Are epigenetic drugs for diabetes and obesity at our door step?
Kingsville, United States. In Drug Discov Today, Jan 2016
These classes include histone deacetylase inhibitors (HDACi), histone acetyltransferase inhibitors (HATi), protein arginine methyltransferase inhibitors (PRMTis), DNA methyltransferase inhibitors (DNMTis), histone demethylating inhibitors (HDMis), and sirtuin-activating compounds (STACs).
Histone modification and chromatin remodeling during NER.
Cardiff, United Kingdom. In Dna Repair (amst), Dec 2015
We focused on how GG-NER relates to histone acetylation for its functioning and we identified the histone acetyltransferase Gcn5 and acetylation at lysines 9/14 of histone H3 as a major factor in enabling efficient repair.