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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Histamine N-methyltransferase

Histamine N-Methyltransferase, HMT, HNMT, H2-M3
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers using Histamine N-Methyltransferase antibodies
Gitools: analysis and visualisation of genomic data using interactive heat-maps.
Blagosklonny Mikhail V., In PLoS ONE, 2010
... Pearson's correlation coefficient (PCC) of HDM and HMT expression profiles in normal tissues and cancer cell lines was analyzed using Gitools.We used the TissueScan Cancer Survey Tissue qPCR panel 384-1 (OriGene, Cat# CSRT102), which contains ...
A conducting salt-based amperometric biosensor for measurement of extracellular lactate accumulation in ischemic myocardium
Willander Magnus et al., In Sensors (Basel, Switzerland), 1996
... O], hexamethylenetetramine (HMT), d-glucose, l-glucose-fructose were purchased from Sigma Aldrich (Sweden) ...
Papers on Histamine N-Methyltransferase
Histamine N-methyltransferase Thr105Ile polymorphism is associated with Parkinson's disease.
Krainc et al., Split, Croatia. In Neurobiol Aging, 2012
The results of this study indicated that Histamine N-methyltransferase Thr105Ile polymorphism is associated Parkinson's disease.
No association between histamine N-methyltransferase functional polymorphism Thr105Ile and Alzheimer's disease.
Terzić et al., Split, Croatia. In Neurosci Lett, 2011
Lack of the association of HNMT Thr105Ile functional polymorphism with Alzheimer's disease is found.
Nonconventional CD8+ T cell responses to Listeria infection in mice lacking MHC class Ia and H2-M3.
Wang et al., Chicago, United States. In J Immunol, 2011
Similar to H2-M3-restricted CD8-positive T cells, CD8+ T cells restricted to other major histocompatibility class Ib molecules are able to undergo extensive proliferation after primary infection with Listeria monocytogenes.
Histamine-N-methyl transferase polymorphism and risk for multiple sclerosis.
Jiménez-Jiménez et al., Badajoz, Spain. In Eur J Neurol, 2010
our results suggest that, despite the possible role of histamine in the inflammatory processes related with the pathogenesis of MS, HNMT polymorphism is not related with the risk for MS in Caucasian Spanish people
Histamine N-methyltransferase Thr105Ile is not associated with Parkinson's disease or essential tremor.
Farrer et al., Jacksonville, United States. In Parkinsonism Relat Disord, 2010
This study do not support the HNMT Thr105Ile variant as a factor in disease development or a genetic link between the disorders.
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