GoPubMed Proteins lists recent and important papers and reviews for
proteins. Page last changed on 14 Mar 2013.
Myosin IG
HA2, K32
MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010] (from
NCBI)
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Papers on
HA2
Patient mobility for cardiac problems: a risk-adjusted analysis in Italy.
New
In Bmc Health Serv Res, 12 Mar 2013
The three HAs (HA1, HA2, HA3) recorded 25,017 planned hospitalizations in cardiac surgery units in the period 2001--2007.
A novel DNA vaccine expressing the Ag85A-HA2 fusion protein provides protection against influenza A virus and Staphylococcus aureus.
New
In Virol J, 03 Mar 2013
The aim of the research was designed a novel DNA vaccine encoding the Mycobacterium tuberculosis secreted antigen Ag85A fused with the influenza A virus (IAV) HA2 protein to provide protection against both influenza and secondary infection with S. aureus.
Detection of closed influenza virus hemagglutinin fusion peptide structures in membranes by backbone (13)CO- (15)N rotational-echo double-resonance solid-state NMR.
New
East Lansing, United States. In J Biomol Nmr, 28 Feb 2013
The influenza virus fusion peptide is the N-terminal ~20 residues of the HA2 subunit of the hemagglutinin protein and this peptide plays a key role in the fusion of the viral and endosomal membranes during initial infection of a cell.
Biological properties of h5 hemagglutinin expressed by vaccinia virus vector and its immunological reactivity with human sera.
New
Bangkok, Thailand. In Viral Immunol, 28 Feb 2013
Western blot analysis demonstrated that the rVac-H5 HA protein was post-translationally processed by proteolytic cleavage of the HA0 precursor into HA1 and HA2 domains; and all of these HA forms were immunogenic in BALB/c mice.
Hemagglutinin homologue from H17N10 bat influenza virus exhibits divergent receptor-binding and pH-dependent fusion activities.
New
Los Angeles, United States. In Proc Natl Acad Sci U S A, 22 Feb 2013
Furthermore, the fusion mechanism is also distinct; trypsin digestion with recombinant H17 protein, when exposed to pH 4.0, did not degrade the HA1 and HA2, in contrast to other HAs.
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.
Impact
Houston, United States. In Immunity, 2011
Although DDX1 bound poly I:C via its Helicase A domain, DHX36 and DDX21 bound the TIR domain of TRIF via their HA2-DUF and PRK domains, respectively.
Minor histocompatibility antigen HA-1 and HA-2 polymorphisms in Taiwan: frequency and application in hematopoietic stem cell transplantation.
GeneRIF
Taipei, Taiwan. In Clin Chem Lab Med, 2010
the information on allele and genotype frequencies of HA-1 and HA-2 in a Taiwanese population
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).
GeneRIF
Bethesda, United States. In J Biol Chem, 2010
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain
Mismatch for the minor histocompatibility antigen HA-2 and GVHD occurrence in HLA-A*0201-positive Tunisian recipients of HSCs.
GeneRIF
Tunis, Tunisia. In Immunol Invest, 2009
gene polymorphism does not have any significant effect on the occurrence of GVHD in Tunisia
Recent advances in protein transduction technology.
Review
Fort Worth, United States. In Cell Transplant, 2009
Moreover, the use of the NH2-terminal domain of the influenza virus hemagglutinin-2 subunit (HA2) or photosensitive PTDs has been shown to specifically enhance macropinosome escape.
Conserved epitopes of influenza A virus inducing protective immunity and their prospects for universal vaccine development.
Review
Bratislava, Slovakia. In Virol J, 2009
Antigenically conserved fusion-active subunit of hemagglutinin (HA2 gp) and ectodomain of matrix protein 2 (eM2) are promising candidates for preparation of broadly protective HA2- or eM2-based vaccine that may aid in pandemic preparedness.
Antibody recognition of a highly conserved influenza virus epitope.
Impact
Los Angeles, United States. In Science, 2009
In contrast to other structurally characterized influenza antibodies, CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1 and HA2.
Composition and functions of the influenza fusion peptide.
Review
Atlanta, United States. In Protein Pept Lett, 2008
The most conserved region of HA is at the N-terminus of the HA2 subunit, a relatively hydrophobic sequence of amino acids referred to as the fusion peptide.
Characterizing and optimizing immune responses to leukaemia antigens after allogeneic stem cell transplantation.
Review
London, United Kingdom. In Best Pract Res Clin Haematol, 2008
These strategies include the use of vaccines against minor histocompatibility antigens (HA-1, HA-2 and H-Y) and leukaemia-specific antigens (proteinase 3, Wilms' tumour 1 and BCR-ABL), and the adoptive transfer of leukaemia-specific T cells.
Immunotherapeutic strategies in acute lymphoblastic leukaemia relapsing after stem cell transplantation.
Review
Bristol, United Kingdom. In Blood Rev, 2005
Alternatively, immunotherapeutic strategies might exploit differences in minor histocompatibility antigens such as HA-1 and HA-2 between donor and recipient.
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.
Impact
San Diego, United States. In Nat Med, 2004
Using this information, we developed a transducible, pH-sensitive, fusogenic dTAT-HA2 peptide that markedly enhanced TAT-Cre escape from macropinosomes.
In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens.
Impact
Newcastle upon Tyne, United Kingdom. In Nat Med, 2002
Therefore, using a skin-explant assay we investigated the in situ activities of cytotoxic T lymphocytes (CTLs) specific for the ubiquitously expressed mHag H-Y and for the hematopoietic-restricted mHags HA-1 and HA-2.
Atomic structure of the ectodomain from HIV-1 gp41.
Impact
Boston, United States. In Nature, 1997
These features, and the existence of a similar reversal of chain direction in the fusion pH-induced conformation of influenza virus HA2 and in the transmembrane subunit of Moloney murine leukaemia virus (Fig. 1a-d), suggest a common mechanism for initiating fusion.
