ShcC proteins: Brain aging and beyond.
Beersheba, Israel. In Ageing Res Rev, 24 Dec 2014
UNLABELLED: To date, most studies of Shc family of signaling adaptor proteins have been focused on the near-ubiquitously expressed ShcA, indicating its relevance to age-related diseases and longevity.
The role of heat shock proteins in atherosclerosis.
Innsbruck, Austria. In Nat Rev Cardiol, Sep 2014
These T cells recognize heat shock protein (HSP)60, which is expressed together with adhesion molecules by endothelial cells in response to classic risk factors for atherosclerosis.
Emerging role of protein kinase C in energy homeostasis: A brief overview.
Columbus, United States. In World J Diabetes, Jul 2014
Available data support the model in which PKCβ functions as a "diet-sensitive" metabolic sensor whose induction in adipose tissue by high-fat diet is among the initiating event disrupting mitochondrial homeostasis via intersecting with p66(Shc) signaling to amplify adipose dysfunction and have systemic consequences.
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
More papers using
Oxford, United Kingdom. In Nature, 2012
analysis of multiple sclerosis GWAS data in conjunction with the 1000 Genomes Project data, shows genetic evidence that strongly implicates SNP rs1800693 as the causal variant in the TNFRSF1A region; further functional studies show that this MS risk allele directs expression of a novel, soluble form of TNFR1 that can block TNF
Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10–a role for IL-1 beta?
In Journal of Neuroinflammation, 2003
... anti-phospho-JAK1, anti-phospho-STAT1, STAT1, anti-phospho-IκBα and anti-SOCS3 (Cell Signalling, Danvers, MA, USA), anti-phospho-c-jun and anti-TNFα receptor (TNFR1) (Santa Cruz Biotechnology, Heidelberg, Germany, and anti-actin ...