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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

G protein-coupled receptor 101

GPR101, G protein-coupled receptor 101
Top mentioned proteins: HAD, AGE, CAN, GPCR, V1a
Papers on GPR101
Growth hormone releasing hormone excess and blockade in X-LAG syndrome.
New
Beckers et al., Brussels, Belgium. In Endocr Relat Cancer, Jan 2016
including the GPR101 gene cause X-LAG syndrome.
Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome.
New
Beckers et al., Brasília, Brazil. In Endocrine, Dec 2015
leading to copy number gain of GPR101.
GnRH-(1-5) activates matrix metallopeptidase-9 to release epidermal growth factor and promote cellular invasion.
New
Wu et al., Bethesda, United States. In Mol Cell Endocrinol, Dec 2015
GnRH-(1-5) acts on the orphan G protein-coupled receptor 101 (GPR101) to sequentially stimulate epidermal growth factor (EGF) release, phosphorylate the EGF receptor (EGFR), and facilitate cellular migration.
X-linked acrogigantism syndrome: clinical profile and therapeutic responses.
New
Stratakis et al., Vancouver, Canada. In Endocr Relat Cancer, Jun 2015
encompassing the gene GPR101, which is highly upregulated in pituitary tumors.
Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation.
Impact
Stratakis et al., Aş Şanamayn, Syria. In N Engl J Med, 2015
Only one of these genes, GPR101, which encodes a G-protein-coupled receptor, was overexpressed in patients' pituitary lesions.
Constitutive Activity among Orphan Class-A G Protein Coupled Receptors.
Aronstam et al., Rolla, United States. In Plos One, 2014
Five patterns of activity were noted: 1) inhibition under both baseline and forskolin stimulated expression (GPR15, GPR17, GPR18, GPR20, GPR25, GPR27, GPR31, GPR32, GPR45, GPR57, GPR68, GPR83, GPR84, GPR132, GPR150, GPR176); 2) no effect on baseline expression, but inhibition of forskolin stimulated expression (GPR4, GPR26, GPR61, GPR62, GPR78, GPR101, GPR119); 3) elevation of baseline signaling coupled with inhibition of forskolin stimulated expression (GPR6, GPR12); 4) elevation of baseline signaling without inhibition of forskolin stimulated expression (GPR3, GPR21, GPR52, GPR65); and 5) no effect on expression (GPR1, GPR19, GPR22, GPR34, GPR35, GPR39, GPR63, GPR82, GPR85, GPR87).
Conditional targeting of medium spiny neurons in the striatal matrix.
Kullander et al., Uppsala, Sweden. In Front Behav Neurosci, 2014
Here, we present a transgenic mouse line, Gpr101-Cre, with Cre recombinase activity localized to matrix D1 and D2 MSNs.
GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor.
Wu et al., Houston, United States. In Mol Endocrinol, 2014
In addition, we also demonstrate that these actions of GnRH-(1-5) are mediated by the orphan G protein-coupled receptor 101 (GPR101).
Methyl-CpG binding column-based identification of nine genes hypermethylated in colorectal cancer.
Siedlecki et al., Warsaw, Poland. In Mol Carcinog, 2011
The frequency of their promoter methylation was assessed in the larger group of patients (n = 77): KCNK12 (methylated in 41% of CRC patients), GPR101 (40%), CDH2 (45%), BARX1 (56%), CNTFR (22%), SYT6 (64%), SMO (21%), EPHA5 (43%), and GSPT2 (21%).
G protein-coupled receptor 101 mRNA expression in supraoptic and paraventricular nuclei in rat hypothalamus is altered by pregnancy and lactation.
Barrett et al., Aberdeen, United Kingdom. In Brain Res, 2008
In a previous study performed in mouse models of energetic challenge, there was evidence to suggest that the orphan G protein-coupled receptor GPCR101 may have a role in the regulation of energy balance.
G protein-coupled receptor 101 mRNA expression in the mouse brain: altered expression in the posterior hypothalamus and amygdala by energetic challenges.
Barrett et al., Aberdeen, United Kingdom. In J Neuroendocrinol, 2007
GPCR101 is a recently identified orphan G protein-coupled receptor (GPCR) expressed abundantly in the human and mouse hypothalamus.
Characterization of Gpr101 expression and G-protein coupling selectivity.
GeneRIF
Pausch et al., Cambridge, United States. In Brain Res, 2006
murine Gpr101 mRNA was detected predominantly in the brain within discrete nuclei and that GPR101 participates in a potentially wide range of activities in the CNS via modulation of cAMP levels.
Discovery and mapping of ten novel G protein-coupled receptor genes.
O'Dowd et al., Toronto, Canada. In Gene, 2001
We report the identification, cloning and tissue distributions of ten novel human genes encoding G protein-coupled receptors (GPCRs) GPR78, GPR80, GPR81, GPR82, GPR93, GPR94, GPR95, GPR101, GPR102, GPR103 and a pseudogene, psi GPR79.
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