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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 29 Jul 2015.

Myosin IG

HA2, K32
MYO1G is a plasma membrane-associated class I myosin (see MIM 601478) that is abundant in T and B lymphocytes and mast cells (Pierce et al., 2001 [PubMed 11544309]; Patino-Lopez et al., 2010 [PubMed 20071333]).[supplied by OMIM, Jun 2010] (from NCBI)
Top mentioned proteins: AE1, ACID, CAN, HAD, CD45
Papers on HA2
Eliciting neutralizing antibodies against the membrane proximal external region of HIV-1 Env by chimeric live attenuated influenza A virus vaccines.
Jiang et al., Changchun, China. In Vaccine, 31 Aug 2015
Here we engrafted the MPER into the linker domain between the trimeric core structure and the transmembrane domain of influenza A virus HA2 to investigate the potential of such chimeric viruses to elicit HIV-1 neutralizing antibodies.
Programming of Influenza Vaccine Broadness and Persistence by Mucoadhesive Polymer-Based Adjuvant Systems.
Lim et al., Suwŏn, South Korea. In J Immunol, 27 Aug 2015
In this study, we successfully generated a novel anti-influenza vaccine system combining conserved matrix protein 2 (sM2) and stalk domain of hemagglutinin (HA2) fusion protein (sM2HA2) and poly-γ-glutamic acid (γ-PGA)-based vaccine adjuvant systems that can act as a mucoadhesive delivery vehicle of sM2HA2 as well as a robust strategy for the incorporation of hydrophobic immunostimulatory 3-O-desacyl-4'-monophosphoryl lipid A (MPL) and QS21.
Mucosally administered Lactobacillus surface-displayed influenza antigens (sM2 and HA2) with cholera toxin subunit A1 (CTA1) Induce broadly protective immune responses against divergent influenza subtypes.
Kim et al., Taejŏn, South Korea. In Vet Microbiol, 17 Aug 2015
In this study, we constructed and expressed conserved sM2 and HA2 influenza antigens with cholera toxin subunit A1 (CTA1) on the surface of Lactobacillus casei (pgsA-CTA1sM2HA2/L.
DKK1 eukaryotic expression plasmid and expression product identification.
Xu et al., Yangzhou, China. In Genet Mol Res, Dec 2014
Using these fragments, we prepared the recombinant plasmid pCMV-HA2/DKK1.
A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Donis et al., Beijing, China. In Nat Commun, Dec 2014
X-ray crystallographic data reveal that CT149 binds primarily to the fusion domain in HA2, and the light chain is also largely involved in binding.
[Advances in research and development of universal influenza vaccines].
He et al., In Bing Du Xue Bao, 2014
This review describes the research progress in conserved epitopes of influenza virus, the advances in the research and development of universal influenza vaccines based on the relatively conserved sequences of NP, M2e, HA2, and headless HA, the mechanisms of cross-protection, and the methods to improve cross-protection.
New vaccines against influenza virus.
Kang et al., Atlanta, United States. In Clin Exp Vaccine Res, 2014
The strategies of universal vaccines include the matrix 2 protein, the hemagglutinin HA2 stalk domain, and T cell-based multivalent antigens.
Influenza virus hemagglutinin as a vaccine antigen produced in bacteria.
Sączyńska, Warsaw, Poland. In Acta Biochim Pol, 2013
The vast majority of bacterial HAs have been based on the HA1 subunit of HA expressed separately or as a component of conjugate vaccines, but those based on the ectodomain and the HA2 subunit have also been reported.
Protective immunity based on the conserved hemagglutinin stalk domain and its prospects for universal influenza vaccine development.
Rajput et al., Delhi, India. In Biomed Res Int, 2013
Its HA2 subunit (stem domain) is most conserved as compared to HA1 subunit (globular head domain).
Structural biology of the influenza virus fusion peptide.
Worch, Warsaw, Poland. In Acta Biochim Pol, 2013
The fusion is mediated by the influenza hemagglutinin protein (HA), in particular by the fusion peptide (HAfp) located in the N-terminal fragment of HA2 subunit.
DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.
Liu et al., Houston, United States. In Immunity, 2011
Although DDX1 bound poly I:C via its Helicase A domain, DHX36 and DDX21 bound the TIR domain of TRIF via their HA2-DUF and PRK domains, respectively.
Minor histocompatibility antigen HA-1 and HA-2 polymorphisms in Taiwan: frequency and application in hematopoietic stem cell transplantation.
Yang et al., Taipei, Taiwan. In Clin Chem Lab Med, 2010
the information on allele and genotype frequencies of HA-1 and HA-2 in a Taiwanese population
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).
Shaw et al., Bethesda, United States. In J Biol Chem, 2010
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain
Mismatch for the minor histocompatibility antigen HA-2 and GVHD occurrence in HLA-A*0201-positive Tunisian recipients of HSCs.
Hmida et al., Tunisia. In Immunol Invest, 2009
gene polymorphism does not have any significant effect on the occurrence of GVHD in Tunisia
Antibody recognition of a highly conserved influenza virus epitope.
Wilson et al., Los Angeles, United States. In Science, 2009
In contrast to other structurally characterized influenza antibodies, CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1 and HA2.
Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.
Dowdy et al., San Diego, United States. In Nat Med, 2004
Using this information, we developed a transducible, pH-sensitive, fusogenic dTAT-HA2 peptide that markedly enhanced TAT-Cre escape from macropinosomes.
In situ dissection of the graft-versus-host activities of cytotoxic T cells specific for minor histocompatibility antigens.
Goulmy et al., Newcastle upon Tyne, United Kingdom. In Nat Med, 2002
Therefore, using a skin-explant assay we investigated the in situ activities of cytotoxic T lymphocytes (CTLs) specific for the ubiquitously expressed mHag H-Y and for the hematopoietic-restricted mHags HA-1 and HA-2.
Atomic structure of the ectodomain from HIV-1 gp41.
Wiley et al., Boston, United States. In Nature, 1997
These features, and the existence of a similar reversal of chain direction in the fusion pH-induced conformation of influenza virus HA2 and in the transmembrane subunit of Moloney murine leukaemia virus (Fig. 1a-d), suggest a common mechanism for initiating fusion.
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