How Localized are Language Brain Areas? A Review of Brodmann Areas Involvement in Oral Language.
Miami, United States. In Arch Clin Neuropsychol, Feb 2016
Departing from seven meta-analytic studies of functional magnetic resonance imaging activity during the performance of different language activities, it is proposed here that there are two different language networks in the brain: first, a language reception/understanding system, including a "core Wernicke's area" involved in word recognition (BA21, BA22, BA41, and BA42), and a fringe or peripheral area ("extended Wernicke's area:" BA20, BA37, BA38, BA39, and BA40) involved in language associations (associating words with other information); second, a language production system ("Broca's complex:" BA44, BA45, and also BA46, BA47, partially BA6-mainly its mesial supplementary motor area-and extending toward the basal ganglia and the thalamus).
Lower [3H]LY341495 binding to mGlu2/3 receptors in the anterior cingulate of subjects with major depressive disorder but not bipolar disorder or schizophrenia.
Melbourne, Australia. In J Affect Disord, Feb 2016
Subsequently, density of [(3)H]LY341495 binding was measured in BA24(anterior cingulate cortex), BA17(visual cortex) and BA46(dorsolateral prefrontal cortex) from subjects with MDD, Bipolar Disorder(BPD), Schizophrenia(SCZ), and controls, as well as rats treated with imipramine (20mg/kg), fluoxetine (10mg/kg), or vehicle.
The rostral prefrontal cortex underlies individual differences in working memory capacity: An approach from the hierarchical model of the cognitive control.
Suita, Japan. In Cortex, Oct 2015
By manipulating an episodic factor of cognitive control (control in selecting an appropriate task set according to a temporal context) and using a parametric modulation analysis, we found that both high- and low- WMC individuals have similar activation patterns in the premotor cortex (BA6, 8), caudal prefrontal cortex (BA44, 45), and frontopolar cortex (BA10, 11), but differed in the rostral part of the prefrontal cortex (BA46/47); high WMC individuals showed greater activation in the higher episodic control condition, whereas low WMC individuals showed reduced activation when episodic control was required.
Monoclonal antibody therapy of ovarian cancer.
Wellesley, United States. In Expert Rev Anticancer Ther, 2005
The recent disappointing results with 90-yttrium-labeled anti-HMFG by single intraperitoneal administration have left the radiopharmaceutical field without a Phase III candidate.