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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

High mobility group box 1

HMGB1, p30, HMG1
heparin binding protein that facilitates neurite outgrowth [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, V1a, TLR4, Interleukin-6, RAGE
Papers using HMGB1 antibodies
Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1
Supplier
Singh Lalit P. et al., In Experimental Diabetes Research, 2010
... , pro-caspase-1, NLRP3 (cryopyrin), and HMGB1 are from Santa Cruz Biotechnology (Santa Cruz, CA), and ...
HMGB1 inhibitor glycyrrhizin attenuates intracerebral hemorrhage-induced injury in rats
Supplier
Shimohama Shun et al., In International Journal of Alzheimer's Disease, 2010
... 42; Anaspec, San Jose, CA) in the presence or absence of calf thymus-purified HMGB1 (WAKO Chemicals, Osaka, Japan) ...
Circulating mitochondrial DAMPs cause inflammatory responses to injury
Supplier
Lotze Michael T. et al., In The Journal of Cell Biology, 2009
... The antibodies to HMGB1 were obtained from Sigma-Aldrich and Novus Biologicals.
Genome-Wide Linkage Scan in Gullah-Speaking African American Families With Type 2 Diabetes
Supplier
Garvey W. Timothy et al., In Diabetes, 2007
... (Grant M01-RR-1070), by the Genetics Core Facility of the UAB Clinical Nutrition Research Unit (Grant P30-DK-56336), and by the South Carolina Center of Biomedical Research Excellence (COBRE) for ...
Calpain-mediated MPP+ toxicity in mitochondrial DNA depleted cells.
Supplier
Maedler Kathrin, In PLoS ONE, 2007
... A monoclonal antibody to HMGB1 was acquired from Abcam Inc ...
more suppliers
Papers on HMGB1
Beyond the grave: When is cell death critical for immunity to infection?
Review
New
Zychlinsky et al., Berlin, Germany. In Curr Opin Immunol, Feb 2016
Recent advances in the genetic manipulation of regulated cell death and danger-associated molecular patterns and 'alarmins', such as HMGB1 and the IL-1 family, may hold the key to delineating the consequences of cell death in immunity to infection.
Nongenomic actions of thyroid hormone.
Review
New
Leonard et al., Albany, United States. In Nat Rev Endocrinol, Feb 2016
p30 TRα1 is another shortened TR isoform found at the plasma membrane that binds T3 and mediates nongenomic hormonal effects in bone cells.
Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth.
New
Hassan et al., Detroit, United States. In Am J Reprod Immunol, Jan 2016
The aim of this study was to determine whether intra-amniotic administration of an alarmin, HMGB1, could induce preterm labor/birth.
DAMP and DIC: The role of extracellular DNA and DNA-binding proteins in the pathogenesis of DIC.
Review
New
Zeerleder et al., Hamilton, Canada. In Blood Rev, Jan 2016
histones and high mobility group box 1 protein [HMGB1]) are released into circulation.
High Mobility Group B Proteins, Their Partners, and Other Redox Sensors in Ovarian and Prostate Cancer.
Review
New
Cerdán et al., A Coruña, Spain. In Oxid Med Cell Longev, Dec 2015
High mobility group B (HMGB) proteins have been previously related to the onset and progressions of cancers of different origins.
Expression of the Receptor for Advanced Glycation End Products in Epicardial Fat: Link with Tissue Thickness and Local Insulin Resistance in Coronary Artery Disease.
New
Corsi Romanelli et al., Milano, Italy. In J Diabetes Res, Dec 2015
EAT expression of RAGE, GLUT4, adiponenctin, GLO1, HMGB1, TLR-4, and MyD88 was analyzed by microarray.
Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
New
Impact
Wu et al., Boston, United States. In Cell, Dec 2015
Induced asymmetry involving tilting of the nonamer-binding domain dimer of RAG1 upon binding of HMGB1-bent 12-RSS or 23-RSS underlies the molecular mechanism for the 12/23 rule.
[Effect of Qingyi Granule on HMGB1 Expression in Liver and Renal Tissues of Severe Acute Pancreatitis Rats].
New
Wang et al., In Zhongguo Zhong Xi Yi Jie He Za Zhi, Nov 2015
OBJECTIVE: To explore the effect of Qingyi Granule (QYG) on high mobility group box-1 (HMGB1) expressions in liver and renal tissues of severe acute pancreatitis (SAP) rats.
[Role of HMGB1 in Inflammatory-mediated Injury Caused by Digestive System Diseases and Its Repair].
Review
New
Xie et al., In Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, Aug 2015
High mobility group box 1 protein (HMGB1), a damage-associated molecular pattern, exists ubiquitously in the cells of mammals.
Barrier Epithelial Cells and the Control of Type 2 Immunity.
Review
New
Impact
Lambrecht et al., Gent, Belgium. In Immunity, Aug 2015
These ECs mount a prototypical response made up of chemokines, innate cytokines such as interleukin-1 (IL-1), IL-25, IL-33, and thymic stromal lymphopoietin (TSLP), as well as the alarmins uric acid, ATP, HMGB1, and S100 proteins.
Development and evaluation of a loop-mediated isothermal amplification assay for detection of Ehrlichia canis DNA in naturally infected dogs using the p30 gene.
Marins et al., Ribeirão Preto, Brazil. In Genet Mol Res, 2014
In this study, a loop-mediated isothermal amplification (LAMP) assay targeting the p30 gene of E. canis was developed.
PKR and HMGB1 expression and function in rheumatoid arthritis.
Rong et al., Shouguang, China. In Genet Mol Res, 2014
We aimed to examine the roles of double-stranded RNA-activated protein kinase (PKR) and high-mobility group box chromosomal protein 1 (HMGB1) in a rat model of RA.
Dendritic cells decide CD8(+) T cell fate.
Impact
Mowat, Glasgow, United Kingdom. In Immunity, 2014
(2014) propose that CD103(+) DCs in mouse lung selectively generate effector CD8(+) T cells by binding the alarmin HMGB1 via CD24 and presenting it to RAGE(+) T cells.
Distinct dendritic cell subsets dictate the fate decision between effector and memory CD8(+) T cell differentiation by a CD24-dependent mechanism.
Impact
Braciale et al., Charlottesville, United States. In Immunity, 2014
Mechanistically, CD24 was shown to regulate CD8(+) T cell activation through HMGB1-mediated engagement of T cell RAGE.
High-mobility group box 1 is dispensable for autophagy, mitochondrial quality control, and organ function in vivo.
Impact
Schwabe et al., New York City, United States. In Cell Metab, 2014
In vitro studies have demonstrated a critical role for high-mobility group box 1 (HMGB1) in autophagy and the autophagic clearance of dysfunctional mitochondria, resulting in severe mitochondrial fragmentation and profound disturbances of mitochondrial respiration in HMGB1-deficient cells.
High mobility group [corrected] box 1 mediates neutrophil recruitment in myocardial ischemia-reperfusion injury through toll like receptor 4-related pathway.
GeneRIF
Jiang et al., Yichang, China. In Gene, 2012
HMGB1 plays a central role in recruiting neutrophils during myocardial I/R leading to worsened myocardial I/R injury. This recruitment mechanism is possibly due to its inflammatory and chemokine functions based on the TLR4-dependent pathway.
High mobility group box 1 activates Toll like receptor 4 signaling in hepatic stellate cells.
GeneRIF
Guo et al., Shanghai, China. In Life Sci, 2012
HMGB1 activates TLR4 signaling in HSCs to enhance their inflammatory phenotype, indicating that TLR4 signaling need not rely solely on gut-derived LPS for activation during liver injury.
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.
Impact
GeneRIF
Jinushi et al., Sapporo, Japan. In Nat Immunol, 2012
TIM-3 circumvents the stimulatory effects of nucleic acids in tumor immunity by interactding with HMGB1 to interfere with the recruitment of nucleic acids into dendritic cell endosomes
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release.
GeneRIF
Bianchi et al., Milano, Italy. In J Exp Med, 2012
HMGB1 recruitment of leukocytes and their activation to secrete proinflammatory cytokines-depend on different and mutually exclusive redox states of the same polypeptide, which can be modified within the injured tissues after its release
Role of mouse spleen cell HMG proteins and their poly-ADP-ribosylation in betelnut induced carcinogenesis.
GeneRIF
Sharan et al., Shillong, India. In Indian J Biochem Biophys, 2002
under the influence of potential carcinogens AEBN or DEN, the mouse spleen cell HMG proteins create molecular conditions favourable to initiation of cancer
More papers using HMGB1 antibodies
BMP4-BMPR1A signaling in β cells is required for and augments glucose-stimulated insulin secretion
Supplier
Kovacs Peter et al., In Diabetes, 2006
... A.T., P.K., and A.K.), from the National Institutes of Health (U.S.) Grants R01 DK077097 and P30 DK040561 (to Y.H.T.), from the Tanita Healthy Weight Community (to Y.H.T.), and from the Deutsche Hochdruckliga (to W.K.).This work was supported by unrestricted grants from Merck Serono, Ipsen, and Novo ...
Induction of inflammatory and immune responses by HMGB1–nucleosome complexes: implications for the pathogenesis of SLE
Supplier
Voll Reinhard E. et al., In The Journal of Experimental Medicine, 2005
... Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice ...
Expression of Fas ligand in arteries of hypercholesterolemic rabbits accelerates atherosclerotic lesion formation.
Supplier
Rieux-Laucat Frederic, In PLoS ONE, 1999
... Antibodies used for flow cytometry, anti-TRAIL-R1 (wB-K32), anti-TRAIL-R2 (B-L27), anti-TRAIL-R3 (wB-B44), anti-TRAIL-R4 (wB-P30), and anti-TRAIL were from Diaclone (Besançon, France) ...
Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
Supplier
Noguchi Takayuki et al., In Critical Care, 1998
... Antibodies to rabbit polyclonal IgE anti-HMGB1 were purchased from Becton Dickinson and Company (Franklin Lakes, ...
Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation
Supplier
Bianchi Marco E. et al., In The Journal of Cell Biology, 1998
... Rabbit polyclonal anti-HMGB1 antibodies raised against peptide 166–181 were purchased from BD Biosciences, pAbs against box A were ...
Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes
Supplier
Habener Joel, In PLoS Medicine, 1997
... Rabbit anti-mouse HMGB1 antibody was obtained from BD Biosciences Pharmingen (San Diego, California, ...
The nucleotide sequence of cDNA coding for preproinsulin from the primate Macaca fascicularis
Supplier
Rodriguez-Zas Sandra L. et al., In Frontiers in Neuroinformatics, 1981
... The support of the National Institute on Drug Abuse Award P30 DA 018310 to the UIUC Neuroproteomics Center on Cell to Cell Signaling is gratefully acknowledged.
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