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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CXCL2 chemokine (C-X-C motif) ligand 2

GRO-beta, GROX
Top mentioned proteins: IL-8, IL-1beta, Interleukin-6, MIP, CAN
Papers on GRO-beta
Dysregulated macrophage-inflammatory protein-2 expression drives illness in bacterial superinfection of influenza.
Stampfli et al., Hamilton, Canada. In J Immunol, 2010
To that end, neutralization of the ELR(+) inflammatory chemokine MIP-2 (CXCL2/GRO-beta) attenuated the inflammation, weight loss, and clinical presentation of heterologously infected mice without impacting bacterial burden.
Streptococcus agalactiae CspA is a serine protease that inactivates chemokines.
Shelver et al., Shreveport, United States. In J Bacteriol, 2009
In this study, we purified CspA and demonstrated that it readily cleaved the CXC chemokines GRO-alpha, GRO-beta, GRO-gamma, neutrophil-activating peptide 2 (NAP-2), and granulocyte chemotactic protein 2 (GCP-2) but did not cleave interleukin-8.
C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor alpha, on human monocytes.
Longrois et al., Nancy, France. In Thromb Haemost, 2008
CRP increased significantly the expression of the cytokines interleukin (IL)-1alpha, IL-1beta and IL-6, and the chemokines GRO-alpha, GRO-beta and IL-8.
Identification and characterization of a new interleukin-8 receptor in bovine species.
Riollet et al., France. In Mol Immunol, 2008
This was confirmed by binding assays with labeled IL-8 and GRO-beta and calcium (Ca) flux responses of transfected cells.
L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion.
Ballantyne et al., Houston, United States. In Atherosclerosis, 2007
mRNA consistently upregulated by L5 included VCAM-1 (2.3-fold) and CXC chemokines GRO-alpha (2.3), GRO-beta (4.6), IL-8 (2.5), ENA-78 (2.3), GRO-gamma (1.6) and GCP-2 (1.5).
Differential cytokine and chemokine responses of bovine mammary epithelial cells to Staphylococcus aureus and Escherichia coli.
Riollet et al., France. In Cytokine, 2007
Transcriptional levels and/or protein release of interleukin-8 (IL-8), growth related oncogene alpha (GRO-alpha), growth related oncogene beta (GRO-beta), tumor necrosis factor alpha (TNF-alpha), interleukin-1beta (IL-1beta), transforming growth factor beta1 (TGF-beta1) and interleukin-10 (IL-10) were measured at 3, 10 and 24h post-infection (PI).
Cytokine gene expression profiles in human lymphocytes induced by a formula of traditional Chinese medicine, vigconic VI-28.
Hammarström et al., Huddinge, Sweden. In J Interferon Cytokine Res, 2006
The VI-28 treatment induced expression of a number of proinflammatory cytokines/chemokines in both peripheral blood mononuclear cells (PBMC) and spleen cells, including interleukin-1 (IL-1), growth-related protein-beta (GRO-beta) and epithelial cellderived neutrophil-activating peptide (ENA-78 [CXCL5]).
Conjunctival cytokine expression in symptomatic moderate dry eye subjects.
McDermott et al., Houston, United States. In Invest Ophthalmol Vis Sci, 2006
TRAIL was constitutively expressed in CIC samples, whereas IL-1beta, IL-6, and GRO-beta were absent.
Differential gene expression in activated monocyte-derived macrophages following binding of factor VIIa to tissue factor.
Hölschermann et al., Gießen, Germany. In Thromb Haemost, 2005
Of the 1176 genes examined on the array, a small set of six genes (IL-6, IL-8,TNF-a, GRO-beta alpha-thymosin, cathepsin H) were consistently up-regulated and one gene suppressed (alpha-antitrypsin) in response to FVIIa in activated monocyte-derived macrophages.
NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments.
Loeser et al., Chicago, United States. In J Immunol, 2005
Compared with untreated control cultures, stimulation by FN-f resulted in a >2-fold increase in IL-6, IL-8, MCP-1, and growth-related oncogene beta (GRO-beta).
Differential gene expression during capillary morphogenesis in a microcarrier-based three-dimensional in vitro model of angiogenesis with focus on chemokines and chemokine receptors.
Ding et al., Nanjing, China. In World J Gastroenterol, 2005
As for chemokines and chemokine receptors, CXCL1/GRO-alpha, CXCL2/GRO-beta, CXCL5/ENA-78, CXCL6/GCP2, IL-8/CXCL8, CXCL12/SDF-1, CXCL9/Mig, CXC11/ITAC, CX3CL1/fractalkine, CCL2/MCP-1, CCL3, CCL5/RANTES, CCL7, CCL15, CCL21, CCL23, CCL28, and CCR1, CCR9, CXCR4 were identified.
The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.
Schlievert et al., Minneapolis, United States. In Infect Immun, 2005
In response to S. aureus, the HVEC genes most up-regulated compared to those in controls were those coding for chemokines or cytokines--MIP-3alpha, 478-fold; GRO-alpha, 26-fold; GRO-beta, 14-fold; and GRO-gamma, 30-fold--suggesting activation of innate immunity.
The effects and comparative differences of neutrophil specific chemokines on neutrophil chemotaxis of the neonate.
Calhoun et al., Saint Petersburg, United States. In Cytokine, 2005
Specifically, at 100 ng/mL, the order was IL-8/CXCL8>GRO-alpha/CXCL1>GCP-2/CXCL6>NAP-2/CXCL7>ENA-78/CXCL5>GRO-gamma/CXCL2>GRO-beta/CXCL3.
The effect of interleukin-1 on cytokine gene expression by human corneal epithelial cells.
McDermott et al., Houston, United States. In Exp Eye Res, 2005
Reverse transcription polymerase chain reaction (RT-PCR) was performed to detect mRNA for IL-8, growth related oncogene-beta (GRO-beta), intercellular adhesion molecule (ICAM)-1 and Ephrin A5.
Chemokine expression in the monocytic cell line THP-1 in response to purified shiga toxin 1 and/or lipopolysaccharides.
Tesh et al., College Station, United States. In Infect Immun, 2005
A cytokine macroarray analysis of transcripts derived from macrophage-like THP-1 cells treated with Stx1, lipopolysaccharides (LPS), or both demonstrated a consistent up-regulation of TNF-alpha, IL-1beta, and four genes encoding the chemokines interleukin-8 (IL-8), macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, and growth-related oncogene beta (GRO-beta).
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