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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Interleukin 13 receptor, alpha 2

IL-13Ralpha2, IL-13 receptor, IL-13 receptor alpha2
The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on IL-13Ralpha2
High expression of IL-13 receptor α2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.
Casal et al., Madrid, Spain. In Cancer Res, 2012
high expression of IL-13Ralpha2 was associated with later stages of disease progression and poor outcome in patients with colorectal cancer
Equilibrium and kinetic analysis of human interleukin-13 and IL-13 receptor alpha-2 complex formation.
Lacy, Radnor, United States. In J Mol Recognit, 2012
IL-13Ralpha2 is a high affinity receptor for IL-13 binding: implications in the understanding of the role of IL-13-R110Q in the disease state.
Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression.
Radstake et al., Nijmegen, Netherlands. In J Rheumatol, 2012
Data showed that polymorphisms in IL4, IL13, and their receptors do not play a role in SSc and do not influence the expression of their corresponding transcript in peripheral blood cells.
A novel combination immunotherapy for cancer by IL-13Rα2-targeted DNA vaccine and immunotoxin in murine tumor models.
Puri et al., Bethesda, United States. In J Immunol, 2011
When combined with IL-13Ralpha2 DNA cancer vaccine, Pseudomonas aeruginosa exotoxin A mediates synergistic antitumor effects on tumor growth and metastasis in established murine breast carcinoma and sarcoma tumor models.
Association of polymorphisms in genes encoding IL-4, IL-13 and their receptors with atopic dermatitis in a Korean population.
Yang et al., Cleveland, United States. In Exp Dermatol, 2011
did not identify any SNPs in the IL-4, IL-4R and IL-13Ralpha2 genes that were associated with atopic dermatitis
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