Getting to the heart of hERG K(+) channel gating.
Australia. In J Physiol, Jul 2015
Potassium ion channels encoded by the human ether-a-go-go related gene (hERG) form the ion-conducting subunit of the rapid delayed rectifier potassium current (IKr ).
The structural mechanism of KCNH-channel regulation by the eag domain.
Seattle, United States. In Nature, 2013
The KCNH voltage-dependent potassium channels (ether-à-go-go, EAG; EAG-related gene, ERG; EAG-like channels, ELK) are important regulators of cellular excitability and have key roles in diseases such as cardiac long QT syndrome type 2 (LQT2), epilepsy, schizophrenia and cancer.