A tale of two kinases in rods and cones.
Chapel Hill, United States. In Adv Exp Med Biol, 2011
Defects in GRK1 or GRK7 cause patients to suffer from an inability to properly deactivate rhodopsin leading to problems with recovery and dark adaptation.
Larger inhibition of visual pigment kinase in cones than in rods.
Suita, Japan. In J Neurochem, 2010
In the carp retina, visual pigment kinase, GRK1 (G-protein coupled receptor kinase 1) in rods and GRK7 in cones, is inhibited by a photoreceptor neuronal Ca(2+)-sensor protein, S-modulin (or recoverin) in rods and visinin (formerly named s26) in cones.