gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

CD79a molecule, immunoglobulin-associated alpha

IgA
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, IgM, HAD, AGE, V1a
Papers using IgA antibodies
A novel informatics concept for high-throughput shotgun lipidomics based on the molecular fragmentation query language.
Supplier
Martin Sally, In PLoS ONE, 2010
... Mouse Anti-mouse CD36 (552544) and the negative control mouse anti-mouse IgA (553476) were purchased from BD Pharmigen; rat anti-mouse CD204 (MCA1322) and the negative control rat anti-mouse g2b (MCA1125) were purchased from AbD Serotec.
Small G proteins as key regulators of pancreatic digestive enzyme secretion
Supplier
Tsukise A. et al., In European Journal of Histochemistry : EJH, 2008
... antibodies diluted in 0.01 M PBS (pH 7.3) against lysozyme (polyclonal, from rabbit) (Dako, Glostrup, Denmark), IgA (polyclonal, from rabbit) (Dako), lactoferrin (polyclonal, from rabbit) ...
Expression of endogenous antimicrobial peptides in normal canine skin
Supplier
Tsukise A. et al., In European Journal of Histochemistry : EJH, 2008
Then, they were incubated with primary antibodies diluted in 0.01 M PBS (pH 7.3) against IgA (polyclonal, from rabbit) (Dako), lysozyme (polyclonal, from rabbit) ...
Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
Supplier
Shattock Robin J. et al., In Vaccine, 2004
... Goat anti-mouse HRP-conjugated IgA and biotinylated goat anti-mouse IgA were obtained from AbD Serotec (UK) ...
CD36 is a sensor of diacylglycerides.
Supplier
Ojcius David, In PLoS ONE, 2004
... Anti-mouse CD36 (cat# 552554), FITC-anti-mouse IgA (cat# 559354), FITC-rat-IgG2b (cat# 556923), and mouse IgA (cat# 553476) were purchased from Pharmingen, BD Biosciences (San Diego, CA) ...
more suppliers
Papers on IgA
Detection of specific immunoglobulin E antibodies toward common airborne allergens, peanut, wheat, and latex in solvent/detergent-treated pooled plasma.
New
Kristoffersen et al., Bergen, Norway. In Transfusion, Feb 2016
STUDY DESIGN AND METHODS: Consecutive batches of S/D-plasma transfused during September 2014 through March 2015 were investigated for IgE, IgG, IgA IgM, C3, C4, haptoglobin, anti-nuclear antibodies (ANAs), and red blood cell (RBC) antibodies.
Histone deacetylase inhibitors attenuate P-aIgA1-induced cell proliferation and extracellular matrix synthesis in human renal mesangial cells in vitro.
New
Chen et al., Shanghai, China. In Acta Pharmacol Sin, Feb 2016
AIM: Aberrantly glycosylated IgA1 is a key factor in the pathogenesis of IgA nephropathy (IgAN).
Highlights of the 2015 ERA-EDTA Congress-glomerular diseases.
New
Floege, Aachen, Germany. In Nephrol Dial Transplant, Feb 2016
Topics covered include a European survey on renal biopsy practice and indications, the STOP-IgAN randomized controlled trial in patients with IgA-nephropathy, B-cell- targeting therapies in minimal change nephropathy and focal segmental glomerulosclerosis (FSGS), novel insights into the action of glucocorticosteroids in glomerular crescent and scar (FSGS) formation, the immunoproteasome in IgA-nephropathy, socio-economic factors and glomerular disease progression, glomerular CD80 (B7-1) expression in FSGS patients and aldosterone-antagonism in proteinuric renal diseases.
The mucosa-kidney axis in IgA nephropathy.
Review
New
Feehally et al., Aachen, Germany. In Nat Rev Nephrol, Jan 2016
UNASSIGNED: Links between IgA nephropathy (IgAN) and the mucosa have been recognized since the 1970s.
Intensive Supportive Care plus Immunosuppression in IgA Nephropathy.
New
Impact
STOP-IgAN Investigators et al., München, Germany. In N Engl J Med, Jan 2016
BACKGROUND: The outcomes of immunosuppressive therapy, when added to supportive care, in patients with IgA nephropathy are uncertain.
Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells.
New
Park et al., Taejŏn, South Korea. In Immune Netw, Dec 2015
RGE slightly reduced B cell proliferation, but increased IgA production by LPS-stimulated B cells.
Molecular Insights into the Pathogenesis of IgA Nephropathy.
Review
New
Monteiro et al., Paris, France. In Trends Mol Med, Dec 2015
Immunoglobulin IgA nephropathy (IgAN) is the leading form of primary glomerulonephritis associated with end-stage renal failure, requiring either dialysis or renal transplantation.
Developments in the production of mucosal antibodies in plants.
Review
New
Schiermeyer et al., Aachen, Germany. In Biotechnol Adv, Dec 2015
Plant cells are able to produce high-quality mucosal antibodies as shown by the successful expression of the secretory immunoglobulins A (IgA) and M (IgM) in various antibody formats in different plant species including tobacco and its close relative Nicotiana benthamiana, maize, tomato and Arabidopsis thaliana.
IgA as therapeutic antibody.
Review
New
Leusen, Utrecht, Netherlands. In Mol Immunol, Nov 2015
This review is focused on the promises of IgA as a new therapeutic antibody.
Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.
New
Impact
Bendelac et al., Chicago, United States. In Immunity, Oct 2015
Immunoglobulin A (IgA) is prominently secreted at mucosal surfaces and coats a fraction of the intestinal microbiota.
Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial.
New
Impact
RAPID Trial Study Group et al., Toronto, Canada. In Lancet, Aug 2015
We excluded patients if they had undergone, or were on the waiting list to undergo, lung transplantation, lobectomy, or lung volume-reduction surgery, or had selective IgA deficiency.
Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy.
New
Impact
Karin et al., San Diego, United States. In Nature, Jun 2015
The crucial immunosuppressive B cells are plasmocytes that express IgA, interleukin (IL)-10 and programmed death ligand 1 (PD-L1), the appearance of which depends on TGFβ receptor signalling.
Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: the Pre-POINT randomized clinical trial.
New
Impact
Pre-POINT Study Group et al., München, Germany. In Jama, May 2015
MAIN OUTCOMES AND MEASURES: An immune response to insulin, measured as serum IgG and saliva IgA binding to insulin, and CD4+ T-cell proliferative responses to insulin.
Immunosuppression - tough ally in torrid time.
Review
Fol et al., Łódź, Poland. In Postepy Hig Med Dosw (online), 2014
This is related to the variable levels of deficiency for each antibody class (IgG, IgM, IgA) and a decrease in the number and function of immune cells, mainly T cells which results in the inhibition of cytokine production, signaling transduction and clonal expansion.
Association between the AGTR1 A1166C polymorphism and risk of IgA nephropathy: a meta-analysis.
Wang et al., Jinan, China. In Genet Mol Res, 2014
Numerous studies have evaluated the association between the A1166C polymorphism in the angiotensin II type 1 receptor (AGTR1) gene and immunoglobulin A nephropathy (IgAN) risk.
The mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.
GeneRIF
Malone et al., United States. In Mol Biol Rep, 2012
The mouse B cell-specific mb-1 gene encodes an immunoreceptor tyrosine-based activation motif (ITAM) protein that may be evolutionarily conserved in diverse species by purifying selection.
Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments.
Impact
GeneRIF
Pierce et al., Rockville, United States. In Nat Immunol, 2011
endocytosed BCR sequentially regulates MAPK and Akt signaling pathways from intracellular compartments
Interaction of human, rat, and mouse immunoglobulin A (IgA) with Staphylococcal superantigen-like 7 (SSL7) decoy protein and leukocyte IgA receptor.
GeneRIF
Hogarth et al., Melbourne, Australia. In J Biol Chem, 2011
Glycosylation of the CH2/CH3 interface inhibits interaction with the pathogen IgA binding protein SSL7, while maintaining binding of pIgR, essential to the biosynthesis and transport of SIgA.
Protein kinase C inhibitor sotrastaurin selectively inhibits the growth of CD79 mutant diffuse large B-cell lymphomas.
GeneRIF
Stegmeier et al., Cambridge, United States. In Cancer Res, 2011
STN produced significant antitumor effects in a mouse xenograft model of CD79A/B-mutated DLBCL.
[Aberrant glycosylation of immunoglobulin A and renal disease].
GeneRIF
Asano, In Tanpakushitsu Kakusan Koso, 2008
Aberrant glycosylation of immunoglobulin A causes IGA nephropathy. (review)
More papers using IgA antibodies
Korean Multi-center Cancer Cohort Study including a Biological Materials Bank (KMCC-I)
Supplier
Yoo K-Y et al., In British Journal of Cancer, 2001
... (VCA) IgG (EBV VCA IgG; Zeus Scientific, Raritan, NJ, USA), EBV VCA IgA (EBV VCA IgA; IBL, Hamburg, Germany), EBV nuclear ...
Detection of the complement degradation product C4d in renal allografts: Diagnostic and therapeutic implications
Supplier
Dakshina Murthy K. V. et al., In Indian Journal of Nephrology, 2001
... IF was performed in all biopsies with IgM, IgA, IgG, C3, C1q, kappa, lambda.Immunostaining with C4d was done on paraffin-embedded sections by polymer-Horse Radish Peroxidase (HRP) technique using polyclonal antiserum to C4d (Biogenex, India) ...
Coordinate induction of the actin cytoskeletal regulatory proteins gelsolin, vasodilator-stimulated phosphoprotein, and profilin during capillary morphogenesis in vitro
Supplier
Jung I. et al., In European Journal of Histochemistry : EJH, 1998
... For immunohistochemical staining we used the monoclonal anti-Mena antibody, isotype mouse IgA, clone 21 (BD Biosciences, Sparks, MD, USA) which ...
share on facebooktweetadd +1mail to friends