Discrimination between active and latent tuberculosis based on the ratio of antigen-specific to mitogen-induced IP-10 production.
Seoul, South Korea. In J Clin Microbiol, 26 Dec 2014
Whole blood samples from 33 active TB patients and 20 individuals with LTBI, and 26 non-TB controls were applied to the commercial IFN-γ release assay QuantiFERON-TB Gold In Tube, and the plasma was analyzed for IL-2, IL-6, IL-8, IL-10, IL-13, TNF-α, IFN-γ, MIG, IP-10, I-TAG, and MCP-1 by using a commercial cytometric bead array.
GATA-3 function in innate and adaptive immunity.
Rotterdam, Netherlands. In Immunity, Sep 2014
The zinc-finger transcription factor GATA-3 has received much attention as a master regulator of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4), IL-5, and IL-13 expression.
Asthma: pathogenesis and novel drugs for treatment.
Denver, United States. In Bmj, Dec 2013
Several new classes of asthma drugs-including ultra long acting β agonists and modulators of the interleukin 4 (IL-4), IL-5, IL-13, and IL-17 pathways-have been evaluated in randomized controlled trials.