gopubmed logo
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

G protein-coupled receptor 20

Top mentioned proteins: GPR21, GPR22, GPR18, GPR58, GPR119
Papers on GPR20
APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease.
Arcos-Burgos et al., Canberra, Australia. In Mol Psychiatry, Jan 2016
Exploratory linear mixed-effects multilocus analysis suggested that other functional variants harbored in genes involved in cell proliferation, protein degradation, apoptotic and immune dysregulation processes (i.e., GPR20, TRIM22, FCRL5, AOAH, PINLYP, IFI16, RC3H1 and DFNA5) might interact with the APOE*E2 allele.
Constitutive Activity among Orphan Class-A G Protein Coupled Receptors.
Aronstam et al., Rolla, United States. In Plos One, 2014
Five patterns of activity were noted: 1) inhibition under both baseline and forskolin stimulated expression (GPR15, GPR17, GPR18, GPR20, GPR25, GPR27, GPR31, GPR32, GPR45, GPR57, GPR68, GPR83, GPR84, GPR132, GPR150, GPR176); 2) no effect on baseline expression, but inhibition of forskolin stimulated expression (GPR4, GPR26, GPR61, GPR62, GPR78, GPR101, GPR119); 3) elevation of baseline signaling coupled with inhibition of forskolin stimulated expression (GPR6, GPR12); 4) elevation of baseline signaling without inhibition of forskolin stimulated expression (GPR3, GPR21, GPR52, GPR65); and 5) no effect on expression (GPR1, GPR19, GPR22, GPR34, GPR35, GPR39, GPR63, GPR82, GPR85, GPR87).
Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteins.
Nakamura et al., Tokyo, Japan. In J Biol Chem, 2008
GPR20 constitutively activates G(i) proteins without ligand stimulation
Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes.
George et al., Toronto, Canada. In Gene, 1997
Gene GPR20 was isolated by amplifying genomic DNA with oligos based on the opioid and somatostatin related receptor genes and subsequent screening of a genomic library.
share on facebooktweetadd +1mail to friends