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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 21 May 2016.

Interleukin 8

IL-8, Interleukin-8, NaF
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Interleukin-6, IL-10, CAN, HAD, V1a
Papers using IL-8 antibodies
Agents Classified by the IARC Monographs, Volumes 1–102.
Supplier
Fry Rebecca C. et al., In Environmental Health Perspectives, 2009
An OptEIA™ human IL-8 enzyme-linked immunosorbent assay (ELISA) (BD Biosciences, San Jose, CA) was ...
Cystic Fibrosis Airway Epithelial Ca2+i Signaling: the mechanism for the larger agonist-mediated Ca2+i signals in human cystic fibrosis airway epithelia.
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Zhou Wen-Liang, In PLoS ONE, 2004
... IL-6 and IL-8 ELISA kits were obtained from eBioscience (San Diego, CA), and ...
A Skin-selective Homing Mechanism for Human Immune Surveillance T Cells
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Moser Bernhard et al., In The Journal of Experimental Medicine, 2002
IL-6 (AS12), IL-8 (AS14), TNF-α (6401.1111),
Natural-killer like cells in the sheep: Functional characterization and regulation by pregnancy-associated proteins
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Hansen Peter J et al., In BMC Cell Biology, 2001
... was from Anaspec (San Jose, CA) and the ELISA MAX™ Set Deluxe kit for human IL-8 was obtained from BioLegend (San Diego, CA) ...
Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells
Supplier
Shimizu Tadamichi et al., In Mediators of Inflammation, 2001
... (CA); Paeoniflorin was from LKT Laboratories, Inc.; MIF, IL-6, and IL-8 ELISA kits were obtained from R&D Systems (Minneapolis); and the Western blot detection system was obtained from Cell Signaling Technology (Beverly, MA) ...
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Papers on IL-8
Gastric ghrelin, GOAT, leptin, and leptinR expression as well as peripheral serotonin are dysregulated in humans with obesity.
New
Bischoff et al., Stuttgart, Germany. In Neurogastroenterol Motil, Feb 2016
Interleukin 1 receptor a (IL1Ra), IL-8, IL-12, and monocyte chemoattractant protein 1 (IL1Ra) were increased and IL1Ra correlated negatively with serum leptin.
Inflammation in induced sputum after aluminium oxide exposure: an experimental chamber study.
New
Kongerud et al., Oslo, Norway. In Occup Environ Med, Feb 2016
CONCLUSIONS: The present study suggests that controlled exposure to Al2O3 particles at levels below PEL (TWA) induces airway inflammation in healthy humans marked by elevated neutrophils and elevated IL-8.
ANNALS EXPRESS: Cytokine profiles in overweight and obese subjects and normal weight individuals matched for age and gender.
New
Ghayour-Mobarhan et al., Mashhad, Iran. In Ann Clin Biochem, Feb 2016
The concentrations of serum interleukin-1α, -1β, -2, -4, -6, -8 and -10 (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, and IL-10), were measured in all subjects, together with serum vascular endothelial growth factor (VEGF), interferon γ (IFN-γ), epidermal growth factor (EGF), monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-α (TNF-α).
Could cytokine levels in the peri-implant crevicular fluid be used to distinguish between healthy implants and implants with peri-implantitis? A systematic review.
Review
New
Feres et al., Guarulhos, Brazil. In J Periodontal Res, Feb 2016
Proinflammatory cytokines [interleukin (IL)-1β, IL-6, IL-12, IL-17 and tumor necrosis factor-α) were the cytokines studied most commonly, followed by anti-inflammatory cytokines (IL-4 and IL-10), osteoclastogenesis-related cytokines (RANKL) and chemokines (IL-8).
Decidual Control of Trophoblast Invasion.
Review
New
Modi et al., Mumbai, India. In Am J Reprod Immunol, Feb 2016
The decidual secretions contain high amounts of pro-invasive factors that include IL-1β, IL-5, IL-6, IL-7, IL-8, IL-9, IL-13, IL-15, Eotaxin CCL11, IP-10 and RANTES, and anti-invasive factors IL-10, IL-12 and VEGF.
The Potential of Food-Protein Derived Anti-Inflammatory Peptides Against Various Chronic Inflammatory Diseases.
Review
New
Wu et al., Edmonton, Canada. In J Sci Food Agric, Jan 2016
Increasing scientific evidence has delineated that inflammatory markers such as TNF-α, IL-1, IL-6, IL-8, and CRP and different transcription factors such as NF-κB and STAT are the major key factors that regulate these inflammatory diseases.
Treatment of non-muscle invasive bladder cancer with Bacillus Calmette-Guerin (BCG): Biological markers and simulation studies.
Review
New
Startsev et al., Moscow, Russia. In Bba Clin, Dec 2015
We identified tumor associated macrophages (TAMs), human leukocyte antigen (HLA) class I, a combination of Ki-67/CK20, IL-2, IL-8 and IL-6/IL-10 ratio as the most promising markers for both pre-BCG and post-BCG treatment suitable for the simulation studies.
Effects of the New Generation Synthetic Reconstituted Surfactant CHF5633 on Pro- and Anti-Inflammatory Cytokine Expression in Native and LPS-Stimulated Adult CD14+ Monocytes.
New
Speer et al., Würzburg, Germany. In Plos One, Dec 2015
Subsequent expression of TNF-α, IL-1β, IL-8 and IL-10 mRNA was quantified by real-time quantitative PCR, corresponding intracellular cytokine synthesis was analyzed by flow cytometry.
Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.
New
Kim et al., Ch'ŏnan, South Korea. In Plos One, Dec 2015
Tβ4 activation with a Tβ4 peptide attenuated the H2O2-induced production of NO and PGE2 and up-regulated iNOS, COX-2, and osteoclastogenic cytokines (TNF-α, IL-1β, IL-6, IL-8, and IL-17) as well as reversed the effect on RANKL and OPG in PDLCs.
Acute Phase Proteins and Their Role in Periodontitis: A Review.
Review
New
Palagi et al., Guntūr, India. In J Clin Diagn Res, Nov 2015
The production of Acute phase proteins is regulated to a great extent by Cytokines such as IL-1, IL-6, IL-8, TNF-α and to a lesser extent by Glucocorticoid hormones.
Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants.
Impact
Hayday et al., London, United Kingdom. In Nat Med, 2014
Here we demonstrate that a major T cell effector function in human newborns is interleukin-8 (CXCL8) production, which has the potential to activate antimicrobial neutrophils and γδ T cells.
γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer.
Impact
Huang et al., Hangzhou, China. In Immunity, 2014
Activated inf-DCs induced γδT17 cells to secrete IL-8, tumor necrosis factor alpha, and GM-CSF with a concomitant accumulation of immunosuppressive PMN-MDSCs in the tumor.
α-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-κB signalling.
Impact
Ma et al., Houston, United States. In Nat Cell Biol, 2014
This stabilization in turn prevents nuclear localization of RelA and p50, leading to decreased expression of TNF-α, IL-8 and RelB.
Biological features of novel avian influenza A (H7N9) virus.
Impact
Shu et al., Beijing, China. In Nature, 2013
In acute serum samples of H7N9-infected patients, increased levels of the chemokines and cytokines IP-10, MIG, MIP-1β, MCP-1, IL-6, IL-8 and IFN-α were detected.
A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells.
Impact
Metcalfe et al., Bethesda, United States. In Immunity, 2013
In addition, gene targeting of t-FcεRIβ attenuated microtubule formation, degranulation, and IL-8 production downstream of Ca2+ signals.
Seminal plasma induces angiogenic chemokine expression in cervical cancer cells and regulates vascular function.
GeneRIF
Katz et al., Cape Town, South Africa. In Biochim Biophys Acta, 2012
Seminal plasma rapidly enhanced the expression of the angiogenic chemokines, interleukin (IL)-8 and growth regulated oncogene alpha (GRO) in HeLa cells.
Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells.
GeneRIF
Akiyama et al., Tokushima, Japan. In Oncol Rep, 2012
The enzymatic activity of thymidine phosphorylase was required for the enhanced expression of IL-8 in human cancer cells.
The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer.
GeneRIF
Majsterek et al., Łódź, Poland. In Dna Cell Biol, 2012
data showed that the IL-8 -251 T/A and IL-13 -1112 C/T polymorphisms might be associated with the inflammatory bowel disease and colorectal cancer occurrence
Role of mechanical stretching and lipopolysaccharide in early apoptosis and IL-8 of alveolar epithelial type II cells A549.
GeneRIF
Zhao et al., Haikou, China. In Asian Pac J Trop Med, 2012
Mechanical stretch can induce early apoptosis and IL-8 secretion. Mechanical stretch and lipopolysaccharide have an additive effect on early apoptosis and IL-8 production in human alveolar type 2 cells.
IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer.
GeneRIF
Gorczynski et al., Denizli, Turkey. In Clin Lab, 2011
In BevacizumAb therapy, serum IL8 levels were decreased in all patients, and thus, changes in such levels were not correlated with disease outcome.
More papers using IL-8 antibodies
Microarray analysis of eosinophils reveals a number of candidate survival and apoptosis genes
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Kankaanranta Hannu et al., In Journal of Inflammation (London, England), 2000
... (Miltenyi Biotec Ltd., Surrey, UK), human recombinant IL-5, GM-CSF and DuoSet ELISA Development System for IL-8 and MCP-1 (R&D system Europe, Abingdon, UK), May-Grünwald (Merck, Darmstadt, Germany), and Giemsa ...
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.
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Kyprianou Natasha, In PLoS ONE, 2000
... To examine the effect of IL-8 on radiation responses, LNCaP cells were pretreated with IL-8 (BD Biosciences) at concentrations of 0 to ...
Assay for redox-sensitive transcription factor.
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Hartl Dominik, In PLoS ONE, 1999
... Human IL-6 and IL-8 ELISA kits were from Diaclone (Stamford, CT) and R&D ...
Thrombin and leukocyte recruitment in endotoxemia.
Supplier
Woodman Richard C et al., In BMC Immunology, 1999
... fetal bovine serum (FBS) (Cansera International Inc., Toronto, ON), tumour necrosis factor (TNF) and interleukin-8 (IL-8) (Research Diagnostics Inc.,Flandere,NJ); HTMT dimaleate (6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)-heptanecarboxamide) ...
TNF-α and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway
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Pilette Charles et al., In Journal of Biomedicine and Biotechnology, 1999
... After washing, neutrophils were resuspended in RPMI-1640 and activated by 20 ng/ml IL-8 (R&D System, Minneapolis, MN) for 5 min followed by 1 nM formyl-Methionyl-Leucyl-Phenylalanine (fMLP) (Sigma Aldrich, Saint Louis, MO) for ...
Interleukin-1α producing synovial sarcoma with prolonged fever: a case report
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Sugitani Masahiko et al., In Acta Histochemica et Cytochemica, 1997
... Next, we immunohistochemically examined the localization of the proinflammatory cytokine, IL-8 (Abcam Ltd, Cambridge, UK), using ...
A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy
Supplier
Garry Robert F et al., In Virology Journal, 1987
... indicators (Abaxis, Inc.) and serum cytokine levels (Cambridge Biomedical [IL-1b, IL-10], BD Biosciences [IL-2, IL-4, IL-8, IL-12p70], R&D Systems [IL-5, IL-6], Thermo Scientific [TNF-α], BioVendor [TNF-β, IFN-γ]) ...
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