Histone variants and cellular plasticity.
Laramie, United States. In Trends Genet, 30 Sep 2015
We highlight exciting new results suggesting that histone variants are essential players in the control of cellular plasticity during development and in the adult nervous system.
Hijacked in cancer: the KMT2 (MLL) family of methyltransferases.
United States. In Nat Rev Cancer, Jun 2015
Histone-lysine N-methyltransferase 2 (KMT2) family proteins methylate lysine 4 on the histone H3 tail at important regulatory regions in the genome and thereby impart crucial functions through modulating chromatin structures and DNA accessibility.
Comprehensive Catalog of Currently Documented Histone Modifications.
Philadelphia, United States. In Cold Spring Harb Perspect Biol, Dec 2014
SUMMARYModern techniques in molecular biology, genomics, and mass spectrometry-based proteomics have identified a large number of novel histone posttranslational modifications (PTMs), many of whose functions are still under intense investigation.
The role of epigenetics in spermatogenesis.
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Samsun, Turkey. In Turk J Urol, 2013
Epigenetic modifications, including DNA methylation, histone modifications, and chromatin remodeling are substantial regulators of spermatogenesis.