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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Glutathione peroxidase 7

GPX7, GPX-6, NPGPx, non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase
Top mentioned proteins: phospholipid hydroperoxide glutathione peroxidase, CAN, Interleukin-6, ACID, HAD
Papers on GPX7
Protective Effect of Peroxiredoxin 6 in Ischemia/Reperfusion-Induced Damage of Small Intestine.
New
Novoselov et al., Moscow, Russia. In Dig Dis Sci, Dec 2015
Expression analysis of genes coding for major antioxidant enzymes demonstrated a significant activation of SOD 1, SOD 3, Prx6, GPx2, GPx7 expression during I/R-induced damage of the small intestine.
NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress.
New
Lee et al., Taipei, Taiwan. In Nucleic Acids Res, Nov 2015
Non-selenocysteine-containing phospholipid hydroperoxide glutathione peroxidase (NPGPx or GPx7) is an oxidative stress sensor that modulates the antioxidative activity of its target proteins through intermolecular disulfide bond formation.
Understanding mammalian glutathione peroxidase 7 in the light of its homologs.
Review
New
Ursini et al., Padova, Italy. In Free Radic Biol Med, Jun 2015
Mammalian GPx7 and GPx8 are unique homologs that contain a peroxidatic Cys (CP).
Comparison of the deleterious effects of binge drinking-like alcohol exposure in adolescent and adult mice.
New
Vaudry et al., Mont-Saint-Aignan, France. In J Neurochem, Mar 2015
In adolescent animals, alcohol decreased the expression of genes involved in the repair and protection of oxidative DNA damage such as atr, gpx7, or nudt15 and increased the expression of proapoptotic genes such as casp3.
Effects of methionine supplementation on the expression of oxidative stress-related genes in acute heat stress-exposed broilers.
New
Neto et al., Colombo, Brazil. In Br J Nutr, Mar 2015
The aim of the present study was to evaluate the effects of heat stress (HS) and methionine supplementation on the markers of stress and on the gene expression levels of uncoupling proteins (UCP), betaine-homocysteine methyltransferase (BHMT), cystathionine β-synthase (CBS), glutathione synthetase (GSS) and glutathione peroxidase 7 (GPx7).
Candidate pathway-based genetic association study of platinum and platinum-taxane related toxicity in a cohort of primary lung cancer patients.
New
Yang et al., Rochester, United States. In J Neurol Sci, Mar 2015
SNPs most associated with CIPN were in glutathione peroxidase 7 (GPX7) gene (p values 0.0015 and 0.0028, unadjusted and adjusted) and in ATP-binding cassette sub-family C member 4 (ABCC4) gene (p values 0.037 and 0.006, unadjusted and adjusted).
Evaluation of the selenotranscriptome expression in two hepatocellular carcinoma cell lines.
Costantini et al., Napoli, Italy. In Anal Cell Pathol (amst), 2014
Our data showed that in both cells there are three downregulated (DIO1, DIO2, and SELO) and ten upregulated (GPX4, GPX7, SELK, SELM, SELN, SELT, SELV, SEP15, SEPW1, and TrxR1) genes.
GPX4 and GPX7 over-expression in human hepatocellular carcinoma tissues.
Costantini et al., Al Qubbah, Libya. In Eur J Histochem, 2014
In this paper we have evaluated the GPX4 and GPX7 expression in some paraffin-embedded tissues from liver biopsy of patients with hepatitis C virus (HCV)-related cirrhosis and HCC by immunohistochemistry and RT-qPCR analysis.
Dietary sodium selenite affects host intestinal and systemic immune response and disease susceptibility to necrotic enteritis in commercial broilers.
Bravo et al., Qingdao, China. In Br Poult Sci, 2014
The effects of dietary Se on the gene expression of pro-inflammatory cytokines e.g., interleukin (IL)-1β, IL-6, IL-8LITAF (lipopolysaccharide-induced TNFα-factor), tumour necrosis factor (TNF) SF15, and inducible nitric oxide synthase (iNOS), glutathione peroxidase 7 (GPx7), and avian β-defensins (AvBD) 6, 8, and 13 (following NE infection) were analysed in the intestine and spleen.
An amphiphilic selenide catalyst behaves like a hybrid mimic of protein disulfide isomerase and glutathione peroxidase 7.
Iwaoka et al., Hiratsuka, Japan. In Chem Asian J, 2014
Protein disulfide isomerase (PDI) and glutathione peroxidase 7 (GPx7) cooperatively promote the oxidative folding of disulfide (SS)-containing proteins in endoplasmic reticulum by recognizing the nascent proteins to convert them into the native folds by means of SS formation and SS isomerization and by catalyzing reoxidation of reduced PDI with H2O2, respectively.
Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.
Ling et al., Malmö, Sweden. In Plos Genet, 2014
Functional analyses further demonstrated that identified candidate genes (GPX7, GSTT1 and SNX19) directly affect key biological processes such as proliferation and apoptosis in pancreatic β-cells.
Validation of DNA promoter hypermethylation biomarkers in breast cancer--a short report.
Moelans et al., Utrecht, Netherlands. In Cell Oncol (dordr), 2014
METHODS: The methylation status of a panel of 19 candidate genes (AKR1B1, ALX1, ARHGEF7, FZD10, GHSR, GPX7, GREM1, GSTP1, HOXD1, KL, LHX2, MAL, MGMT, NDRG2, RASGRF2, SFRP1, SFRP2, TM6SF1 and TMEFF2) was determined in formalin-fixed paraffin-embedded normal breast and breast cancer tissue samples using gel-based methylation-specific PCR (MSP).
Glutathione Peroxidase 7 Suppresses Bile Salt-Induced Expression of Pro-Inflammatory Cytokines in Barrett's Carcinogenesis.
El-Rifai et al., Nashville, United States. In J Cancer, 2013
Glutathione peroxidase 7 (GPX7) is frequently silenced through DNA hypermethylation during Barrett's tumorigenesis.
Glutathione peroxidases.
Review
Maiorino et al., Germany. In Biochim Biophys Acta, 2013
Functions of GPx6 are still unknown, and the proposed involvement of GPx7 and GPx8 in protein folding awaits elucidation.
Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum.
Review
Appenzeller-Herzog et al., Basel, Switzerland. In Int J Cell Biol, 2012
This review discusses the properties and physiological roles of PrxIV, GPx7, and GPx8 in the endoplasmic reticulum (ER) of higher eukaryotic cells where H2O2 and-possibly-lipid hydroperoxides are regularly produced.
Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation.
GeneRIF
Ruddock et al., Oulu, Finland. In J Mol Biol, 2011
GPx7 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase
Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells.
GeneRIF
Lee et al., Irvine, United States. In J Biol Chem, 2004
NPGPx plays an essential role in breast cancer cells in alleviating oxidative stress generated from polyunsaturated fatty acid metabolism
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