Human Gm, Km, and Am allotypes and their molecular characterization: a remarkable demonstration of polymorphism.
Montpellier, France. In Methods Mol Biol, 2011
Gm-Am allotypes are inherited in fixed combinations, or Gm-Am haplotypes, owing to the linkage of the human IGHC genes (IGHG3, IGHG1, IGHA1, IGHG2, IGHG4, IGHE, and IGHA2 from 5' to 3' in the IGH locus on chromosome 14).
Multiple levels of analysis of an IGHG4 gene deletion.
Torino, Italy. In Hum Genet, 1990
In this paper, we report the characterization of a new type of deletion, involving the IGHG4 gene, in a subject who also carries a larger deletion of a previously described type on the second chromosome.
A human immunoglobulin IGHG3 allele (Gmb0,b1,c3,c5,u) with an IGHG4 converted region and three hinge exons.
Montpellier, France. In Immunogenetics, 1988
Moreover, we show that the LAT G3m (b0, b1, c3, c5, u) coding sequence results from the conversion, in the CH3 exon, of the G3m (b0, b1, b3, b4, b5, u, v) allele, the most frequent IGHG3 gene in the Negroid populations, by the homologous region of a IGHG4 gene.
Definition of the RFLP alleles in the human immunoglobulin IGHG gene locus.
Montpellier, France. In Eur J Immunol, 1988
Our data demonstrate that the restriction fragment length polymorphism is occasionally due to the presence or absence of a given restriction site as a consequence of a point mutation, such as the creation of an Eco RI site, at the codon 3 of exon 2 in one IGHG4 allele (IGHG4*D2).