Palmitic acid in the sn-2 position decreases glucose-dependent insulinotropic polypeptide secretion in healthy adults.
Maastricht, Netherlands. In Eur J Clin Nutr, 26 Apr 2014
The meals provided 14 g protein, 85 g carbohydrate and 50 g test fat, supplied as high oleic sunflower (HOS) oil (control), palm olein (PO), interesterified palm olein (IPO) and lard containing 0.6, 9.2, 39.1 and 70.5 mol% palmitic acid at sn-2, respectively.Results:No differences in plasma glucose, insulin and C-peptide response between meals were found.
SWI/SNF chromatin-remodeling complexes in cardiovascular development and disease.
Chapel Hill, United States. In Cardiovasc Pathol, 31 Mar 2014
Notably, multiple subunits of switching defective/sucrose non-fermenting (SWI/SNF) chromatin-remodeling complexes have been identified as strong candidates underlying these defects because they physically and functionally interact with cardiogenic transcription factors critical to cardiac development, such as TBX5, GATA-4, and NKX2-5.
Effects of diabetes on the eye.
Baltimore, United States. In Invest Ophthalmol Vis Sci, Dec 2013
Gene therapies upregulating MNNG HOS transforming gene (cMet) and/or downregulating MMP10 and cathepsin S are potential future therapies for diabetic keratopathy.
Alternative splicing of T-box transcription factor genes.
Birmingham, United States. In Biochem Biophys Res Commun, 2011
Currently, TBX3, TBX5, and TBX20 are TBX genes defined to have multiple protein isoforms created by alternative splicing and characterized by expression and functional studies.