Cerebellar ataxia induced by 3-AP affects immunological function.
Nantong, China. In Neuro Endocrinol Lett, 27 Sep 2015
Expression of the T helper (Th)1- and Th17-related cytokines, IFN-γ, IL-2, IL-17 and IL-22, was downregulated in CD4+ cells in cerebellar ataxia rats, while expression of the Th2 and regulatory T (Treg)-related cytokines, IL-4, IL-5, IL-10 and transforming growth factor (TGF)-β, was upregulated.
High throughput screening of cytokines, chemokines and matrix metalloproteinases in wound fluid induced by mammary surgery.
Dalian, China. In Oncotarget, 10 Sep 2015
The WF harvested from patients underwent NAC showed significant higher profiles of interleukin-1β (IL-1β), IL-4, IL-6, IL-17F, IL-21, IL-23, IL-25, IL-31, Interferon γ (IFNγ), CD40 ligand (CD40L), tumor necrosis factor α (TNFα), CXCL1, CXCL2, CXCL5, CCL3, CCL7 and CCL20.
Th22 cells in autoimmunity: a review of current knowledge.
Karaj, Iran. In Eur Ann Allergy Clin Immunol, 31 Jul 2015
This T helper subset, by producing pro-inflammatory cytokines such as IL-22 and tumor necrosis factor-α (TNF-α), is implicated in the pathogenesis of inflammatory and autoimmune disorder.
Curcumin inhibits proliferation of interleukin-22-treated HaCaT cells.
Lanzhou, China. In Int J Clin Exp Med, Dec 2014
UNASSIGNED: The interleukin (IL)-23/IL-17A/IL-22 cytokine axis plays a critical role in the pathogenesis of psoriasis, wherein IL-22 effects on epidermal alternations by inhibiting differentiation and inducing keratinocyte proliferation.
Fibrosis Related Inflammatory Mediators: Role of the IL-10 Cytokine Family.
Budapest, Hungary. In Mediators Inflamm, Dec 2014
In the present review we provide an overview of the common key mediators of organ fibrosis highlighting the role of interleukin-10 (IL-10) cytokine family members (IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26), which recently came into focus as tissue remodeling-related inflammatory cytokines.
Th22 cells in allergic disease.
München, Germany. In Allergo J Int, Dec 2014
Th22 cells are terminally differentiated and very specialized T helper cells characterized by the secretion of their signature cytokine IL-22 and lack of IL-4, IL-17 and IFN-γ.
Interleukin-22: immunobiology and pathology.
In Annu Rev Immunol, Dec 2014
Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T helper (Th) 17 cells, γδ T cells, NKT cells, and newly described innate lymphoid cells (ILCs).