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Keratin 33B

hHa3-II, Ha3-II
The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: cytokeratin, HAIR, HA-8, K37, hHa3-I
Papers on hHa3-II
Expression of type I hair keratins in follicular tumours.
Grosshans et al., Strasbourg, France. In Br J Dermatol, 2001
METHODS: We performed immunohistochemistry on paraffin sections of formalin-fixed pilomatrixomas (40), trichoepitheliomas (10), trichoblastomas (10), desmoplastic trichoepitheliomas (10) and basal cell carcinomas (10), using antibodies against type I hair keratins hHa1, hHa2, hHa3-II, hHa4, hHa5, hHa6, hHa7 and hHa8 as well as cytokeratin CK17.
Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype.
Boehm et al., Freiburg, Germany. In Dev Dyn, 2000
Expression of Whn in HeLa cells induced expression of human hair keratin genes Ha3-II and Hb5.
The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.
Schweizer et al., Heidelberg, Germany. In J Biol Chem, 1999
Group A (hHa1, hHa3-I, hHa3-II, hHa4) and B (hHa7, hHa8) each contains structurally related hair keratins, whereas group C members hHa2, hHa5, and hHa6 represent structurally rather unrelated hair keratins.
Characterization of a 190-kilobase pair domain of human type I hair keratin genes.
Schweizer et al., Heidelberg, Germany. In J Biol Chem, 1998
Polymerase chain reaction-based screening of an arrayed human P1 artificial chromosome (PAC) library using primer pairs specific for the human type I hair keratins hHa3-II or hHa6, led to the isolation of two PAC clones, which covered 190 kilobase pairs (kbp) of genomic DNA and contained nine human type I hair keratin genes, one transcribed hair keratin pseudogene, as well as one orphan exon.
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