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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Ring finger protein, LIM domain interacting

HAIR, RLIM, Rnf12
may play a role in the regulation of genes in specific neuronal subtypes [RGD, Feb 2006] (from NCBI)
Papers on HAIR
RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation.
Impact
GeneRIF
Gribnau et al., Rotterdam, Netherlands. In Nature, 2012
RNF12 causes REX1 breakdown through dose-dependent catalysis, thereby representing an important pathway to initiate X-chromosome inactivation
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells.
Impact
GeneRIF
Bach et al., Worcester, United States. In Cell, 2012
Results provide strong evidence that RLIM/Rnf12 is required for the survival of differentiated milk-producing alveolar cells in pregnant and lactating female mice.
RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration.
GeneRIF
Yu et al., Shanghai, China. In Biochem Biophys Res Commun, 2011
these results indicated that RLIM is an important positive regulator in TGF-beta signaling pathway and cell migration.
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.
GeneRIF
Chambers et al., Edinburgh, United Kingdom. In Hum Genet, 2011
The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells.
RNF12 activates Xist and is essential for X chromosome inactivation.
GeneRIF
Gribnau et al., Rotterdam, Netherlands. In Plos Genet, 2010
RNF12 is essential for initiation of XCI and is mainly involved in the regulation of Xist.
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