Recurrent activating mutations of CD28 in peripheral T-cell lymphomas.
Xi'an, China. In Leukemia, Jan 2016
Surface plasmon resonance analysis of mutations at these residues with predicted differential partner interactions showed increased affinity for ligand CD86 (residue D124) and increased affinity for intracellular adaptor proteins GRB2 and GADS/GRAP2 (residue T195).
The safety of regorafenib for the treatment of gastrointestinal stromal tumors.
Warsaw, Poland. In Expert Opin Drug Saf, Jan 2016
AREAS COVERED: Regorafenib, an oral multitargeted inhibitor with activity against multiple kinases including KIT, RET, RAF1, BRAF, angiogenesis (VEGFR, TIE-2) and those involved in tumor microenvironment (PDGFR and FGFR) was introduced after the successful Phase III GRID (GIST - Regorafenib In progressive Disease) clinical trial.
[A review of face illusions].
Kyoto, Japan. In Brain Nerve, 2012
The "gaze illusion" or the illusion of eye direction includes the Wollaston illusion, the luminance-induced gaze shift, the Bogart illusion, the eye-shadow-dependent gaze illusion, the Mona Lisa effect, etc. "Face inversion effects" refer to the Thatcher illusion, the fat face-thin illusion, underestimation of the upright face, the nose-shortening illusion of the inverted face, etc. "Geometrical illusions" include the Lee-Freire illusion, Yang's iris illusion, overestimation of the farther eye, the eye-shadow-dependent eye-size illusion, etc. "Reversible figures" contain the whole-part reversible figure, Rubin's vase-face illusion, or hybrid images.