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Nuclear transcription factor Y, gamma

This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] (from NCBI)
Top mentioned proteins: CAN, Histone, ACID, HAD, V1a
Papers using HSM antibodies
Adaptation and the cost of complexity
Collins Sinéad, In Proceedings of the Royal Society B: Biological Sciences, 1999
... contents of all wells from a single plate were pooled, diluted with sterile high salt media (HSM), New England BioLabs and then pipetted into ...
Papers on HSM
Functional conservation of rice OsNF-YB/YC and Arabidopsis AtNF-YB/YC proteins in the regulation of flowering time.
Kim et al., Seoul, South Korea. In Plant Cell Rep, Feb 2016
Plant NUCLEAR FACTOR Y (NF-Y) transcription factors play important roles in plant development and abiotic stress.
A Phylogenetically Conserved Group of Nuclear Factor-Y Transcription Factors Interact to Control Nodulation in Legumes.
Niebel et al., Orsay, France. In Plant Physiol, Dec 2015
NF-YA TFs interact with NF-YB and NF-YC subunits to regulate target genes containing the CCAAT box consensus sequence.
QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions.
Wurtele et al., Ames, United States. In Proc Natl Acad Sci U S A, Dec 2015
We determine that QQS protein binds to the transcriptional regulator AtNF-YC4 (Arabidopsis nuclear factor Y, subunit C4).
Constitutive overexpression of the TaNF-YB4 gene in transgenic wheat significantly improves grain yield.
Lopato et al., Adelaide, Australia. In J Exp Bot, Nov 2015
In this work, a number of genes encoding NF-YB and NF-YC subunits were isolated from drought-tolerant wheat (Triticum aestivum L. cv.
The overexpression of an Amaranthus hypochondriacus NF-YC gene modifies growth and confers water deficit stress resistance in Arabidopsis.
Délano-Frier et al., Irapuato, Mexico. In Plant Sci, Nov 2015
Nuclear factor-Y (NF-Y), is a plant heterotrimeric transcription factor constituted by NF-YA, NF-YB and NF-YC subunits.
Epigenetic role of CCAAT box-binding transcription factor NF-Y on ID gene family in human embryonic carcinoma cells.
Shahhoseini et al., Tehrān, Iran. In Iubmb Life, Nov 2015
Nuclear factor Y (NF-Y) is a histone substitute protein that specifically binds to the CCAAT box of the target genes and thereby promotes their regulation.
Alleviating effect of Mallotus roxburghianus in heat-induced testicular dysfunction in Wistar rats.
Gurusubramanian et al., Āīzawl, India. In Pharm Biol, Nov 2015
MATERIALS AND METHODS: Scrotal hyperthermia experiments were performed in three groups (n = 7 per group) consisting of (i) the control group (C) maintained at 22 °C for 30 min, (ii) the heat stress-induced group (HS), and (iii) the heat stress-induced M. roxburghianus-treated group (HSM - 400 mg/kg each) in a thermostatically controlled water bath at 43 °C for 30 min.
Identification and expression profile analysis of NUCLEAR FACTOR-Y families in Physcomitrella patens.
He et al., Beijing, China. In Front Plant Sci, 2014
NUCLEAR FACTOR Y transcription factors belong to a multimember family and consist of NF-YA/B/C subunits.
Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo.
Chong et al., San Francisco, United States. In Sci Rep, 2014
Hirsutella sinensis mycelium (HSM), the anamorph of Cordyceps sinensis, is a traditional Chinese medicine that has been shown to possess various pharmacological properties.
Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination.
Mantovani et al., Milano, Italy. In Cell, 2013
NF-Y is composed of the NF-YA and NF-YB/NF-YC subunits, the latter two hosting histone-fold domains (HFDs).
The promiscuous life of plant NUCLEAR FACTOR Y transcription factors.
Mantovani et al., Milano, Italy. In Plant Cell, 2012
The CCAAT box is one of the most common cis-elements present in eukaryotic promoters and is bound by the transcription factor NUCLEAR FACTOR Y (NF-Y).
NF-Y and the transcriptional activation of CCAAT promoters.
Mantovani et al., Milano, Italy. In Crit Rev Biochem Mol Biol, 2012
NF-Y consists of three evolutionarily conserved subunits: a dimer of NF-YB and NF-YC which closely resembles a histone, and the "innovative" NF-YA.
Gene expression of the tumour suppressor LKB1 is mediated by Sp1, NF-Y and FOXO transcription factors.
Rösl et al., Heidelberg, Germany. In Plos One, 2011
Sp1, NF-Y and FOXO transcription factors are involved in the regulation of LKB1 transcription.
NF-Y is essential for expression of the proapoptotic bim gene in sympathetic neurons.
Ham et al., London, United Kingdom. In Cell Death Differ, 2011
NF-Y cooperates with FOXO3a to recruit CBP/p300 to the bim promoter to form a stable multi-protein/DNA complex that activates bim transcription after survival factor withdrawal.
NF-YC functions as a corepressor of agonist-bound mineralocorticoid receptor.
Itoh et al., Tokyo, Japan. In J Biol Chem, 2010
NF-YC functions as a new corepressor of agonist-bound mineralocorticoid receptor via alteration of aldosterone-induced MR conformation
NF-YC complexity is generated by dual promoters and alternative splicing.
Mantovani et al., Milano, Italy. In J Biol Chem, 2010
NF-YC complexity is generated by dual promoters and alternative splicing
Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers.
Kotani et al., Tsukuba, Japan. In Genomics, 2009
Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple neoplasms.
Coordinate control of synaptic-layer specificity and rhodopsins in photoreceptor neurons.
Zipursky et al., Los Angeles, United States. In Nature, 2009
Repression is dependent on NF-YC, a subunit of the NF-Y (nuclear factor Y) transcription factor.
Sonicated human serum microspheres
Cheng, Bethesda, United States. In Unknown Journal, 2006
Sonicated human serum microspheres (HSM) is a preparation of air-filled HSM that was developed as an ultrasound (US) contrast agent for use in echocardiography to enhance US images (1).
Role of the CCAAT-binding protein CBF/NF-Y in transcription.
de Crombrugghe et al., Houston, United States. In Trends Biochem Sci, 1998
In each CBF subunit, the segment needed for formation of the CBF-DNA complex is conserved from yeast to human and, interestingly, the conserved segment of two CBF subunits, CBF-A and CBF-C, are homologous to the histone-fold motif of eukaryotic histones and archaebacterial histone-like protein HMf-2.
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