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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Chromosome 3 open reading frame 39

glycosyltransferase
Top mentioned proteins: ACID, CAN, V1a, HAD, fibrillin-1
Papers on glycosyltransferase
Biophysical characterization and activity of lymphostatin, a multifunctional virulence factor of attaching & effacing Escherichia coli.
New
Stevens et al., United Kingdom. In J Biol Chem, Feb 2016
The largest proteolytic fragment containing the putative glycosyltransferase domain was tested in isolation for activity against T cells, and was not sufficient for activity.
The UDP-glycosyltransferase (UGT) superfamily expressed in humans, insects and plants: Animal-plant arms-race and co-evolution.
Review
New
Bock, Tübingen, Germany. In Biochem Pharmacol, Feb 2016
UDP-glycosyltransferases (UGTs) are major phase II enzymes of a detoxification system evolved in all kingdoms of life.
Sequential Notch activation regulates ventricular chamber development.
New
Impact
de la Pompa et al., Madrid, Spain. In Nat Cell Biol, Jan 2016
We show that Notch signalling first connects chamber endocardium and myocardium to sustain trabeculation, and later coordinates ventricular patterning and compaction with coronary vessel development to generate the mature chamber, through a temporal sequence of ligand signalling determined by the glycosyltransferase manic fringe (MFng).
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.
New
West et al., United States. In J Biol Chem, Jan 2016
Reconstitution of the glycosyltransferase reactions in extracts with radioactive sugar nucleotide substrates and appropriate Skp1 glycoforms, followed by chromatographic analysis of acid hydrolysates of the reaction products, confirmed the predicted sugar identities as GlcNAc, Gal and Fuc.
Phylogeny, structure, function, biosynthesis and evolution of sulfated galactose-containing glycans.
Review
New
Pomin, Rio de Janeiro, Brazil. In Int J Biol Macromol, Jan 2016
Although future investigations in molecular biology must be still performed in order to assure certain hypotheses, empirical evidences based on structural biology of the sulfated galactose-containing glycans among different species particularly their backbone and sulfation patterns clearly indicate great specificity in terms of glycosyltransferase and sulfotransferase activity.
Production of γ-cyclodextrin by Bacillus cereus cyclodextrin glycosyltransferase using extractive bioconversion in polymer-salt aqueous two-phase system.
New
Ling et al., Kuala Lumpur, Malaysia. In J Biosci Bioeng, Jan 2016
Extractive bioconversion of gamma-cyclodextrin (γ-CD) from soluble starch with cyclodextrin glycosyltransferase (CGTase, EC 2.4.1.19)
Identification and characterisation of a biosynthetic locus for Moraxella bovis lipo-oligosaccharide.
New
Peak et al., Gold Coast, Australia. In Carbohydr Res, Jan 2016
Mutation of these putative glycosyltransferase genes resulted in M. bovis mutant bacteria that expressed truncated LOS structures.
Sucrose synthase: A unique glycosyltransferase for biocatalytic glycosylation process development.
Review
New
Nidetzky et al., Graz, Austria. In Biotechnol Adv, Jan 2016
is a glycosyltransferase (GT) long known from plants and more recently discovered in bacteria.
Bacterial glycosyltransferase toxins.
Review
New
Aktories et al., Freiburg, Germany. In Cell Microbiol, Dec 2015
Prototypic for this group of glycosyltransferase toxins are Clostridium difficile toxins A and B, which modify guanine nucleotide-binding proteins of the Rho family.
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis.
New
Mancia et al., New York City, United States. In Nat Commun, Dec 2015
The attachment of a sugar to a hydrophobic polyisoprenyl carrier is the first step for all extracellular glycosylation processes.
Engineered CHO cells for production of diverse, homogeneous glycoproteins.
New
Impact
Clausen et al., Copenhagen, Denmark. In Nat Biotechnol, Aug 2015
We conducted a comprehensive knockout screen of glycosyltransferase genes controlling N-glycosylation in CHO cells and constructed a design matrix that facilitates the generation of desired glycosylation, such as human-like α2,6-linked sialic acid capping.
Synthetic self-adjuvanting glycopeptide cancer vaccines.
Review
Payne et al., Sydney, Australia. In Front Chem, 2014
Due to changes in glycosyltransferase expression during oncogenesis, the glycoproteins of cancer cells often carry highly truncated carbohydrate chains compared to those on healthy cells.
O-GlcNAc and neurodegeneration: biochemical mechanisms and potential roles in Alzheimer's disease and beyond.
Review
Impact
Vocadlo et al., Canada. In Chem Soc Rev, 2014
O-GlcNAc transferase (OGT) is the glycosyltransferase that acts to install O-GlcNAc onto proteins and O-GlcNAcase (OGA) is the glycoside hydrolase that acts to remove O-GlcNAc from proteins.
Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing.
Impact
Eyers et al., Manchester, United Kingdom. In Nat Chem, 2014
Here, we show that biosynthetic enzymes can display unexpected promiscuity, with human glycosyltransferase pp-α-GanT2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgalactosamine, leading to the synthesis of epimeric glycopeptides in vitro.
HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Impact
Walker et al., Boston, United States. In Science, 2014
Host cell factor-1 (HCF-1), a transcriptional co-regulator of human cell-cycle progression, undergoes proteolytic maturation in which any of six repeated sequences is cleaved by the nutrient-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT).
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