gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Immediate early response 5

IER5, immediate early response 5
This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on IER5
Transcriptional repression of Cdc25B by IER5 inhibits the proliferation of leukemic progenitor cells through NF-YB and p300 in acute myeloid leukemia.
Yamashita et al., Hamamatsu, Japan. In Plos One, 2010
Transcriptional repression mediated by IER5 regulates Cdc25B expression levels via the release of NF-YB and p300 in acute myeloid leukemia.
Induced expression of the IER5 gene by gamma-ray irradiation and its involvement in cell cycle checkpoint control and survival.
Zhou et al., Beijing, China. In Radiat Environ Biophys, 2009
the early radiation-induced expression of IER5 affects radiosensitivity via disturbing radiation-induced cell cycle checkpoints
Gene expression in the brain across the sleep-waking cycle.
Tononi et al., San Diego, United States. In Brain Res, 2001
Studies in rat found higher mRNA levels after waking and sleep deprivation for immediate early genes/transcription factors such as IER5
share on facebooktweetadd +1mail to friends