Interleukin-22: Biomarker of maternal and fetal inflammation?
Roma, Italy. In Immunol Res, 19 Dec 2014
IL-22 was detected in nearly all maternal samples [median value 693.115 pg/ml (599.91-809.91 pg/ml)], with no statistical difference between the groups, but with a tendency to increased levels among preeclamptic women.
Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness.
Chicago, United States. In Nature, 30 Nov 2014
Here we show that systemic exposure to Toll-like receptor (TLR) ligands causes rapid α(1,2)-fucosylation of small intestine epithelial cells (IECs) in mice, which requires the sensing of TLR agonists, as well as the production of interleukin (IL)-23 by dendritic cells, activation of innate lymphoid cells and expression of fucosyltransferase 2 (Fut2) by IL-22-stimulated IECs.
Interleukin-17 in human inflammatory diseases.
Tehrān, Iran. In Postepy Dermatol Alergol, Aug 2014
Human Th17 pro-inflammatory cells are currently defined as cells that produce IL-17A and F, tumor necrosis factor (TNF)-α, IL-6, IL-21, IL-22 and IL-23.
Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer.
Saint Louis, United States. In Scientifica (cairo), Dec 2013
Here, we review the roles of major cytokines that regulate human NK cell development, survival, and function, including IL-2, IL-12, IL-15, IL-18, and IL-21, and their translation to the clinic as immunotherapy agents.
Role of IL-22 in microbial host defense.
San Francisco, United States. In Curr Top Microbiol Immunol, Dec 2013
IL-22 is the best-studied member of the IL-20 subfamily, and exemplifies the diverse biological effects of this subfamily.