Hepcidin and the iron enigma in HCV infection.
Athens, Greece. In Virulence, 13 Apr 2014
Hepcidin is a 25-aa peptide, present in human serum and urine and represents the key peptide hormone, which modulates iron homeostasis in the body.
Systemic iron homeostasis.
In Physiol Rev, Oct 2013
The iron hormone hepcidin and its receptor and cellular iron exporter ferroportin control the major fluxes of iron into blood plasma: intestinal iron absorption, the delivery of recycled iron from macrophages, and the release of stored iron from hepatocytes.
Hepcidin and HFE protein: Iron metabolism as a target for the anemia of chronic kidney disease.
Milano, Italy. In World J Nephrol, 2013
UNLABELLED: The anemia of chronic kidney disease and hemodialysis is characterized by chronic inflammation and release of cytokines, resulting in the upregulation of the iron hormone hepcidin, also increased by iron therapy and reduced glomerular filtration, with consequent reduction in iron absorption, recycling, and availability to the erythron.