Small-molecule antagonists of Gli function
Bethesda, United States. In Unknown Journal, 2013
Hh signaling is normally initiated by the binding of Hh ligands (Shh, Ihh, and Dhh) to the 12TM Patched1 (Ptch1) receptor resulting in accumulation and activation of the G protein-coupled receptor-like protein Smoothened (Smo) within the primary cilium.
Hong Kong, Hong Kong. In Vitam Horm, 2011
The hedgehog family consists of sonic hedgehog (Shh), desert hedgehog (Dhh), and Indian hedgehog (Ihh).