gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Mar 2014.

Interleukin 8

IL-8, Interleukin-8, NaF
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: Interleukin-6, CAN, IL-10, HAD, V1a
Papers using IL-8 antibodies
Agents Classified by the IARC Monographs, Volumes 1–102.
Supplier
Fry Rebecca C. et al., In Environmental Health Perspectives, 2009
An OptEIA™ human IL-8 enzyme-linked immunosorbent assay (ELISA) (BD Biosciences, San Jose, CA) was ...
Cystic Fibrosis Airway Epithelial Ca2+i Signaling: the mechanism for the larger agonist-mediated Ca2+i signals in human cystic fibrosis airway epithelia.
Supplier
Zhou Wen-Liang, In PLoS ONE, 2004
... IL-6 and IL-8 ELISA kits were obtained from eBioscience (San Diego, CA), and ...
A Skin-selective Homing Mechanism for Human Immune Surveillance T Cells
Supplier
Moser Bernhard et al., In The Journal of Experimental Medicine, 2002
IL-6 (AS12), IL-8 (AS14), TNF-α (6401.1111),
Natural-killer like cells in the sheep: Functional characterization and regulation by pregnancy-associated proteins
Supplier
Hansen Peter J et al., In BMC Cell Biology, 2001
... was from Anaspec (San Jose, CA) and the ELISA MAX™ Set Deluxe kit for human IL-8 was obtained from BioLegend (San Diego, CA) ...
Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells
Supplier
Shimizu Tadamichi et al., In Mediators of Inflammation, 2001
... (CA); Paeoniflorin was from LKT Laboratories, Inc.; MIF, IL-6, and IL-8 ELISA kits were obtained from R&D Systems (Minneapolis); and the Western blot detection system was obtained from Cell Signaling Technology (Beverly, MA) ...
more suppliers
Papers on IL-8
Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections.
New
Oliveira-Ferreira et al., Rio de Janeiro, Brazil. In Mem Inst Oswaldo Cruz, 04 Apr 2014
During the acute phase, P. vivax and P. falciparum patients had significantly higher interleukin (IL)-6, IL-8, IL-17, interferon-γ, tumour necrosis factor (TNF)-α, macrophage inflammatory protein-1β and granulocyte-colony stimulating factor levels than controls and maintained high levels during the convalescent phase.
A125: Immunomodulatory Factors Produced by Mesenchymal Stem Cells After in vitro Priming with Danger Signals.
New
Jones et al., Cleveland, United States. In Arthritis Rheumatol, 31 Mar 2014
LPS stimulated the production of mediators that affect mostly neutrophil chemotaxis and activation, including IL-8 (1.8 fold), CXCL7 (2 fold), CXCL5 (2.4 fold), CXCL1 (1.6 fold).
α-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-κB signalling.
New
Impact
Ma et al., Houston, United States. In Nat Cell Biol, 31 Mar 2014
This stabilization in turn prevents nuclear localization of RelA and p50, leading to decreased expression of TNF-α, IL-8 and RelB.
Efficacy and safety of long-term antibiotics (macrolides) for the treatment of chronic rhinosinusitis.
Review
New
Wallwork et al., Brisbane, Australia. In Curr Allergy Asthma Rep, 31 Mar 2014
Of the controlled trials, the one including CRS patients just without polyps, showed a significant effect in sino-nasal outcome test, saccharine transit time, nasal endoscopy, and IL-8 levels in lavage fluid after 12 weeks of roxithromycin, whereas, in the other RCT with a mixed study group of CRS patients with and without polyps, 12 weeks of azithromycin showed no effect compared to placebo.
A17: A Prospective Study Comparing Infectious Risks, Disease Activity, and Cytokine Alterations in Children with Juvenile Idiopathic Arthritis Treated with and without Tumor Necrosis Factor-alpha Inhibitors.
New
Toussi et al., New York City, United States. In Arthritis Rheumatol, 31 Mar 2014
TNF-α, interleukin (IL)-1β, IL-6, IL-8, IL-10, and IL-17 cytokine levels were collected at pre-specified time points.
Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: A systematic review of biomarker studies.
Review
New
Baune et al., Adelaide, Australia. In Neurosci Biobehav Rev, 07 Mar 2014
The non-specific association of chemokines including CXCL8 (IL-8), CCL2 (MCP-1), CCL3 (MIP-1α) and CCL5 (RANTES) with these disorders across diagnostic categories implies a generalized involvement of many chemokine systemic with psychiatric disease.
Helicobacter pylori gamma-glutamyl transpeptidase and its pathogenic role.
Review
New
Zarrilli et al., Pavia, Italy. In World J Gastroenterol, 21 Feb 2014
H. pylori GGT may also inhibit apoptosis and induce gastric epithelial cell proliferation through the induction of cyclooxygenase-2, epidermal growth factor-related peptides, inducible nitric oxide synthase and interleukin-8.
Investigation of the effects of curcumin on serum cytokines in obese individuals: a randomized controlled trial.
New
Ghayour-Mobarhan et al., Mashhad, Iran. In Scientificworldjournal, Dec 2013
Serum levels of IL-1 α , IL-1 β , IL-2, IL-4, IL-6, IL-8, IL-10, VEGF, IFN γ , EGF, MCP-1, and TNF α were measured using a multiplex Biochip Array Technology based method.
Modulation of keratin 1, 10 and involucrin expression as part of the complex response of the human keratinocyte cell line HaCaT to ultraviolet radiation.
New
Kubala et al., Czech Republic. In Interdiscip Toxicol, Dec 2013
This was accompanied by increased expression of c-Jun and MMP-1 and IL-6 and IL-8 production.
Biological features of novel avian influenza A (H7N9) virus.
New
Impact
Shu et al., Beijing, China. In Nature, Aug 2013
In acute serum samples of H7N9-infected patients, increased levels of the chemokines and cytokines IP-10, MIG, MIP-1β, MCP-1, IL-6, IL-8 and IFN-α were detected.
Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain.
Review
New
Haglund et al., Zürich, Switzerland. In Global Spine J, Jun 2013
However, past research clearly indicates that inflammatory mediators such as interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor-α are expressed at higher levels in "diseased" intervertebral disks.
A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells.
New
Impact
Metcalfe et al., Bethesda, United States. In Immunity, Jun 2013
In addition, gene targeting of t-FcεRIβ attenuated microtubule formation, degranulation, and IL-8 production downstream of Ca2+ signals.
Chemokine to the rescue: interleukin-8 mediates resistance to PI3K-pathway-targeted therapy in breast cancer.
Impact
Abraham, San Diego, United States. In Cancer Cell, 2013
In this issue of Cancer Cell, Britschgi and coworkers show that certain tumors acquire resistance to PI3K-mTOR inhibitors through activation of a JAK2-dependent pathway, leading to interleukin-8 secretion.
JAK2/STAT5 inhibition circumvents resistance to PI3K/mTOR blockade: a rationale for cotargeting these pathways in metastatic breast cancer.
Impact
Bentires-Alj et al., Basel, Switzerland. In Cancer Cell, 2013
Mechanistically, PI3K/mTOR inhibition increased IRS1-dependent activation of JAK2/STAT5 and secretion of IL-8 in several cell lines and primary breast tumors.
Seminal plasma induces angiogenic chemokine expression in cervical cancer cells and regulates vascular function.
GeneRIF
Katz et al., Cape Town, South Africa. In Biochim Biophys Acta, 2012
Seminal plasma rapidly enhanced the expression of the angiogenic chemokines, interleukin (IL)-8 and growth regulated oncogene alpha (GRO) in HeLa cells.
Effective Strategies for the Management of Pyoderma Gangrenosum.
Review
Maverakis et al., Sacramento, United States. In Adv Wound Care (new Rochelle), 2012
Although the pathogenesis is still not well understood, it is clear that PG is associated with the upregulation of several cytokines including interleukin 8 (IL-8), tumor necrosis factor (TNF), IL-1β, IL-6, and interferon gamma, among many others.
Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells.
GeneRIF
Akiyama et al., Tokushima, Japan. In Oncol Rep, 2012
The enzymatic activity of thymidine phosphorylase was required for the enhanced expression of IL-8 in human cancer cells.
The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer.
GeneRIF
Majsterek et al., Łódź, Poland. In Dna Cell Biol, 2012
data showed that the IL-8 -251 T/A and IL-13 -1112 C/T polymorphisms might be associated with the inflammatory bowel disease and colorectal cancer occurrence
Role of mechanical stretching and lipopolysaccharide in early apoptosis and IL-8 of alveolar epithelial type II cells A549.
GeneRIF
Zhao et al., Haikou, China. In Asian Pac J Trop Med, 2012
Mechanical stretch can induce early apoptosis and IL-8 secretion. Mechanical stretch and lipopolysaccharide have an additive effect on early apoptosis and IL-8 production in human alveolar type 2 cells.
IL8 and serum soluble TRAIL levels following anti-VEGF monoclonal antibody treatment in patients with metastatic colon cancer.
GeneRIF
Gorczynski et al., Denizli, Turkey. In Clin Lab, 2011
In BevacizumAb therapy, serum IL8 levels were decreased in all patients, and thus, changes in such levels were not correlated with disease outcome.
More papers using IL-8 antibodies
Microarray analysis of eosinophils reveals a number of candidate survival and apoptosis genes
Supplier
Kankaanranta Hannu et al., In Journal of Inflammation (London, England), 2000
... (Miltenyi Biotec Ltd., Surrey, UK), human recombinant IL-5, GM-CSF and DuoSet ELISA Development System for IL-8 and MCP-1 (R&D system Europe, Abingdon, UK), May-Grünwald (Merck, Darmstadt, Germany), and Giemsa ...
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.
Supplier
Kyprianou Natasha, In PLoS ONE, 2000
... To examine the effect of IL-8 on radiation responses, LNCaP cells were pretreated with IL-8 (BD Biosciences) at concentrations of 0 to ...
Assay for redox-sensitive transcription factor.
Supplier
Hartl Dominik, In PLoS ONE, 1999
... Human IL-6 and IL-8 ELISA kits were from Diaclone (Stamford, CT) and R&D ...
Thrombin and leukocyte recruitment in endotoxemia.
Supplier
Woodman Richard C et al., In BMC Immunology, 1999
... fetal bovine serum (FBS) (Cansera International Inc., Toronto, ON), tumour necrosis factor (TNF) and interleukin-8 (IL-8) (Research Diagnostics Inc.,Flandere,NJ); HTMT dimaleate (6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)-heptanecarboxamide) ...
TNF-α and serum induce SKALP/elafin gene expression in human keratinocytes by a p38 MAP kinase-dependent pathway
Supplier
Pilette Charles et al., In Journal of Biomedicine and Biotechnology, 1999
... After washing, neutrophils were resuspended in RPMI-1640 and activated by 20 ng/ml IL-8 (R&D System, Minneapolis, MN) for 5 min followed by 1 nM formyl-Methionyl-Leucyl-Phenylalanine (fMLP) (Sigma Aldrich, Saint Louis, MO) for ...
Interleukin-1α producing synovial sarcoma with prolonged fever: a case report
Supplier
Sugitani Masahiko et al., In Acta Histochemica et Cytochemica, 1997
... Next, we immunohistochemically examined the localization of the proinflammatory cytokine, IL-8 (Abcam Ltd, Cambridge, UK), using ...
A prospective study of maternal and fetal outcome in acute Lassa fever infection during pregnancy
Supplier
Garry Robert F et al., In Virology Journal, 1987
... indicators (Abaxis, Inc.) and serum cytokine levels (Cambridge Biomedical [IL-1b, IL-10], BD Biosciences [IL-2, IL-4, IL-8, IL-12p70], R&D Systems [IL-5, IL-6], Thermo Scientific [TNF-α], BioVendor [TNF-β, IFN-γ]) ...
share on facebooktweetadd +1mail to friends