ILC2s and fungal allergy.
Rochester, United States. In Allergol Int, 31 Jul 2015
In mouse models of fungus-induced allergic airway inflammation, IL-33, IL-25, and TSLP are released by airway epithelial cells.
Role of IL-25 in Immunity.
Īlām, Iran. In J Clin Diagn Res, Apr 2015
IL-25 a 2o KDa protein mostly known as IL-17E, encoded by chromosome 14, and containing 117 amino acids.
Epithelial cytokines and pulmonary allergic inflammation.
London, United Kingdom. In Curr Opin Immunol, Mar 2015
UNASSIGNED: The triad of epithelial derived cytokines, IL-25, IL-33 and TSLP are important for the initiation and development of pulmonary immune responses to environmental stimuli.
Group 2 Innate Lymphoid Cells in Health and Disease.
New York City, United States. In Cold Spring Harb Perspect Biol, Feb 2015
The epithelial cell-derived cytokines IL-25, IL-33, and TSLP regulate the activation and effector functions of ILC2s, and recent studies suggest that their responsiveness to these cytokines and other factors may depend on their tissue environment.
Clarithromycin and dexamethasone show similar anti-inflammatory effects on distinct phenotypic chronic rhinosinusitis: an explant model study.
Wuhan, China. In Bmc Immunol, Dec 2014
RESULTS: We found that both clarithromycin and dexamethasone up-regulated the production of anti-inflammatory mediators (Clara cell 10-kDa protein and interleukin (IL)-10), whereas down-regulated the production of Th2 response and eosinophilia promoting molecules (thymic stromal lymphopoietin, IL-25, IL-33, CD80, CD86, OX40 ligand, programmed cell death ligand 1, CCL17, CCL22, CCL11, CCL5, IL-5, IL-13, and eosinophilic cationic protein) and Th1 response and neutrophilia promoting molecules (CXCL8, CXCL5, CXCL10, CXCL9, interferon-γ, and IL-12), from sinonasal mucosa from distinct phenotypic CRS.
TH2, allergy and group 2 innate lymphoid cells.
New Haven, United States. In Nat Immunol, 2013
The initiation of type 2 immune responses by the epithelial cell-derived cytokines IL-25, IL-33 and TSLP has been an area of extensive research in the past decade.