Profiling signaling proteins in human spermatozoa: biomarker identification for sperm quality evaluation.
Aveiro, Portugal. In Fertil Steril, 22 Aug 2015
RESULT(S): The results indicated that the phosphorylated levels of several proteins (Bad, GSK-3β, HSP27, JNK/SAPK, mTOR, p38 MAPK, and p53), as well as cleavage of PARP (at D214) and Caspase-3 (at D175), were significantly correlated with motility parameters.
HSP27, 70 and 90, anti-apoptotic proteins, in clinical cancer therapy (Review).
Nanjing, China. In Int J Oncol, Jul 2014
Among the heat shock proteins (HSP), HSP27, HSP70 and HSP90 are the most studied stress-inducible HSPs, and are induced in response to a wide variety of physiological and environmental insults, thus allowing cells to survive to lethal conditions based on their powerful cytoprotective functions.
Melatonin influences pancreatic cancerogenesis.
Kraków, Poland. In Histol Histopathol, Apr 2014
On the contrary, low concentrations of melatonin turn on the production of anti-apoptotic heat shock proteins: HSP27, HSP70, and HSP90, which prevents the activation of caspase-3.
Prognostic biomarkers in patients with resected cholangiocarcinoma: a systematic review and meta-analysis.
Amsterdam, Netherlands. In Ann Surg Oncol, Feb 2014
Other markers showed promising results in single studies, including HSP27, Akt, HDGF, MUC6, p16, p-4EBP1, S100A4, α-SMA, Keratin 903, and TROP2.
Large potentials of small heat shock proteins.
More papers using
Moscow, Russia. In Physiol Rev, 2011
Ubiquitously expressed HSPB1 (HSP27) is involved in the control of protein folding and, when mutated, plays a significant role in the development of certain neurodegenerative disorders.