IGF binding protein 5
Pappa2 deletion in mice affects male but not female fertility.
Canada. In Reprod Biol Endocrinol, 2014
BACKGROUND: Recent studies have found associations between the gene encoding pregnancy associated plasma protein-A2 (PAPP-A2), a protease of insulin-like growth factor binding protein -5 (IGFBP-5), and measures of female reproductive performance in cattle.
[Neuromuscular system and aging: involutions and implications].
Tarbes, France. In Geriatr Psychol Neuropsychiatr Vieil, 2013
The activity of the protein kinase (Akt) that stimulates the synthesis of regulation proteins (mTOR, p70S6, IGFBP-5) declines whereas the factors of degradation of proteins (NF-kappa B) are activated.
An ocular view of the IGF-IGFBP system.
Gainesville, United States. In Growth Horm Igf Res, 2013
IGFBP-5 has recently been linked to mediating fibrosis in proliferative vitreoretinopathy but also reduces neovascularization.
Growth hormone and the insulin-like growth factor system in myogenesis.
Syracuse, United States. In Endocr Rev, 1996
The effects of IGFs are significantly modulated by IGFBPs secreted by myoblasts in serum-free medium, inhibitory IG-FBPs-4 and -6 are expressed and secreted by L6A1 myoblasts, while expression of IGFBP-5 rises dramatically as differentiation proceeds.