Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide.
In PLoS ONE, 2008
... or PE-Cy5-conjugated anti-CD3, CD4, CD8, CD25, F4/80, CD206, IgG2b and IgG2a mAb, IFNγ, IL-12p70, IL-4, IL-10 and TGF-β1 ELISA kits were purchased from eBioscience (San Diego, CA) ... 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy.more suppliers
In PLoS ONE, 2004
... The mAbs against mouse CD3, CD28, IL-4, IL-5, IL-13, TNFα, IL-6, IL-8, IFN-γ and IL-10 ELISA kits were purchased from Biolegend (California, USA) ...
miRNA-Regulated Key Components of Cytokine Signaling Pathways and Inflammation in Rheumatoid Arthritis.
Ch'unch'ŏn, South Korea. In Med Res Rev, Feb 2016
Moreover, we have tried to portray the role of various miRNAs in different cytokines such as TNF-α, IL-1, IL-6, IL-10, IL-17, IL-18, IL-21, and granulocyte macrophage colony-stimulating factor (GMCSF).
Changes of synapses in experimental autoimmune encephalomyelitis by using Fasudil.
Datong, China. In Wound Repair Regen, Feb 2016
Neurotrophic factor BDNF and GDNF as well as immunomodulatory cytokine IL-10 in spinal cord were elevated in Fasudil-treated mice, while inflammatory cytokine IL-17, IL-1β, IL-6 and TNF-⟨ were obviously inhibited, accompanied by the decrease of inflammatory M1 iNOS and the increase of anti-inflammatory M2 Arg-1, providing a microenvironment that contributes to synaptic protection.
Effect of yeast-derived products and distillers dried grains with solubles (DDGS) on antibody-mediated immune response and gene expression of pattern recognition receptors and cytokines in broiler chickens immunized with T-cell dependent antigens.
Winnipeg, Canada. In Poult Sci, Feb 2016
On d 35, 5 birds per treatment were euthanized and the tissue samples from the cecal tonsils were collected to assess the gene expression of toll-like receptors TLR2b, TLR4, and TLR21, monocyte mannose receptor (MMR), and cytokines IL-10, IL-13, IL-4, IL-12p35, and IFN-γ.
Decidual Control of Trophoblast Invasion.
Mumbai, India. In Am J Reprod Immunol, Feb 2016
The decidual secretions contain high amounts of pro-invasive factors that include IL-1β, IL-5, IL-6, IL-7, IL-8, IL-9, IL-13, IL-15, Eotaxin CCL11, IP-10 and RANTES, and anti-invasive factors IL-10, IL-12 and VEGF.
B cells with regulatory properties in transplantation tolerance.
Nantes, France. In World J Transplant, Jan 2016
These cells act by multiple mechanisms such as secretion of immuno-suppressive cytokines interleukin-10 (IL-10) or IL-35, cytotoxicity, expression of inhibitory receptors or by secretion of non-inflammatory antibodies.
The ubiquitous hyaluronan: Functionally implicated in the oviduct?
Linköping, Sweden. In Theriogenology, Jan 2016
Hyaluronan is also present in the seminal plasma, and evidence points toward an involvement of hyaluronan and its receptor in the local (tubal and possibly uterine) production of antiinflammatory cytokines, such as interleukin-10, pertaining maternal immune tolerance of these foreign cells.
Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses.
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Buenos Aires, Argentina. In Cell, Oct 2015
Melatonin induces the expression of the repressor transcription factor Nfil3, blocking the differentiation of pathogenic Th17 cells and boosts the generation of protective Tr1 cells via Erk1/2 and the transactivation of the IL-10 promoter by ROR-α.