Biology of hyaluronan: Insights from genetic disorders of hyaluronan metabolism.
Winnipeg, Canada. In World J Biol Chem, Sep 2015
Its levels are determined, in part, by the hyaluronan synthases, HAS1, HAS2, and HAS3, and three hyaluronidases, HYAL1, HYAL2 and HYAL3.
Regulated Hyaluronan Synthesis by Vascular Cells.
Varese, Italy. In Int J Cell Biol, 2014
HA synthesis is regulated by several factors, including the phosphorylation of HA synthase 2 (HAS2) and other covalent modifications including ubiquitination and O-GlcNAcylation.