44-plex cytokine profile of cholesteatoma.
In Acta Otolaryngol, 21 Dec 2013
The novel discovery of high levels of interleukin 21 (IL21) in cholesteatoma could explain the expansive growth and could serve as future drug target, as for example also suggested for psoriasis.
Repairing thymic function.
Lisbon, Portugal. In Curr Opin Organ Transplant, Jun 2013
RESULTS: Recent studies have assigned a role for IL-22 in the regeneration of thymic epithelium, and for microRNAs in the modulation of its survival and function.
Cytokines and T cells in atopic dermatitis.
Chieti, Italy. In Eur Cytokine Netw, Mar 2013
Several effector T cell subsets, such as pro-inflammatory cells like Th9, Th17 and Th22 cells, expressing high levels of IL-9, IL-17 and IL-22, together with the anti-inflammatory, immuno-modulating Treg cells constitutively producing IL-10, seem to play a role in this condition.
IL-22, not simply a Th17 cytokine.
San Francisco, United States. In Immunol Rev, Mar 2013
Interleukin-22 (IL-22) has important functions in host defense at mucosal surfaces as well as in tissue repair.
Th17 cell development: from the cradle to the grave.
Palo Alto, United States. In Immunol Rev, Mar 2013
Interleukin-23 (IL-23) is one of the key cytokines that shapes the development and function of Th17 cells with characteristic expression of retinoic acid receptor-related orphan receptor γ-t (RORγt), IL-17, IL-22, and granulocyte macrophage colony-stimulating factor (GM-CSF).