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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 May 2015.

Histone H2A variant

Histone
Top mentioned proteins: HDAC, CAN, ACID, V1a, H4
Papers using Histone antibodies
Male gametogenesis without centrioles
Supplier
Glover David M. et al., In Open Biology, 2010
... ]; mouse anti-γ-tubulin (GTU88, Sigma); mouse anti-α-tubulin (DM1a, Sigma); rabbit anti-phospho-Histone H3 Ser10 (Millipore); mouse anti-phospho-Histone H3 Ser10 (Cell Signaling).
Intracellular Ca2+ regulating proteins in vascular smooth muscle cells are altered with type 1 diabetes due to the direct effects of hyperglycemia
Supplier
Cheng Juei-Tang et al., In Cardiovascular Diabetology, 2009
... Antibodies to GATA-4, Histone H3 and goat anti-rabbit IgG-HRP-linked were obtained from Santa Cruz biotechnology, Inc ...
18F-FDG small-animal PET/CT differentiates trastuzumab-responsive from unresponsive human breast cancer xenografts in athymic mice
Supplier
Skala Melissa C. et al., In Biomedical Optics Express, 2008
... Mitotic cells were first marked using a Phospho-Histone H3 (Ser10) antibody (Cell Signaling Technology, Danvers, MA) ...
A novel role for proteomics in the discovery of cell-surface markers on stem cells: scratching the surface
Supplier
Zhou Rong et al., In Stem Cells International, 2007
... (ab7961), and phospho-Ser10-Histone H3 (ab5176) (Abcam, Cambridge, MA) ...
Discriminating roles of desmosomal cadherins: beyond desmosomal adhesion.
Supplier
Hotchin Neil, In PLoS ONE, 2006
... (Ab 703), anti-pan desmoglein, anti-desmoplakin, anti phospho-S10-Histone H3 (Ab5176) polyclonal antibodies and rat anti-BrdU monoclonal antibody were purchased from Abcam (Cambridge, UK) ...
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Papers on Histone
The Histone Methyltransferase Inhibitor BIX01294 Inhibits HIF-1α Stability and Angiogenesis.
New
Lee et al., Taegu, South Korea. In Mol Cells, 27 Jun 2015
Recent studies have shown that, BIX01294, a G9a histone methyltransferase (HMT)- specific inhibitor, induces apoptosis and inhibits the proliferation, migration, and invasion of cancer cells.
A miniaturized readout strategy for endogenous histone deacetylase activity.
New
Schwarzer et al., Tübingen, Germany. In Mol Biosyst, 26 Jun 2015
UNASSIGNED: Histone deacetylases are important drug targets, which are difficult to characterize due to their poor accessibility.
Global quantification of heterochromatin-associated histone methylations in cell lines with differential sensitivity to ionizing radiation.
New
Gezer et al., İstanbul, Turkey. In Acta Biochim Pol, 26 Jun 2015
UNASSIGNED: Histone modifications are involved in the DNA damage response (DDR).
EnD-Seq and AppEnD: sequencing 3' ends to identify nontemplated tails and degradation intermediates.
New
Marzluff et al., Chapel Hill, United States. In Rna, 26 Jun 2015
Applying EnD-Seq and AppEnD to histone mRNAs revealed that a significant fraction of cytoplasmic histone mRNAs end in one or two uridines, which have replaced the 1-2 nt at the 3' end of mature histone mRNA maintaining the length of the histone transcripts.
HDAC8: a multifaceted target for therapeutic interventions.
Review
New
Jung et al., Freiburg, Germany. In Trends Pharmacol Sci, 23 Jun 2015
UNASSIGNED: Histone deacetylase 8 (HDAC8) is a class I histone deacetylase implicated as a therapeutic target in various diseases, including cancer, X-linked intellectual disability, and parasitic infections.
Hijacked in cancer: the KMT2 (MLL) family of methyltransferases.
New
Impact
Dou et al., United States. In Nat Rev Cancer, 22 Jun 2015
Histone-lysine N-methyltransferase 2 (KMT2) family proteins methylate lysine 4 on the histone H3 tail at important regulatory regions in the genome and thereby impart crucial functions through modulating chromatin structures and DNA accessibility.
Calibrating ChIP-Seq with Nucleosomal Internal Standards to Measure Histone Modification Density Genome Wide.
New
Ruthenburg et al., Chicago, United States. In Mol Cell, 20 Jun 2015
To address these problems, we developed Internal Standard Calibrated ChIP (ICeChIP), wherein a native chromatin sample is spiked with nucleosomes reconstituted from recombinant and semisynthetic histones on barcoded DNA prior to immunoprecipitation. ICeChIP measures local histone modification densities on a biologically meaningful scale, enabling unbiased trans-experimental comparisons, and reveals unique insight into the nature of bivalent domains.
Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure.
Review
New
Condorelli et al., Milano, Italy. In Nat Rev Cardiol, 12 Jun 2015
The most studied of the histone changes are acetylation and methylation.
Genesis of Chromatin and Transcription Dynamics in the Origin of Species.
Review
New
Impact
Timmers et al., Utrecht, Netherlands. In Cell, 07 Jun 2015
UNASSIGNED: Histone proteins compact and stabilize the genomes of Eukarya and Archaea.
Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells.
New
Impact
Banaszynski et al., Cambridge, United Kingdom. In Nature, 04 Jun 2015
Recent studies have demonstrated that a subset of transposable elements, endogenous retroviral elements (ERVs) containing long terminal repeats (LTRs), are silenced through trimethylation of histone H3 on lysine 9 (H3K9me3) by ESET (also known as SETDB1 or KMT1E) and a co-repressor complex containing KRAB-associated protein 1 (KAP1; also known as TRIM28) in mouse embryonic stem cells.
Epigenetics. Restricted epigenetic inheritance of H3K9 methylation.
New
Impact
Allshire et al., Edinburgh, United Kingdom. In Science, 03 May 2015
Posttranslational histone modifications are believed to allow the epigenetic transmission of distinct chromatin states, independently of associated DNA sequences.
Application of the Protein Semisynthesis Strategy to the Generation of Modified Chromatin.
New
Impact
Muir et al., Princeton, United States. In Annu Rev Biochem, 12 Apr 2015
UNASSIGNED: Histone proteins are subject to a host of posttranslational modifications (PTMs) that modulate chromatin structure and function.
Treatment of chronic kidney diseases with histone deacetylase inhibitors.
Review
New
Zhuang et al., Shanghai, China. In Front Physiol, Dec 2014
Histone deacetylases (HDACs) induce deacetylation of both histone and non-histone proteins and play a critical role in the modulation of physiological and pathological gene expression.
Initiation of Meiotic Homologous Recombination: Flexibility, Impact of Histone Modifications, and Chromatin Remodeling.
Review
New
Nicolas et al., Debrecen, Hungary. In Cold Spring Harb Perspect Biol, Dec 2014
Predisposed chromatin accessibility, but also a range of transcription factors, chromatin remodelers, and histone modifiers likely promote local recruitment of DSB proteins, as well as mobilization, sliding, and eviction of nucleosomes before and after the occurrence of meiotic DSBs.
Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.
New
Knipe et al., Boston, United States. In Mbio, Dec 2014
Instead, we found that the levels of a histone-modifying enzyme, SETD1A methyltransferase, and histone H3 lysine 4 trimethylation were reduced on IE and early (E) gene promoters in BAF-depleted cells during HSV lytic infection.
Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin.
GeneRIF
Tulin et al., Philadelphia, United States. In Proc Natl Acad Sci U S A, 2011
PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).
Loss of the histone variant H2A.Z restores capping to checkpoint-defective telomeres in Drosophila.
GeneRIF
Rong, Bethesda, United States. In Genetics, 2008
in the absence of H2A.Z, checkpoint-defective telomeres adopt alternative structures, which are permissive for the loading of the capping machinery at Drosophila telomeres.
Activation of facultatively silenced Drosophila loci associates with increased acetylation of histone H2AvD.
GeneRIF
Kato et al., Tokyo, Japan. In Genes Cells, 2008
N-terminal region of H2AvD plays a pivotal role in transcriptional activation and that induction of transiently silenced Drosophila loci associates with increased acetylation of H2AvD.
RSF governs silent chromatin formation via histone H2Av replacement.
GeneRIF
Hirose et al., Shizuoka, Japan. In Plos Genet, 2008
In Rsf-1 mutant, the levels of histone H3K9 dimethylation and histone H2A variant H2Av were significantly reduced in an euchromatic region juxtaposed with heterochromatin.
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions.
Impact
GeneRIF
Workman et al., Kansas City, United States. In Science, 2005
demonstrated that the dTip60 chromatin-remodeling complex acetylates nucleosomal phospho-H2Av and exchanges it with an unmodified H2Av; both the histone acetyltransferase dTip60 and the atpase Domino/p400 catalyze the exchange of phospho-H2Av
More papers using Histone antibodies
Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa
Supplier
Liu Zhi-Ren et al., In Cell research, 2005
... Antibodies against HA and His tags, GAPDH, Lamin A/C, β-actin, and Histone 2A were purchased from Roche, Cell signaling, Upstate, and Chemicon respectively ...
Evidence supporting the hypothesis that one of the main functions of the aryl hydrocarbon receptor is mediation of cell stress responses.
Supplier
Uversky Vladimir N., In PLoS ONE, 2005
... Anti-Histone H3 antibody was purchased from Abcam Inc. ...
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
Supplier
Ouellette Michel M., In PLoS ONE, 2003
... Antibodies recognizing the cleaved caspase-3, phospho-Chk1 (Ser317), phospho-Chk2 (Thr68), and phospho-Histone H3 (Ser10) were purchased from Cell Signaling Technology (Danvers, MA) ...
Ductal carcinoma in situ: USC/Van Nuys Prognostic Index and the impact of margin status.
Supplier
Aziz Syed A., In PLoS ONE, 2002
... Anti-ATOX1 mouse monoclonal antibodies, anti-VCP and anti-Histone H2B antibodies were from Abcam (Cambridge, UK) ...
Regulation of eNOS Expression in Brain Endothelial Cells by Perinuclear EP3 Receptors.
Supplier
Koch Karl-Wilhelm, In PLoS ONE, 2001
... murine anti-clathrin monoclonal antibody from Santa-Cruz Biotechnology (Santa-Cruz, CA, USA), rabbit anti-Histone H3 and rabbit anti-phospho-Histone H3 (Ser10) polyclonal antibodies from Cell Signaling (Danvers, MA, USA) and ...
A review of techniques and results obtained in one laboratory by an integrated system of methods designed for routine clinical flow cytometric DNA analysis
Supplier
McHugh Peter J et al., In Molecular Therapy. Nucleic Acids, 1989
... The sample was stained with 2 µl of Alexa fluor 647-conjugated anti-Histone H3 pSer10 antibody (Cell Signaling 9716; Cell Signaling Technology, ...
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