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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

H6 homeobox 3

Hmx3, Nkx5.1, Nkx5, Nkx5-1
Top mentioned proteins: Hmx2, PAX2, FATE, CAN, BMP4
Papers on Hmx3
Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area.
Ferran et al., Murcia, Spain. In Brain Struct Funct, Aug 2015
In this report, we map descriptively the early differentiation and apparent migratory dispersion of mouse subpallial somatostatin-expressing (Sst) cells from E10.5 onward, comparing their topography with the expression patterns of the genes Dlx5, Gbx2, Lhx7-8, Nkx2.1, Nkx5.1 (Hmx3), and Shh, which variously label parts of the subpallium.
High throughput genomic screen identifies multiple factors that promote cooperative Wnt signaling.
Morrisey et al., Philadelphia, United States. In Plos One, 2012
This screen identified several homeobox factors including Msx2, Nkx5.2, and Esx1, in addition to other factors known to promote Wnt signaling including Pias4.
Mutation analysis of Netrin 1 and HMX3 genes in patients with superior semicircular canal dehiscence syndrome.
Gürtler et al., Aarau, Switzerland. In Acta Otolaryngol, 2012
CONCLUSION: In spite of its absence in the control population, there is questionable evidence for the alteration c.114C->T in the HMX3 gene being implicated in the development of superior semicircular canal dehiscence (SSCD).
The Nkx5/HMX homeodomain protein MLS-2 is required for proper tube cell shape in the C. elegans excretory system.
Sundaram et al., Philadelphia, United States. In Dev Biol, 2012
Here we show that the Nkx5/HMX homeodomain protein MLS-2 is required for cellular elongation and shape maintenance of two tubular epithelial cells in the C. elegans excretory system, the duct and pore cells.
Pivotal role of hmx2 and hmx3 in zebrafish inner ear and lateral line development.
Xu et al., London, United Kingdom. In Dev Biol, 2010
hmx3 acts as cell autonomous factors required redundantly for cell fate specification and differentiation during inner ear and lateral line development
Molecular (SNP) analyses of overlapping hemizygous deletions of 10q25.3 to 10qter in four patients: evidence for HMX2 and HMX3 as candidate genes in hearing and vestibular function.
Pevsner et al., Baltimore, United States. In Am J Med Genet A, 2009
propose that hemizygous deletions of HMX2 and HMX3 are responsible for inner ear malformations, vestibular dysfunction, and congenital sensorineural hearing loss
Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass.
Schimenti et al., Ithaca, United States. In Bmc Dev Biol, 2008
BACKGROUND: The H6 homeobox genes Hmx1, Hmx2, and Hmx3 (also known as Nkx5-3; Nkx5-2 and Nkx5-1, respectively), compose a family within the NKL subclass of the ANTP class of homeobox genes.
Identification of the minimal promoter region of the mouse NKX5-3, a transcription factor implicated in eye development.
Schorderet et al., Sion, Switzerland. In Gene, 2008
NKX5-3 is a homeobox transcription factor implicated in eye development.
Dan is required for normal morphogenesis and patterning in the developing chick inner ear.
Yokouchi et al., Kumamoto, Japan. In Dev Growth Differ, 2007
Although most of the patterning is regulated by extrinsic signals, it is not known how Nkx5.1 and Msx1 are patterned.
The homeodomain-containing transcription factor X-nkx-5.1 inhibits expression of the homeobox gene Xanf-1 during the Xenopus laevis forebrain development.
Zaraisky et al., Moscow, Russia. In Mech Dev, 2004
a role of stage-specific inhibitor of Xanf-1 in the anterior neural plate during the Xenopus development
Genomic organization and expression analysis of the murine Fam3c gene.
Greinwald et al., Cincinnati, United States. In Gene, 2004
Analysis of the Fam3c promoter region demonstrated a putative Nkx5.1 binding site.
The role of Six1 in mammalian auditory system development.
Xu et al., Great Falls, United States. In Development, 2003
Furthermore, loss of Six1 function alters the expression pattern of Nkx5.1 and Gata3, indicating that Six1 is required for regional specification of the otic vesicle.
An expanded domain of fgf3 expression in the hindbrain of zebrafish valentino mutants results in mis-patterning of the otic vesicle.
Riley et al., College Station, United States. In Development, 2002
Anterior markers pax5 and nkx5.1 are expressed in expanded domains that include the entire otic epithelium juxtaposed to the hindbrain, and the posterior marker zp23 is not expressed.
The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway.
Levi et al., Genova, Italy. In Dev Biol, 2002
In the Dlx5(-/-) embryos, no changes in expression of Nkx5.1(Hmx3),
The development of the vertebrate inner ear.
Giráldez et al., Madrid, Spain. In Mech Dev, 1998
The disruption of the mouse Brn3.1 gene identifies the first mutation affecting sensory hair-cell specification, and mutants for Pax2 and Nkx5.1 genes show their requirement for the development of specific regions of the otic vesicle.
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