GATA-3 function in innate and adaptive immunity.
Rotterdam, Netherlands. In Immunity, Sep 2014
The zinc-finger transcription factor GATA-3 has received much attention as a master regulator of T helper 2 (Th2) cell differentiation, during which it controls interleukin-4 (IL-4), IL-5, and IL-13 expression.
Asthma: pathogenesis and novel drugs for treatment.
Denver, United States. In Bmj, Dec 2013
Several new classes of asthma drugs-including ultra long acting β agonists and modulators of the interleukin 4 (IL-4), IL-5, IL-13, and IL-17 pathways-have been evaluated in randomized controlled trials.