Role for DNA Damage Signaling in Pulmonary Arterial Hypertension.
Québec, Canada. In Circulation, 22 Dec 2013
RESULTS: Human PAH distal pulmonary arteries and cultured PAH-PASMC exhibit increased DNA damage markers (53BP1 & γ-H2AX) as well as an overexpression of PARP-1 (immunoblot & activity assay), compared to healthy tissues/cells.
Histone variants in pluripotency and disease.
Seattle, United States. In Development, Jun 2013
Furthermore, various H2A variants participate in DNA repair, gene regulation and other processes that are, as yet, not fully understood.
The polycomb complex PRC1: composition and function in plants.
Strasbourg, France. In J Genet Genomics, Jun 2013
PRC2 induces histone H3 lysine 27 (H3K27) trimethylation (H3K27me3), which is subsequently read by PRC1 that further catalyzes H2A monoubiquitination (H2Aub1), creating a transcriptional silent chromatin conformation.
Characterization of pea histone deacetylases.
Burjassot, Spain. In Plant Mol Biol, 1988
In vitro experiments with free histones show that HD0 deacetylates all four core histones, whereas HD1 and HD2 show a clear preference for H2A and H2B, the arginine-rich histones being deacetylated more slowly.
Chromosomal proteins of Arabidopsis thaliana.
More papers using
Raleigh, United States. In Plant Mol Biol, 1988
In plants with large genomes, each of the classes of the histones (H1, H2A, H2B, H3 and H4) are not unique polypeptides, but rather families of closely related proteins that are called histone variants.
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster.
In PLoS ONE, 2005
... Cruz Biotechnology), Ki67 (Lab Vision, Fremont, CA, USA); mouse monoclonal antibodies for phosphor-H2AX, Ser 139, (γH2AX) (BioLegend, San Diego, CA, USA), ... Histochemical localization of alkaline phosphatase activity in decalcified bone and cartilage
In Scientific Reports, 2001
... Primary antibodies CD34, CD44, CD105, CD29, SCA-1, CD45, osteocalcin, 53BP1, γ-H2AX, were purchased from Santa Cruz Biotechnology Inc (Santa Cruz, CA) ...