Etiology and Pathogenesis of Psoriatic Arthritis.
Rochester, United States. In Rheum Dis Clin North Am, Nov 2015
Although specific major histocompatibility complex class I molecules are associated with the psoriatic disease phenotype, no specific antigen or autoantibody has been identified.
The immunogenetics of Behçet's disease: A comprehensive review.
Bethesda, United States. In J Autoimmun, Nov 2015
In addition to the positive association of HLA-B*51, which was identified more than four decades ago, and which has since been confirmed in multiple populations, recent studies report additional independent associations in the major histocompatibility complex class I region.
The pharmacogenomics of epilepsy.
Pavia, Italy. In Expert Rev Neurother, Oct 2015
The indication for HLA-A*31:01 testing to identify individuals at risk for skin reactions from carbamazepine, or for CYP2C9 genotyping to identify individuals at risk for serious skin reactions from phenytoin is less compelling.
Class II HLA interactions modulate genetic risk for multiple sclerosis.
In Nat Genet, Oct 2015
Among new and previously identified class II risk alleles (HLA-DRB1*15:01, HLA-DRB1*13:03, HLA-DRB1*03:01, HLA-DRB1*08:01 and HLA-DQB1*03:02) and class I protective alleles (HLA-A*02:01, HLA-B*44:02, HLA-B*38:01 and HLA-B*55:01), we find evidence for two interactions involving pairs of class II alleles: HLA-DQA1*01:01-HLA-DRB1*15:01 and HLA-DQB1*03:01-HLA-DQB1*03:02.