Mitochondrial dynamics and inherited peripheral nerve diseases.
Milano, Italy. In Neurosci Lett, Jul 2015
Microtubules, neurofilaments, and chaperones such as heat shock proteins (HSPs) also have a fundamental role in mitochondrial transport and mutations in some of related encoding genes cause peripheral neuropathy (TUBB3, NEFL, HSPB1, HSPB8, HSPB3, DNAJB2).
Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8.
Lyon, France. In Int J Hyperthermia, 2013
AIMS: To understand the functions of the stress-inducible members of the sHSP family, HspB1, HspB5 and HspB8, and be able to therapeutically modulate their activities, researchers are faced with the complex oligomerisation and phosphorylation properties of these proteins and with their ability to interact with each other and with specific protein targets.