Establishment of a predictive genetic model for estimating chemotherapy sensitivity of colorectal cancer with synchronous liver metastasis.
Fuzhou, China. In Cancer Biother Radiopharm, 2013
Seven candidate genes (NKX2-3, FXYD6, TGFB1I1, ACTG2, ANPEP, HOXB8, and KLK11), which exhibited positive or negative correlations, were incorporated into a genetic model, with an overall accurate predication rate of 93.3%.
Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots.
Boston, United States. In J Clin Endocrinol Metab, 2013
Most notably, gene ontology and pathway analysis identified homeobox genes (HOXA2, HOXA3, HOXA4, HOXA5, HOXA9, HOXB7, HOXB8, HOXC8, and IRX2) that were down-regulated in the gluteal depot in both sexes (P = 2 × 10(-10)).
MicroRNA-directed cleavage of HOXB8 mRNA.
Cambridge, United States. In Science, 2004
RNA fragments diagnostic of miR-196-directed cleavage of HOXB8 were detected in mouse embryos; results point to a miRNA-mediated mechanism for the posttranscriptional restriction of HOX gene expression during vertebrate development