CD8αα TCRαβ Intraepithelial Lymphocytes in the Mouse Gut.
Chongqing, China. In Dig Dis Sci, Feb 2016
For instance, epithelial cells and nearby immune cells secrete a number of cytokines, including interleukin-15 (IL-15), IL-7, and transforming growth factor-β, resulting in an assortment of cellular responses, including activation of master transcription factors, cell proliferation, and cytokine secretion.
Decidual Control of Trophoblast Invasion.
Mumbai, India. In Am J Reprod Immunol, Feb 2016
The decidual secretions contain high amounts of pro-invasive factors that include IL-1β, IL-5, IL-6, IL-7, IL-8, IL-9, IL-13, IL-15, Eotaxin CCL11, IP-10 and RANTES, and anti-invasive factors IL-10, IL-12 and VEGF.
Common gamma chain cytokines in combinatorial immune strategies against cancer.
Nashville, United States. In Immunol Lett, Jan 2016
Common γ chain (γC) cytokines, namely IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21 are important for the proliferation, differentiation, and survival of lymphocytes that display antitumor activity, thus stimulating considerable interest for the use of cytokines in cancer immunotherapy.
IL-7 signalling represses Bcl-6 and the TFH gene program.
Roanoke, United States. In Nat Commun, Dec 2015
Exposure of this potentially bi-potent cell population to IL-6 favours the TFH gene program, whereas IL-7 signalling represses TFH-associated genes including Bcl6 and Cxcr5, but not the TCM-related genes Klf2 and Sell.
Inflammatory profiles in canine intervertebral disc degeneration.
Utrecht, Netherlands. In Bmc Vet Res, Dec 2015
Cytokines interleukin (IL)-2, IL-6, IL-7, IL-8, IL-10, IL-15, IL-18, immune protein (IP)-10, tumor necrosis factor (TNF)-α, and granulocyte macrophage colony-stimulating factor (GM-CSF) were not detectable in the samples.
Histone reader BRWD1 targets and restricts recombination to the Igk locus.
Chicago, United States. In Nat Immunol, Oct 2015
Here we show that developmental downregulation of interleukin 7 (IL-7)-receptor signaling in small pre-B cells induced expression of the bromodomain-family member BRWD1, which was recruited to a specific epigenetic landscape at Igk dictated by pre-B cell receptor (pre-BCR)-dependent Erk activation.