[Analysis of gastric cancer tissues genome methylation by DNA methylation chip].
Zhangjiakou, China. In Zhonghua Wei Chang Wai Ke Za Zhi, Nov 2015
In the CpG islands, 123 significantly different methylated genes were identified in gastric cancer tissues, such as WNT2B, JAK2 and TPT1, while 139 significantly different methylated genes were identified in their matched adjacent tissues, such as TNFRSF4, HOXC8 and NFYA.
Regulation of TGF-beta signaling by Smad7.
Beijing, China. In Acta Biochim Biophys Sin (shanghai), 2009
Besides, these inhibitory Smad proteins also inhibit TGF-beta/BMP signaling in the nucleus by interacting with transcriptional repressors, such as histone deacetylases, Hoxc-8, and CtBP, or disrupting the formation of the TGF-beta-induced functional Smad-DNA complexes.
Specification of motoneurons from human embryonic stem cells.
In Nat Biotechnol, 2005
The in vitro-generated motoneurons expressed HB9, HoxC8, choline acetyltransferase and vesicular acetylcholine transporter, induced clustering of acetylcholine receptors in myotubes, and were electrophysiologically active.
MicroRNA-directed cleavage of HOXB8 mRNA.
Cambridge, United States. In Science, 2004
We find that miR-196, a miRNA encoded at three paralogous locations in the A, B, and C mammalian HOX clusters, has extensive, evolutionarily conserved complementarity to messages of HOXB8, HOXC8, and HOXD8.
[The role of Smads and related transcription factors in the signal transduction of bone morphogenetic protein inducing bone formation].
Shanghai, China. In Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2003
Smad1 and Smad5 related with transcription factors included core binding factor A1 (CBFA1), smad-interacting protein 1 (SIP1), ornithine decarboxylase antizyme (OAZ), activating protein-1 (AP-1), xenopus ventralizing homeobox protein-2 (Xvent-2), sandostatin (Ski), antiproliferative proteins (Tob), and homeodomain-containing transcriptian factor-8 (Hoxc-8), et al.