JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD
In British Journal of Cancer, 2003
... (C-17) antibody (Santa Cruz Biotechnology), monoclonal mouse anti-vinculin (Sigma, St Louis, MO, USA), polyclonal rabbit anti-DFF45 (BD Biosciences, San Diego, CA, USA), ...
Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue.
Boston, United States. In Circ Heart Fail, Jan 2016
In HFpEF, despite a larger brown AT mass (5.96 versus 4.50 mg/g), brown AT showed reduced activity with decreased uncoupling protein 1 (ucp-1), cell death-inducing DFFA-like effector a (cidea), and epithelial V-like antigen (eva) expression and decreased expression of lipolytic enzymes (hormone-sensitive lipase, lipoprotein lipase, and fatty acid binding protein 4) versus sham.
The role of peptidylarginine deiminase 4 in ovarian cancer cell tumorigenesis and invasion.
Jinan, China. In Tumour Biol, Dec 2015
PCR arrays of A2780 cells treated with PADI4-siRNA revealed the up-regulated expression of six genes, including cell death-inducing DFFA-like effector a (CIDEA) and tumor necrosis factor receptor superfamily member 9 (TNFRSF9), and the down-regulation of seven genes, including integrin beta 3 (ITGB3) and BCL2-antagonist/killer 1 (BAK1).
Lipid droplet metabolism.
Stanford, United States. In Curr Opin Clin Nutr Metab Care, 2013
Cell death-inducing DFF45-like effector proteins are not only involved in lipid droplet expansion, but also in the cellular response to stress and lipid secretion.
DFF45 expression in ovarian endometriomas.
Kraków, Poland. In Eur J Obstet Gynecol Reprod Biol, 2009
A decreased level of DFF45 observed in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.