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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 31 Mar 2015.

Myosin IG

HA2, K32
MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010] (from NCBI)
Top mentioned proteins: AE1, ACID, CAN, HAD, Tec
Papers on HA2
A Switch from Parallel to Antiparallel Strand Orientation in a Coiled-Coil X-Ray Structure via Two Core Hydrophobic Mutations.
New
Lai et al., Ben Mehidi, Algeria. In Biopolymers, 06 Apr 2015
Here we report the X-ray structure of a model coiled-coil peptide, HA2-Del-L2seM, which forms an unanticipated core antiparallel dimer with potential sites for discrete higher-order multimerization (trimer or tetramer).
Dynamic Changes during Acid-Induced Activation of Influenza Hemagglutinin.
New
Lee et al., Seattle, United States. In Structure, 02 Apr 2015
While high-resolution structures are available for the pre-fusion HA ectodomain and the post-fusion HA2 subunit, the sequence of conformational changes during HA activation has eluded structural characterization.
Validation of the Italian translation of the Revised Temperament and Character Inventory - TCI-140 - in adult participants and in participants with medical diseases.
New
Cloninger et al., Ancona, Italy. In Compr Psychiatry, Jan 2015
Subscales of: PS4, PS3 PS2, PS1, NS3 for factor 1; HA2, HA1, HA4, HA3 for factor 2; RD1, RD2 and RD3 for factor 3; NS4, NS1 and NS2 for factor 4. Three factors that were identified accounted for 58.3% of the variance for character subscales of: SD3, SD5, SD1, SD2 for factor 1; C4, C1, C5, SD4, C3 for factor 2; ST2, ST1, ST3, C2 for factor 3. CONCLUSION: The reliability coefficients were significantly good for some dimensions of TCI-140 and showed a good correlation after time, while some dimensions as NS have low reliability.
Volume Regulation and Renal Function at High Altitude across Gender.
New
Goswami et al., Graz, Austria. In Plos One, Dec 2014
ages: 19 - 65 yrs), who ascended to a height of 3440m (HA1), on the 3rd day and to 5050m (HA2), on the 14th day.
Construction and heterologous expression of a truncated Haemagglutinin (HA) protein from the avian influenza virus H5N1 in Escherichia coli.
New
Shaharum et al., Malaysia. In Trop Biomed, Dec 2014
Here, a recombinant gene encoding of peptide epitopes, consisting fragments of HA1, HA2 and a polybasic cleavage site of H5N1 strain Malaysia, was amplified and cloned into pET-47b(+) bacterial expression vector.
[Advances in research and development of universal influenza vaccines].
Review
He et al., In Bing Du Xue Bao, 2014
This review describes the research progress in conserved epitopes of influenza virus, the advances in the research and development of universal influenza vaccines based on the relatively conserved sequences of NP, M2e, HA2, and headless HA, the mechanisms of cross-protection, and the methods to improve cross-protection.
New vaccines against influenza virus.
Review
Kang et al., Atlanta, United States. In Clin Exp Vaccine Res, 2014
The strategies of universal vaccines include the matrix 2 protein, the hemagglutinin HA2 stalk domain, and T cell-based multivalent antigens.
Influenza virus hemagglutinin as a vaccine antigen produced in bacteria.
Review
Sączyńska, Warsaw, Poland. In Acta Biochim Pol, 2013
The vast majority of bacterial HAs have been based on the HA1 subunit of HA expressed separately or as a component of conjugate vaccines, but those based on the ectodomain and the HA2 subunit have also been reported.
Protective immunity based on the conserved hemagglutinin stalk domain and its prospects for universal influenza vaccine development.
Review
Rajput et al., Delhi, India. In Biomed Res Int, 2013
Its HA2 subunit (stem domain) is most conserved as compared to HA1 subunit (globular head domain).
Structural biology of the influenza virus fusion peptide.
Review
Worch, Warsaw, Poland. In Acta Biochim Pol, 2013
The fusion is mediated by the influenza hemagglutinin protein (HA), in particular by the fusion peptide (HAfp) located in the N-terminal fragment of HA2 subunit.
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.
Impact
Liu et al., Houston, United States. In Immunity, 2011
Although DDX1 bound poly I:C via its Helicase A domain, DHX36 and DDX21 bound the TIR domain of TRIF via their HA2-DUF and PRK domains, respectively.
Minor histocompatibility antigen HA-1 and HA-2 polymorphisms in Taiwan: frequency and application in hematopoietic stem cell transplantation.
GeneRIF
Yang et al., Taipei, Taiwan. In Clin Chem Lab Med, 2010
the information on allele and genotype frequencies of HA-1 and HA-2 in a Taiwanese population
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).
GeneRIF
Shaw et al., Bethesda, United States. In J Biol Chem, 2010
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain
Mismatch for the minor histocompatibility antigen HA-2 and GVHD occurrence in HLA-A*0201-positive Tunisian recipients of HSCs.
GeneRIF
Hmida et al., Tunisia. In Immunol Invest, 2009
gene polymorphism does not have any significant effect on the occurrence of GVHD in Tunisia
Antibody recognition of a highly conserved influenza virus epitope.
Impact
Wilson et al., Los Angeles, United States. In Science, 2009
In contrast to other structurally characterized influenza antibodies, CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1 and HA2.
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.
Impact
Dowdy et al., San Diego, United States. In Nat Med, 2004
Using this information, we developed a transducible, pH-sensitive, fusogenic dTAT-HA2 peptide that markedly enhanced TAT-Cre escape from macropinosomes.
In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens.
Impact
Goulmy et al., Newcastle upon Tyne, United Kingdom. In Nat Med, 2002
Therefore, using a skin-explant assay we investigated the in situ activities of cytotoxic T lymphocytes (CTLs) specific for the ubiquitously expressed mHag H-Y and for the hematopoietic-restricted mHags HA-1 and HA-2.
Atomic structure of the ectodomain from HIV-1 gp41.
Impact
Wiley et al., Boston, United States. In Nature, 1997
These features, and the existence of a similar reversal of chain direction in the fusion pH-induced conformation of influenza virus HA2 and in the transmembrane subunit of Moloney murine leukaemia virus (Fig. 1a-d), suggest a common mechanism for initiating fusion.
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