Allergen-encoded signals that control allergic responses.
Houston, United States. In Curr Opin Allergy Clin Immunol, Feb 2016
RECENT FINDINGS: The last few years have seen crucial advances in how innate immune cells such as innate lymphoid cells group 2 and airway epithelial cells and related molecular pathways through organismal proteinases and innate immune cytokines, such as thymic stromal lymphopoietin, IL-25, and IL-33 contribute to allergy and asthma.
Interleukin (IL)-25: Pleiotropic roles in asthma.
Beijing, China. In Respirology, Jan 2016
UNASSIGNED: IL-25, also named IL-17E, is a distinct member of the IL-17 cytokine family, which can promote and augment T helper type 2 (Th2) responses locally or systemically.
Drivers of chronic rhinosinusitis: Inflammation versus infection.
Boston, United States. In J Allergy Clin Immunol, Dec 2015
Conversely, certain innate factors, namely IL-25, IL-33, and thymic stromal lymphopoietin (TSLP), are elaborated by sinus epithelial cells in response to microbial stimulation or airway injury and promote local TH2 inflammation.
Barrier Epithelial Cells and the Control of Type 2 Immunity.
Gent, Belgium. In Immunity, Aug 2015
These ECs mount a prototypical response made up of chemokines, innate cytokines such as interleukin-1 (IL-1), IL-25, IL-33, and thymic stromal lymphopoietin (TSLP), as well as the alarmins uric acid, ATP, HMGB1, and S100 proteins.