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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 25 Jan 2016.

Interferon, gamma

IFN-gamma
This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009] (from NCBI)
Top mentioned proteins: IL-4, IL-10, CAN, Interleukin-2, Interleukin-6
Papers using IFN-gamma antibodies
Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.
Supplier
Nixon Douglas F., In PLoS ONE, 2009
... IFNgamma ELISA antibody pairs were purchased from eBioscience.
Papers on IFN-gamma
Control of B cell lymphoma by therapeutic vaccination and acquisition of immune resistance is independent of direct tumor IFN-gamma signaling.
New
Mattarollo et al., Brisbane, Australia. In Immunol Cell Biol, 20 Feb 2016
UNASSIGNED: Immunomodulatory therapies can effectively control haematological malignancies by promoting anti-tumour immunity.
Designing anti-diabetic β-cells microcapsules using polystyrenic sulfonate, polyallylamine and a tertiary bile acid: Morphology, bioenergetics and cytokine analysis.
New
Al-Salami et al., Perth, Australia. In Biotechnol Prog, 09 Feb 2016
IFN-gamma (p<0.01) and IL-6 (p<0.01)
Mycobacterium leprae-Infected Macrophages Preferentially Primed Regulatory T Cell Responses and Was Associated with Lepromatous Leprosy.
New
Jing et al., Shanghai, China. In Plos Negl Trop Dis, 31 Jan 2016
When incubating with naive T cells, macrophages treated with live M. leprae preferentially primed regulatory T (Treg) cell responses with elevated FoxP3 and IL-10 expression, while interferon gamma (IFN-gamma) expression and CD8+ T cell cytotoxicity were reduced.
The Role of Type I Interferon Subtypes and Interferon-Gamma in Type I Interferon Diabetes Inhibitory Activity in the NOD Mouse.
New
Pontzer et al., Colombia. In J Interferon Cytokine Res, 30 Jan 2016
We hypothesize that type I IFN activity differs by IFN subtype and interaction with IFN-gamma.
Human kidney damage in fatal dengue hemorrhagic fever results of glomeruli injury mainly induced by IL17.
New
Duarte et al., São Paulo, Brazil. In J Clin Virol, 23 Jan 2016
Cells expressing IL17 and IL18+ cytokines predominated in the renal tissues, while IL4, IL6, IL10, IL13, TNF-alpha and IFN-gamma were rarely visualized.
Requirement of MyD88 signaling in keratinocytes for Langerhans cell migration and initiation of atopic dermatitis-like symptoms in mice.
New
Weighardt et al., Bonn, Germany. In Eur J Immunol, 23 Jan 2016
Moreover, production of IFN-gamma, IL-17 and CCL17 was reduced in skin-draining lymph node (sdLN) cells and OVA-specific immunoglobulin levels were lower in MyD88-deficient mice.
Signaling, stress response and apoptosis in pre-diabetes and diabetes: restoring immune balance in mice with alloxan-induced type 1 diabetes mellitus.
New
Fesenko et al., Moscow, Russia. In Int Immunopharmacol, 12 Jan 2016
Pre-diabetes resulted in a decrease in IL-4, IL-5 and IL-10 in plasma; in diabetic mice, plasma IFN-gamma, IL-6, TNF-alpha, and IL-10 were decreased.
IL-17 promoted the inhibition of medulloblastoma in mice by splenocyte injection.
Wang et al., Shanghai, China. In Eur J Med Res, 2014
Meanwhile, the IL-17, IL-6, IL-23, Ccl2, Ccl20 and IFN-gamma expression in the tumors was also examined by real-time PCR, Western blot and enzyme-linked immunosorbent assay.
Effects of acupuncturing Pishu combined with Ginsenoside Rg3 on the immune function of rats with chronic fatigue.
Chen et al., Shenyang, China. In Int J Clin Exp Med, 2014
Serum IFN-gamma (IFN-γ) and IL-4 contents were detected by ELISA.
Role of Baicalin in Anti-Influenza Virus A as a Potent Inducer of IFN-Gamma.
Wang et al., Beijing, China. In Biomed Res Int, 2014
Baicalin (BA) is a flavonoid compound purified from Scutellaria baicalensis Georgi and has been shown to possess a potent inhibitory activity against viruses.
Negative impact of IFN-γ on early host immune responses to retroviral infection.
GeneRIF
Kassiotis et al., Hamilton, United States. In J Immunol, 2012
In a model of lactate dehydrogenase-elevating virus (LDV) and Friend virus coinfection, IFN-gamma production can have detrimental effects on early adaptive immune responses and virus control.
CD4+ T cell-dependent IFN-γ production by CD8+ effector T cells in Mycobacterium tuberculosis infection.
GeneRIF
Ernst et al., New York City, United States. In J Immunol, 2012
IFN-gamma production by CD8-positive effector T cells is influenced by CD4-positive T cells at the site of Mycobacterium tuberculosis infection in mice.
Cutting edge: influence of Tmevpg1, a long intergenic noncoding RNA, on the expression of Ifng by Th1 cells.
GeneRIF
Aune et al., Nashville, United States. In J Immunol, 2012
Tmevpg1 expression contributes to, but alone is not sufficient to, drive T helper(Th)1-cell dependent IFN-gamma expression.
NK cells regulate CD8+ T cell priming and dendritic cell migration during influenza A infection by IFN-γ and perforin-dependent mechanisms.
GeneRIF
Kemeny et al., Singapore, Singapore. In J Immunol, 2012
IFN-gamma produced by natural killer (NK) cells is crucial for dendritic- and T-cell recruitment to the posterior mediastinal lymph node.
[Changes to IFN-γ and IP-10 in the arterial blood of premature infants before and after mechanical ventilation].
GeneRIF
Wang et al., Chengdu, China. In Zhongguo Dang Dai Er Ke Za Zhi, 2012
Serum IFN-gamma and IP-10 levels increase after mechanical ventilation, suggesting that both may participate in the immune-inflammatory process of ventilation-induced lung injury.
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.
Impact
Kemper et al., London, United Kingdom. In Nat Immunol, 2010
Furthermore, CD4(+) T cells in rheumatoid arthritis failed to switch, consequently producing excessive interferon-gamma (IFN-gamma).
Interleukin-23 drives intestinal inflammation through direct activity on T cells.
Impact
Powrie et al., Oxford, United Kingdom. In Immunity, 2010
Through direct signaling into T cells, IL-23 drove intestinal T cell proliferation, promoted intestinal Th17 cell accumulation, and enhanced the emergence of an IL-17A(+)IFN-gamma(+) population of T cells.
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis.
Impact
O'Garra et al., London, United Kingdom. In Nature, 2010
Modular and pathway analysis revealed that the TB signature was dominated by a neutrophil-driven interferon (IFN)-inducible gene profile, consisting of both IFN-gamma and type I IFN-alphabeta signalling.
Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.
Impact
Caligiuri et al., Columbus, United States. In Immunity, 2010
In the absence of IL-1beta, a substantially greater fraction of IL-1R1(hi) iNK cells differentiated to stage 4 NK cells and acquired the ability to kill and secrete IFN-gamma.
An IL-1beta-dependent switch in innate mucosal immunity?
Impact
Di Santo, Paris, France. In Immunity, 2010
The mechanisms that guide the development of mucosal-associated innate lymphoid cells (ILCs) producing IL-17, IL-22, and IFN-gamma are the subject of intense interest.
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