., In J Vis, Oct 2015
Also, recent evidence suggests that the inferior longitudinal fasciculus (ILF), a fiber tract that connects posterior core regions with more anterior extended regions, is developmentally disrupted in autism (Koldewyn et al., 2014).
Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23.
New
Mabbott et al., Philadelphia, United States. In Mucosal Immunol, May 2015
Despite their similarities, ILF development in the SI and LI differs on a number of levels.
Up-regulation of NF45 correlates with Schwann cell proliferation after sciatic nerve crush.
New
Zhang et al., Nantong, China. In J Mol Neurosci, May 2015
Nuclear factor (NF)45 (also known as interleukin enhancer-binding factor (ILF)2), is a transcription factor that interacts with NF90 to regulate gene expression.
FOXKs promote Wnt/β-catenin signaling by translocating DVL into the nucleus.
New
Chen et al., Houston, United States. In Dev Cell, Apr 2015
Here we discovered two Forkhead box (FOX) transcription factors, FOXK1 and FOXK2, as bona fide DVL-interacting proteins.
Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer.
Lam et al., Rio de Janeiro, Brazil. In Oncogenesis, 2014
The forkhead transcription factor FOXK2 has recently been implicated in cancer cell proliferation and survival, but a role in cancer chemotherapeutic drug resistance has hitherto not been explored.
Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs.
Impact
Dynlacht et al., New York City, United States. In Nat Cell Biol, 2014
Here, we identify Foxk proteins (Foxk1 and Foxk2) as transcriptional repressors of autophagy in muscle cells and fibroblasts.
Visual search for feature conjunctions: an fMRI study comparing alcohol-related neurodevelopmental disorder (ARND) to ADHD.
Longstaffe et al., Winnipeg, Canada. In J Neurodev Disord, 2014
Analysis of DTI data using tract-based spatial statistics (TBSS) showed areas of significantly lower fractional anisotropy (FA) and higher mean diffusivity (MD) in the right inferior longitudinal fasciculus (ILF) in ARND compared to TD subjects.
FOXK2 transcription factor suppresses ERα-positive breast cancer cell growth through down-regulating the stability of ERα via mechanism involving BRCA1/BARD1.
Wu et al., Dalian, China. In Sci Rep, 2014
In this study, we showed that the forkhead transcription factor FOXK2 interacted with ERα, and inhibited ERα-regulated transcriptional activities by enhancing the ubiquitin-mediated degradation of ERα.
Sex differences in white matter integrity in youths with attention-deficit/hyperactivity disorder: a pilot study.
Lopez-Larson et al., Salt Lake City, United States. In Front Neurosci, 2014
In addition, both TBSS and separate ROI analyses revealed significant sex-by-diagnosis interactions for the corticospinal tract (CST), inferior longitudinal fasciculus (ILF) and SLF.
Differential induction of isolated lymphoid follicles in the gut by 18β-glycyrrhetinic acid.
Hardy et al., Bozeman, United States. In Plos One, 2013
We reported that GRA administered orally to mice induces B cell recruitment to isolated lymphoid follicles (ILF) in the small intestine and shortens the duration of rotavirus antigen shedding.
The forkhead transcription factor FOXK2 promotes AP-1-mediated transcriptional regulation.
GeneRIF
Sharrocks et al., Manchester, United Kingdom. In Mol Cell Biol, 2012
FOXK2 can promote transcriptional activation and is required for the efficient recruitment of AP-1 components to chromatin.
Cell cycle-dependent regulation of the forkhead transcription factor FOXK2 by CDK·cyclin complexes.
GeneRIF
Sharrocks et al., Manchester, United Kingdom. In J Biol Chem, 2010
Data show that FOXK2 is subject to control by cell cycle-regulated hyperphosphorylation occurring in CDK).cyclin-dependent manner with CDK1.cyclin B as the major kinase complex.
FOXK2 transcription factor is a novel G/T-mismatch DNA binding protein.
GeneRIF
Nakamura et al., Nagasaki, Japan. In J Biochem, 2010
FOXK2 is a G/T-mismatch DNA-binding protein and a deaminated DNA-binding protein
Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.
Impact
Fagarasan et al., Yokohama, Japan. In Immunity, 2008
These findings provide insight into the crosstalk between bacteria, ROR gamma t(+)LTi cells, SCs, DCs, and B cells required for ILF formation and establish a critical role of ILFs in T cell-independent IgA synthesis in gut.
Human FOX gene family (Review).
Review
Katoh et al., Japan. In Int J Oncol, 2004
Human Forkhead-box (FOX) gene family consists of at least 43 members, including FOXA1, FOXA2, FOXA3, FOXB1, FOXC1, FOXC2, FOXD1, FOXD2, FOXD3, FOXD4, FOXD5 (FOXD4L1), FOXD6 (FOXD4L3), FOXE1, FOXE2, FOXE3, FOXF1, FOXF2, FOXG1 (FOXG1B), FOXH1, FOXI1, FOXJ1, FOXJ2, FOXJ3, FOXK1, FOXK2, FOXL1, FOXL2, FOXM1, FOXN1, FOXN2 (HTLF), FOXN3 (CHES1), FOXN4, FOXN5 (FOXR1), FOXN6 (FOXR2), FOXO1 (FOXO1A), FOXO2 (FOXO6), FOXO3 (FOXO3A), FOXO4 (MLLT7), FOXP1, FOXP2, FOXP3, FOXP4, and FOXQ1.
Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora.
Impact
Honjo et al., Kyoto, Japan. In Science, 2002
Reduction of bacterial flora by antibiotic treatment of AID-/- mice abolished ILF hyperplasia as well as the germinal center enlargement seen in secondary lymphoid tissues.
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