Functional significance of the sex chromosomes during spermatogenesis.
Cincinnati, United States. In Reproduction, Jun 2015
The unique gene contents and genomic structures of the sex chromosomes reflect their strategies to express genes at various stages of spermatogenesis and reveal the driving forces that shape their evolution.Free Chinese abstract: A Chinese translation of this abstract is freely available at http://www.reproduction-online.org/content/149/6/R265/suppl/DC1.Free Japanese abstract: A Japanese translation of this abstract is freely available at http://www.reproduction-online.org/content/149/6/R265/suppl/DC2.
Network-assisted analysis of primary Sjögren's syndrome GWAS data in Han Chinese.
Beijing, China. In Sci Rep, 2014
Of these pSS candidates, 14 genes had been reported to be associated with any of pSS, RA, and SLE, including STAT4, GTF2I, HLA-DPB1, HLA-DRB1, PTTG1, HLA-DQB1, MBL2, TAP2, CFLAR, NFKBIE, HLA-DRA, APOM, HLA-DQA2 and NOTCH4.
HLA-DQ typing in the diagnostic algorithm of celiac disease.
Siena, Italy. In Rev Esp Enferm Dig, 2012
In patients with celiac disease (CD), 64% had DQ2 heterodimer (alpha5beta2), 13.5% DQ8 heterodimer without DQ2, 21.4% only beta2 chain and 1.1% DQ2 alpha5 chain. Presence of alpha5 chain did not predispose to CD. DQB1*02 allele was more frequent than in o