A novel monoclonal antibody against human GRK6 antigen.
Chengdu, China. In Monoclon Antib Immunodiagn Immunother, Feb 2015
G protein-coupled receptor kinase 6 (GRK6) plays a universal role in receptor desensitization, by acting as a receptor-G protein interface, thereby affecting serine/threonine kinases.
[Research on Molecular Mechanisms of Engulfment of Apoptotic Cells].
In Yakugaku Zasshi, 2014
We further determined that G protein-coupled receptor kinase 6 (GRK6), originally identified as a kinase responsible for the desensitization and downregulation of G-protein-coupled receptors, activates Rac1 independent of the two known intracellular engulfment pathways in phagocytes.
Non-visual GRKs: are we seeing the whole picture?
Leicester, United Kingdom. In Trends Pharmacol Sci, 2003
However, recent work has indicated roles for the other, non-visual GRKs (GRK4, GRK5 and GRK6) and has revealed potential phosphorylation-independent regulation of GPCRs by GRK2 and GRK3.