Sublingual Vaccine with GroEL Attenuates Atherosclerosis.
Oral, Kazakhstan. In J Dent Res, 19 Mar 2014
UNLABELLED: Autoimmune responses to heat-shock protein 60 (HSP60) contribute to the progression of atherosclerosis, whereas immunization with HSP60 may induce atheroprotective responses.
Chaperone machines for protein folding, unfolding and disaggregation.
London, United Kingdom. In Nat Rev Mol Cell Biol, Oct 2013
The structural basis of their mechanism of action is being unravelled (in particular for the heat shock proteins HSP60, HSP70, HSP90 and HSP100) and typically involves massive displacements of 20-30 kDa domains over distances of 20-50 Å and rotations of up to 100°.
Innate and Adaptive Responses to Heat Shock Proteins in Behcet's Disease.
İstanbul, Turkey. In Genet Res Int, 2012
60-kD HSP (HSP60) is also shown to be recognized by pattern recognition receptors such as toll-like receptors (TLR) and is suggested to be an endogenous "danger" signal to the immune system with rapid inflammatory cytokine releases and enhancement of adaptive Th1-type responses.
Sam68 interacts with IRS1.
More papers using
Sevilla, Spain. In Biochem Pharmacol, 2012
Sam68 interacts with insulin receptor substrate (IRS)-1 in basal conditions, and insulin increases the affinity between these two partners.
Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10–a role for IL-1 beta?
In Journal of Neuroinflammation, 2003
... anti-phospho-JAK1, anti-phospho-STAT1, STAT1, anti-phospho-IκBα and anti-SOCS3 (Cell Signalling, Danvers, MA, USA), anti-phospho-c-jun and anti-TNFα receptor (TNFR1) (Santa Cruz Biotechnology, Heidelberg, Germany, and anti-actin ...