miRNA-Regulated Key Components of Cytokine Signaling Pathways and Inflammation in Rheumatoid Arthritis.
Ch'unch'ŏn, South Korea. In Med Res Rev, Feb 2016
Moreover, we have tried to portray the role of various miRNAs in different cytokines such as TNF-α, IL-1, IL-6, IL-10, IL-17, IL-18, IL-21, and granulocyte macrophage colony-stimulating factor (GMCSF).
Interleukin-1 and inflammasomes in ALD/AAH and NAFLD/NASH.
Innsbruck, Austria. In Hepatology, Feb 2016
This sensitization enhances the production of various pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-α (TNFα), thereby contributing to hepatocyte dysfunction, necrosis, and apoptosis and the generation of extracellular matrix proteins leading to fibrosis/cirrhosis.
Microarray and whole-exome sequencing analysis of familial Behçet's disease patients.
Suita, Japan. In Sci Rep, Dec 2015
They include heterozygous SNVs in the genes encoding IL-1 receptor-associated kinase 4 (IRAK4), nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain-containing 14 (NRP14) and melanoma antigen-encoding gene E2 (MAGEE2); IRAK4 harbors a missense mutation, whereas NRP14 and MAGEE2 harbor nonsense mutations.