Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide.
In PLoS ONE, 2008
... or PE-Cy5-conjugated anti-CD3, CD4, CD8, CD25, F4/80, CD206, IgG2b and IgG2a mAb, IFNγ, IL-12p70, IL-4, IL-10 and TGF-β1 ELISA kits were purchased from eBioscience (San Diego, CA) ... 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy.more suppliers
In PLoS ONE, 2004
... The mAbs against mouse CD3, CD28, IL-4, IL-5, IL-13, TNFα, IL-6, IL-8, IFN-γ and IL-10 ELISA kits were purchased from Biolegend (California, USA) ...
Changes of synapses in experimental autoimmune encephalomyelitis by using Fasudil.
Datong, China. In Wound Repair Regen, 20 Feb 2016
Neurotrophic factor BDNF and GDNF as well as immunomodulatory cytokine IL-10 in spinal cord were elevated in Fasudil-treated mice, while inflammatory cytokine IL-17, IL-1β, IL-6 and TNF-⟨ were obviously inhibited, accompanied by the decrease of inflammatory M1 iNOS and the increase of anti-inflammatory M2 Arg-1, providing a microenvironment that contributes to synaptic protection.
miRNA-Regulated Key Components of Cytokine Signaling Pathways and Inflammation in Rheumatoid Arthritis.
Ch'unch'ŏn, South Korea. In Med Res Rev, 20 Feb 2016
Moreover, we have tried to portray the role of various miRNAs in different cytokines such as TNF-α, IL-1, IL-6, IL-10, IL-17, IL-18, IL-21, and granulocyte macrophage colony-stimulating factor (GMCSF).
Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity.
Beersheba, Israel. In Int J Obes (lond), 20 Feb 2016
Bafilomycin-A1 pre-treatment of AT explants from high fat fed (HFF) mice had no effect on the secretion of some adipose tissue-derived endocrine factors, but partially or fully reversed obesity-related changes in secretion of a sub-set of adipo-cytokines by >35%, including the obesity-associate up-regulation of IL-6, VEGF, TNFα and certain IGFBP's, and down-regulated secretion of IL-10 and adiponectin.
Effect of yeast-derived products and distillers dried grains with solubles (DDGS) on antibody-mediated immune response and gene expression of pattern recognition receptors and cytokines in broiler chickens immunized with T-cell dependent antigens.
Winnipeg, Canada. In Poult Sci, 19 Feb 2016
On d 35, 5 birds per treatment were euthanized and the tissue samples from the cecal tonsils were collected to assess the gene expression of toll-like receptors TLR2b, TLR4, and TLR21, monocyte mannose receptor (MMR), and cytokines IL-10, IL-13, IL-4, IL-12p35, and IFN-γ.
ANNALS EXPRESS: Cytokine profiles in overweight and obese subjects and normal weight individuals matched for age and gender.
Mashhad, Iran. In Ann Clin Biochem, 18 Feb 2016
The concentrations of serum interleukin-1α, -1β, -2, -4, -6, -8 and -10 (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, and IL-10), were measured in all subjects, together with serum vascular endothelial growth factor (VEGF), interferon γ (IFN-γ), epidermal growth factor (EGF), monocyte chemoattractant protein-1 (MCP-1) and tumor necrosis factor-α (TNF-α).
Establishment of Elevated Serum Levels of IL-10, IL-8 and TNF-β as Potential Peripheral Blood Biomarkers in Tubercular Lymphadenitis: A Prospective Observational Cohort Study.
Delhi, India. In Plos One, 31 Dec 2015
To assess this twelve cytokines (Tumor Necrosis Factor (TNF)-α, Interferon (IFN) -γ, Interleukin (IL)-2, IL-12, IL-18, IL-1β, IL-10, IL-6, IL-4, IL-1Receptor antagonist (IL-1Ra), IL-8 and TNF-β, which have a role in pathogenesis of tuberculosis, were tested as potential peripheral blood biomarkers to aid the diagnosis of TL when routine investigations prove to be of limited value.
Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses.
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Buenos Aires, Argentina. In Cell, Oct 2015
Melatonin induces the expression of the repressor transcription factor Nfil3, blocking the differentiation of pathogenic Th17 cells and boosts the generation of protective Tr1 cells via Erk1/2 and the transactivation of the IL-10 promoter by ROR-α.