gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Glycosyltransferase 6 domain containing 1

GT6m7, GLT6D1
The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) [PubMed 19218399]).[supplied by OMIM, Jan 2011] (from NCBI)
Top mentioned proteins: glycosyltransferase, PCNA, Alpha-1, FS, Tec
Papers on GT6m7
Replication of the association of GLT6D1 with aggressive periodontitis in a Sudanese population.
New
El Karim et al., Khartoum, Sudan. In J Clin Periodontol, Apr 2015
RESULTS: One candidate gene rs1537415 (GLT6D1) was significantly associated with AgP, OR = 1.50 (95% CI 1.04-2.17),
Moving into a new era of periodontal genetic studies: relevance of large case-control samples using severe phenotypes for genome-wide association studies.
Review
Loos et al., Kuala Lumpur, Malaysia. In J Periodontal Res, 2014
However, susceptibility genes, such as CDKN2BAS (Cyclin Dependend KiNase 2B AntiSense RNA; alias ANRIL [ANtisense Rna In the Ink locus]), glycosyltransferase 6 domain containing 1 (GLT6D1) and cyclooxygenase 2 (COX2), have been reported as conclusive risk loci of periodontitis.
A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.
GeneRIF
Schreiber et al., Kiel, Germany. In Hum Mol Genet, 2010
GLT6D1 is a susceptibility locus for periodontitis.
Human pseudogenes of the ABO family show a complex evolutionary dynamics and loss of function.
Blancher et al., Barcelona, Spain. In Glycobiology, 2009
Here, we analyze the human GT6 pseudogene sequences (Forssman, IGB3, GGTA1, GT6m5, GT6m6, and GT6m7) from an evolutionary perspective, by the study of (i) their diversity levels in populations through the resequencing analysis of European and African individuals; (ii) the interpopulation differentiation, with genotyping data from a survey of populations covering most of human genetic diversity; and (iii) the interespecific divergence, by the comparison of the human and some other primate species sequences.
Long-term evolution of the CAZY glycosyltransferase 6 (ABO) gene family from fishes to mammals--a birth-and-death evolution model.
Blancher et al., Toulouse, France. In Glycobiology, 2007
In rat, mouse, dog, and cow genomes, we have identified three new mammalian genes (GT6m5, GT6m6, and GT6m7) encoding putative proteins belonging to the GT6 family.
share on facebooktweetadd +1mail to friends