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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Activating transcription factor 7 interacting protein

hAM, MCAF1, MBD1-containing chromatin-associated factor 1, MBD1-containing chromatin-associated factor
ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010] (from NCBI)
Top mentioned proteins: adrenomedullin, V1a, Calcitonin, ACID, CAN
Papers on hAM
Selective cytotoxicity and cell death induced by human amniotic membrane in hepatocellular carcinoma.
Botelho et al., Coimbra, Portugal. In Med Oncol, Dec 2015
Our team already proved that human amniotic membrane (hAM) is able to inhibit the metabolic activity of several human cancer cell lines, including HCC cell lines.
Retention of Endogenous Viable Cells Enhances the Anti-Inflammatory Activity of Cryopreserved Amnion.
Danilkovitch et al., Portage, United States. In Adv Wound Care (new Rochelle), Oct 2015
UNASSIGNED: Objective: Human amniotic membrane (hAM) has been used to treat wounds for more than 100 years.
Angiogenic Potential of Cryopreserved Amniotic Membrane Is Enhanced Through Retention of All Tissue Components in Their Native State.
Danilkovitch et al., United States. In Adv Wound Care (new Rochelle), Oct 2015
Both fresh human amniotic membrane (hAM) containing viable cells and devitalized hAM have been shown to stimulate angiogenesis in chronic wounds.
RanBPM regulates Zta-mediated transcriptional activity in Epstein-Barr virus.
Chang et al., Taipei, Taiwan. In J Gen Virol, Aug 2015
Epstein-Barr virus (EBV) expresses two immediate-early proteins, Rta and Zta, which are key transcription factors that can form a complex with MCAF1 at Zta-responsive elements (ZREs) to synergistically activate several viral lytic genes.
The Immunosuppressive Activity of Amniotic Membrane Mesenchymal Stem Cells on T Lymphocytes.
Jalili et al., Tehrān, Iran. In Avicenna J Med Biotechnol, Jul 2015
There is only limited knowledge on the immunomodulatory properties of human Amniotic Membrane-derived Mesenchymal Stem Cells (hAM-MSCs).
Biocompatibility of quantum dots (CdSe/ZnS ) in human amniotic membrane-derived mesenchymal stem cells in vitro.
Feng et al., China. In Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub, Jun 2015
BACKGROUND AND AIM: Amniotic membrane-derived mesenchymal stem cells (hAM-dMSCs) are a potential source of mesenchymal stem cells which could be used to repair skin damage.
An epigenetic regulator: methyl-CpG-binding domain protein 1 (MBD1).
Chan et al., Hong Kong, Hong Kong. In Int J Mol Sci, 2014
MBD1 acts as an epigenetic regulator via different mechanisms, such as the formation of the MCAF1/MBD1/SETDB1 complex or the MBD1-HDAC3 complex.
Intact human amniotic membrane differentiated towards the chondrogenic lineage.
Wolbank et al., Vienna, Austria. In Cell Tissue Bank, 2014
Human amniotic membrane (hAM) represents a tissue that is well established as biomaterial in the clinics with potential for new applications in regenerative medicine.
Storage and qualification of viable intact human amniotic graft and technology transfer to a tissue bank.
Gindraux et al., Besançon, France. In Cell Tissue Bank, 2014
Human amniotic membrane (hAM) is known to have good potential to help the regeneration of tissue.
Comparing supportive properties of poly lactic-co-glycolic acid (PLGA), PLGA/collagen and human amniotic membrane for human urothelial and smooth muscle cells engineering.
Saeed et al., Tehrān, Iran. In Urol J, 2014
PURPOSE: To compare human urothelial and smooth muscle cells attachment and proliferation using three different matrices; poly lactic-co-glycolic acid (PLGA), PLGA/collagen and human amniotic membrane (hAM).
Effect of amniotic membrane proteins in human cancer cell lines: an exploratory study.
Botelho et al., Coimbra, Portugal. In J Membr Biol, 2014
Human amniotic membrane (hAM) has recently drawn attention as an upcoming anti-cancer therapy.
MCAF1 and Rta-activated BZLF1 transcription in Epstein-Barr virus.
Chang et al., Taipei, Taiwan. In Plos One, 2013
In a DNA affinity precipitation assay, ATF2 was found to associate with an Rta-interacting protein, MCAF1, at the ZII element.
Growth factors and their receptors derived from human amniotic cells in vitro.
Kawiak et al., Warsaw, Poland. In Folia Histochem Cytobiol, 2013
Human amnions (hAM) were isolated, and amnion circles were dissected for in vitro analysis.
Transcriptional repressor domain of MBD1 is intrinsically disordered and interacts with its binding partners in a selective manner.
Swaminathan et al., Singapore, Singapore. In Sci Rep, 2013
One of its regulators is the 64-residue C-terminal Transcriptional Repressor Domain (the TRD) of MBD1, which recruits several repressor proteins such as MCAF1, HDAC3 and MPG that are essential for the gene silencing.
The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation.
Plath et al., Los Angeles, United States. In Epigenetics Chromatin, 2013
Here, we studied ATF7IP (MCAF1), a protein previously characterized to coordinate DNA methylation and histone H3K9 methylation through interactions with the methyl-DNA binding protein MBD1 and the histone H3K9 methyltransferase SETDB1, as a candidate maintenance factor of the Xi.
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.
UK Testicular Cancer Collaboration et al., United Kingdom. In Nat Genet, 2010
Studies identified three new susceptibility loci DMRT1, TERT and ATF7IP associated with testicular germ cell cancer.
MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity.
Nakao et al., Kumamoto, Japan. In J Biol Chem, 2009
Two evolutionarily conserved domains of MCAF1 directly interact with Sp1 and the general transcriptional apparatus. Selective depletion of MCAF1 or Sp1 down-regulates TERT and TERC genes in cultured cells, which results in decreased telomerase activity.
Structure of the small ubiquitin-like modifier (SUMO)-interacting motif of MBD1-containing chromatin-associated factor 1 bound to SUMO-3.
Shirakawa et al., Kyoto, Japan. In J Biol Chem, 2009
the acidic stretch of the SIM of MCAF1 plays an important role in the binding to SUMO-3.
Involvement of SUMO modification in MBD1- and MCAF1-mediated heterochromatin formation.
Saitoh et al., Kumamoto, Japan. In J Biol Chem, 2006
MBD1- and MCAF1-mediated heterochromatin formation involves SUMO modification
Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins.
Nakao et al., Kumamoto, Japan. In J Biol Chem, 2005
These data suggest that MBD1.MCAF1.SETDB1 complex facilitates the formation of heterochromatic domains, emphasizing the role of MCAF/AM family proteins in epigenetic control, and describe a new family member, MCAF2.
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