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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Golgin A2

GM130, golgin-95
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010] (from NCBI)
Top mentioned proteins: CIs, CAN, GRASP65, V1a, COPI
Papers using GM130 antibodies
Kdo2-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy*
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Merrill Alfred H. et al., In The Journal of Biological Chemistry, 2009
... 33342 (Invitrogen); ISP1 (Biomol, Plymouth Meeting, PA); mouse monoclonal antibody to SPT1 (anti-LCB1), anti-BiP/GRP78, and anti-GM130 (BD Biosciences); rabbit monoclonal anti-HA tag ...
A dynamic, cytoplasmic triacylglycerol pool in enterocytes revealed by ex vivo and in vivo coherent anti-Stokes Raman scattering imaging
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Demignot Sylvie et al., In Biology of the Cell, 2008
... Mouse monoclonal antibodies to calnexin, PDI and GM130 were from BD Biosciences.
Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins
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Munro Sean et al., In The Journal of Cell Biology, 2006
... ), and polyclonal rabbit anti-GM130 (1:3,000; Abcam) were used.
Pre- and post-Golgi translocation of glucosylceramide in glycosphingolipid synthesis
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Sprong Hein et al., In The Journal of Cell Biology, 2005
... anti-V5 antibody was purchased from Invitrogen, mouse mAb 16B12 anti-HA was obtained from BabCO, mouse anti-GM130 antibodies were obtained from BD Biosciences, and mouse anti–glyceraldehyde-3 phosphate ...
ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65
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Seemann Joachim et al., In The Journal of Cell Biology, 2005
... Monoclonal antibodies against GM130 (BD Biosciences), γ-tubulin (GTU-88; Sigma-Aldrich), and ...
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Papers on GM130
GOLGA2, encoding a master regulator of golgi apparatus, is mutated in a patient with a neuromuscular disorder.
New
Alkuraya et al., Riyadh, Saudi Arabia. In Hum Genet, Feb 2016
GOLGA2 encodes GM130, a necessary component for the assembly of GA as a single complex, and its deficiency has been found to result in severe cellular phenotypes.
Cylindrical Spirals in Skeletal Muscles Originate From the Longitudinal Sarcoplasmic Reticulum.
New
Yan et al., Jinan, China. In J Neuropathol Exp Neurol, Feb 2016
CSs exhibited no immunoreactivity for the Golgi apparatus marker GM130, the nuclear membrane emerin, desmin, the autophagosome marker LC3, the lysosomal membrane marker LAMP2, dystrophin, or myosin.
Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.
New
Tooze et al., London, United Kingdom. In Mol Cell, Jan 2016
Two Golgi proteins, WAC and GM130, regulate autophagy, however their mechanism of regulation is unknown.
Structural Basis for the Interaction between the Golgi Reassembly-stacking Protein GRASP65 and the Golgi Matrix Protein GM130.
New
Shi et al., Fuzhou, China. In J Biol Chem, Nov 2015
GM130 and GRASP65 are Golgi peripheral membrane proteins that play a key role in Golgi stacking and vesicle tethering.
GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.
New
Impact
Seemann et al., Dallas, United States. In Cell, Aug 2015
Upon mitotic entry, the Golgi matrix protein GM130 interacts with importin α via a classical nuclear localization signal that recruits importin α to the Golgi membranes.
GM130 regulates epithelial-to-mesenchymal transition and invasion of gastric cancer cells via snail.
Wu et al., China. In Int J Clin Exp Pathol, 2014
As a cis-Golgi matrix protein, GM130 plays an important role in cell cycle progression and transport of protein in the secretory pathway.
Endomembrane control of cell polarity: Relevance to cancer.
Review
Farhan et al., Konstanz, Germany. In Small Gtpases, 2014
In our recent work, we identified a complex between the Golgi matrix protein GM130 and RasGRF and showed that it is responsible for regulating the Golgi pool of Cdc42, but had no effect on the plasma membrane pool of Cdc42.
SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.
Review
Clerk et al., Reading, United Kingdom. In Biochem J, 2013
We explore the role(s) of GCKIIIs (and CCM3/PDCD10) in STRIPAK (striatin-interacting phosphatase and kinase) complexes and their association with the cis-Golgi protein GOLGA2 (golgin A2; GM130).
GM130, a cis-Golgi protein, regulates meiotic spindle assembly and asymmetric division in mouse oocyte.
GeneRIF
Sun et al., Guangzhou, China. In Cell Cycle, 2011
GM130 regulates microtubule organization and might cooperate with the MAPK pathway to play roles in spindle organization, migration and asymmetric division during mouse oocyte maturation
Reelin and stk25 have opposing roles in neuronal polarization and dendritic Golgi deployment.
Impact
Howell et al., Syracuse, United States. In Cell, 2010
We find that Stk25, a modifier of Reelin-Dab1 signaling, regulates Golgi morphology and neuronal polarization as part of an LKB1-Stk25-Golgi matrix protein 130 (GM130) signaling pathway.
Mitotic Golgi vesiculation involves mechanisms independent of Ser25 phosphorylation of GM130.
GeneRIF
Murata-Hori et al., Singapore, Singapore. In Cell Cycle, 2010
Serine 25 phosphorylation of GM130 independent pathways ensure Golgi vesiculation and mitotic progression.
Association of coagulation factor XIII-A with Golgi proteins within monocyte-macrophages: implications for subcellular trafficking and secretion.
GeneRIF
Grant et al., Leeds, United Kingdom. In Blood, 2010
FXIII-A associated with podosomes & other structures adjacent to the plasma membrane, containing TGN46 & GM130 but not protein disulphide isomerase. FXIII-A was present in GM130-positive intracellular vesicles that could mediate its transport.
Emerging new roles of GM130, a cis-Golgi matrix protein, in higher order cell functions.
Review
GeneRIF
Nakamura, Kanazawa, Japan. In J Pharmacol Sci, 2009
GM130 is involved in the control of glycosylation, cell cycle progression, cell polarization and directed cell migration, according to this review.
Microtubule nucleation at the cis-side of the Golgi apparatus requires AKAP450 and GM130.
GeneRIF
Rios et al., Sevilla, Spain. In Embo J, 2009
Data suggest that recruitment of AKAP450 on Golgi membranes through GM130 allows centrosome-associated nucleating activity to extend to the Golgi, to control the assembly of subsets of microtubules.
GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution.
Impact
GeneRIF
Linstedt et al., Pittsburgh, United States. In Nat Cell Biol, 2006
Ribbon formation requires the Golgi proteins GM130 and GRASP65.
Polycystin-2--an intracellular or plasma membrane channel?
Review
Witzgall, Regensburg, Germany. In Naunyn Schmiedebergs Arch Pharmacol, 2005
PIGEA-14 also interacts with GM130, a protein associated with the Golgi matrix, and may therefore represent one important component of the trafficking machinery for polycystin-2.
Autoantibodies to protein transport and messenger RNA processing pathways: endosomes, lysosomes, Golgi complex, proteasomes, assemblyosomes, exosomes, and GW bodies.
Review
Fritzler et al., Calgary, Canada. In Clin Immunol, 2004
Autoantigens in the Golgi complex include giantin/macrogolgin, golgin-245, golgin 160, golgin-97, golgin 95/gm130, and golgin-67.
The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment.
Impact
De Matteis et al., Chieti, Italy. In Nat Cell Biol, 2001
To gain insight into this step, we investigated the dynamics by which cis-Golgi matrix proteins such as GM130 and GRASP65 associate with, and incorporate, incoming IC elements.
Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis.
Impact
Warren et al., London, United Kingdom. In Cell, 1998
Mitotic fragmentation of the Golgi apparatus can be largely explained by disruption of the interaction between GM130 and the vesicle-docking protein p115.
More papers using GM130 antibodies
Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability
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Lupashin Vladimir et al., In The Journal of Cell Biology, 2004
... (WB 1:500; IF 1:100); anti-hCog3p (WB 1:1,000) and hCog8p (WB 1:3,000); p115 (WB 1:1,000); mouse anti-GM130 (WB 1:500; IF 1:250); anti–human GS28 (WB 1:500; IF 1:100; BD Biosciences); anti-Bet1 (WB 1:200; BD ...
Regulation of caveolin-1 membrane trafficking by the Na/K-ATPase
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Xie Zi-Jian et al., In The Journal of Cell Biology, 2004
... The antibodies used and their sources are as follows: the anti-Cav1 polyclonal antibody, anti-EEA-1, anti-GM130, goat anti–rabbit secondary antibody, and goat anti–mouse secondary antibody were obtained from Santa Cruz Biotechnology, Inc ...
Rer1p competes with APH-1 for binding to nicastrin and regulates γ-secretase complex assembly in the early secretory pathway
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Annaert Wim et al., In The Journal of Cell Biology, 2004
... NCT ectodomain (amino acids 168–289; BD Biosciences), the transferrin receptor (Tfr; cl H68.4; Zymed Laboratories), GM130 (BD Biosciences), and actin (cl AC-15; ...
Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis.
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Harris Reuben S., In PLoS ONE, 2003
... Anti-TGN46 (Abcam) and Anti-GM130 (Abcam) were used to detect ...
mBet3p is required for homotypic COPII vesicle tethering in mammalian cells
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Ferro-Novick Susan et al., In The Journal of Cell Biology, 2003
... Monoclonal antibody directed against GM130 was purchased from BD Biosciences.
Analysis of gene function in somatic mammalian cells using small interfering RNAs.
Supplier
Delprato Anna Maria, In PLoS ONE, 2001
... were kindly provided by Jennifer Hirst (CIMR, Cambridge, UK); rabbit polyclonal anti-giantin (Covance); monoclonal mouse anti-GM130 (BD Transduction Laboratories); polyclonal sheep anti-TGN46 (AbD Serotec); monoclonal mouse anti-RIIα PKA ...
Regulation of eNOS Expression in Brain Endothelial Cells by Perinuclear EP3 Receptors.
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Koch Karl-Wilhelm, In PLoS ONE, 2001
... (Oakville, ON, Canada), mouse anti-lamin A/C, and mouse anti-calnexin from AbCam (Cambridge, MA, USA), mouse anti-GM130 from Transduction Laboratories (BD Biosciences, Mississauga, ON, Canada), murine ...
The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment
Supplier
Lane J D et al., In Cell Death & Disease, 2000
... -tubulin (clone 6-11B-1), anti-TGN46 (AbD Serotec), anti-giantin (Covance), anti-GM130 (BD Biosciences), anti- ...
Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles
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Stamnes Mark et al., In The Journal of Cell Biology, 1999
... (BD Biosciences), and anti-GM130 (BD Biosciences).
A novel Rab GTPase, Rab33B, is ubiquitously expressed and localized to the medial Golgi cisternae
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Fukuda Mitsunori et al., In The Journal of Cell Biology, 1997
... Anti-GM130 mouse monoclonal antibody (BD), antiactin goat polyclonal antibody (Santa Cruz Biotechnology, Inc.), anti-Atg12 (or Apg12) ...
Ultrastructural identification of uncoated caveolin-independent early endocytic vehicles
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Parton Robert G. et al., In The Journal of Cell Biology, 1997
... Antibodies were obtained from the following sources: rabbit anti-caveolin and mouse anti-GM130 (BD Biosciences), rabbit anti-CT (Sigma-Aldrich), rabbit ...
The localization and phosphorylation of p47 are important for Golgi disassembly–assembly during the cell cycle
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Kondo Hisao et al., In The Journal of Cell Biology, 1991
... mAb to p97, His-tag, and GM130 were purchased from Progen, QIAGEN, and BD Transduction, respectively.
rab5 controls early endosome fusion in vitro.
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Wölfl Stefan, In PLoS ONE, 1990
... blot and supplied by Santa Cruz (anti-EGFR, dilution 4000), BD Transduction Laboratories (monoclonal anti-Itch and anti-GM130, diluted respectively 3000 and 800 fold), Abgent (polyclonal anti-Itch), Sigma (anti-Flag ...
Morphological classification of rat incisor ameloblasts
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Abe Michio et al., In Frontiers in Physiology, 1973
... Some sections were incubated with mouse monoclonal anti-GM130 antibody (clone 35/GM130, BD Biosciences, CA, USA) at a concentration ...
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