Renz et al., Marburg an der Lahn, Germany. In Int Arch Allergy Immunol, Feb 2016
METHODS: For this purpose, we developed and evaluated a miniaturized chromatin immunoprecipitation (ChIP) assay allowing for a cost-effective assessment of histone acetylation of candidate genes in a quantitative fashion.
Artico et al., Padova, Italy. In Autoimmunity, Feb 2016
UNASSIGNED: Among epigenetic enzymes, histone deacetylases (HDACs) are responsible for regulating the expression of an extensive array of genes by reversible deacetylation of nuclear histones as well as a large number of non-histone proteins.
Histone maps and knockout assays are consistent with early transcriptional priming, while traditional transplantation experiments suggest that in vivo priming may still allow for plasticity given strong perturbations.
Fabianowska-Majewska et al., Łódź, Poland. In Int J Mol Sci, 2014
Epigenetic mechanisms in cancer cells comprise (i) post-translation histone modification (i.e., deacetylation and methylation); (ii) DNA global hypomethylation; (iii) promoter hypermethylation of tumour suppressor genes and genes important for cell cycle regulation, cell differentiation and apoptosis; and (iv) posttranscriptional regulation of gene expression by noncoding microRNA.
Jin et al., Changchun, China. In Int J Mol Sci, 2014
Changes in chromatin structure and heritably regulating the gene expression by epigenetic mechanisms, such as histone post-translational modification, are involved in most cellular biological processes.
Workman et al., Kansas City, United States. In Science, 2005
demonstrated that the dTip60 chromatin-remodeling complex acetylates nucleosomal phospho-H2Av and exchanges it with an unmodified H2Av; both the histone acetyltransferase dTip60 and the atpase Domino/p400 catalyze the exchange of phospho-H2Av
... murine anti-clathrin monoclonal antibody from Santa-Cruz Biotechnology (Santa-Cruz, CA, USA), rabbit anti-Histone H3 and rabbit anti-phospho-Histone H3 (Ser10) polyclonal antibodies from Cell Signaling (Danvers, MA, USA) and ...