Getting nervous about immunity.
Urbana, United States. In Semin Immunol, 17 Mar 2014
Neuroscientists now know that the first formally defined cytokine, IL-1, activates a discrete population of hypothalamic neurons.
Molecular determinants of sterile inflammation.
Tokyo, Japan. In Curr Opin Immunol, 28 Feb 2014
Tissue resident macrophages recognize the danger signals released from necrotic cells via the pattern recognition receptors and secrete IL-1 that results in acute neutrophilic inflammation.