GPI-anchored membrane protein
Urokinase receptor and resistance to targeted anticancer agents.
San Diego, United States. In Front Pharmacol, 2014
The urokinase receptor (uPAR) is a GPI-anchored membrane protein, which regulates protease activity at the cell surface and, in collaboration with a system of co-receptors, triggers cell-signaling and regulates gene expression within the cell.
Predicting membrane protein type by functional domain composition and pseudo-amino acid composition.
Manchester, United Kingdom. In J Theor Biol, 2006
The overall success rates obtained with the FunD-PseAA predictor on such a data set by the jackknife cross-validation test was 85% for the case in identifying membrane protein and non-membrane protein, and 91% in identifying the membrane protein type among the following 5 categories: (1) type-1 membrane protein, (2) type-2 membrane protein, (3) multipass transmembrane protein, (4) lipid chain-anchored membrane protein, and (5) GPI-anchored membrane protein.